PMID- 34875122
OWN - NLM
STAT- MEDLINE
DCOM- 20220328
LR  - 20220401
IS  - 1365-2796 (Electronic)
IS  - 0954-6820 (Linking)
VI  - 291
IP  - 3
DP  - 2022 Mar
TI  - Food allergy and hypersensitivity reactions in children and adults-A review.
PG  - 283-302
LID - 10.1111/joim.13422 [doi]
AB  - Adverse reactions after food intake are commonly reported and a cause of concern 
      and anxiety that can lead to a very strict diet. The severity of the reaction can 
      vary depending on the type of food and mechanism, and it is not always easy to 
      disentangle different hypersensitivity diagnoses, which sometimes can exist 
      simultaneously. After a carefully taken medical history, hypersensitivity to food 
      can often be ruled out or suspected. The most common type of allergic reaction is 
      immunoglobulin E (IgE)-mediated food allergy (prevalence 5-10%). Symptoms vary 
      from mild itching, stomach pain, and rash to severe anaphylaxis. The definition 
      of IgE-mediated food allergy is allergic symptoms combined with specific 
      IgE-antibodies, and therefore only IgE-antibodies to suspected allergens should 
      be analyzed. Nowadays, methods of molecular allergology can help with the 
      diagnostic process. The most common allergens are milk and egg in infants, peanut 
      and tree nuts in children, and fish and shellfish in adults. In young children, 
      milk/egg allergy has a good chance to remit, making it important to follow up and 
      reintroduce the food when possible. Other diseases triggered by food are 
      non-IgE-mediated food allergy, for example, eosinophilic esophagitis, celiac 
      disease, food protein-induced enterocolitis syndrome, and hypersensitivity to 
      milk and biogenic amines. Some of the food hypersensitivities dominate in 
      childhood, others are more common in adults. Interesting studies are ongoing 
      regarding the possibilities of treating food hypersensitivity, such as through 
      oral immunotherapy. The purpose of this review was to provide an overview of the 
      most common types of food hypersensitivity reactions.
CI  - (c) 2021 The Association for the Publication of the Journal of Internal Medicine.
FAU - Tedner, Sandra G
AU  - Tedner SG
AUID- ORCID: 0000-0003-0157-5407
AD  - Department of Women's and Children's Health, Karolinska Institutet, Stockholm, 
      Sweden.
AD  - Pediatric Allergy and Pulmonology Unit at Astrid Lindgren Children's Hospital, 
      Karolinska University Hospital, Stockholm, Sweden.
FAU - Asarnoj, Anna
AU  - Asarnoj A
AD  - Department of Women's and Children's Health, Karolinska Institutet, Stockholm, 
      Sweden.
AD  - Pediatric Allergy and Pulmonology Unit at Astrid Lindgren Children's Hospital, 
      Karolinska University Hospital, Stockholm, Sweden.
FAU - Thulin, Helena
AU  - Thulin H
AD  - Allergy and Lung Department, Sachs' Children and Youth Hospital, Stockholm, 
      Sweden.
AD  - Department of Clinical Science and Education Sodersjukhuset, Karolinska 
      Institutet, Stockholm, Sweden.
FAU - Westman, Marit
AU  - Westman M
AUID- ORCID: 0000-0003-0041-4249
AD  - Division of Immunology and Allergy, Department of Medicine Solna, Karolinska 
      Institutet, Stockholm, Sweden.
AD  - Asthma and Allergy Clinic S:t Goran, Stockholm, Sweden.
FAU - Konradsen, Jon R
AU  - Konradsen JR
AD  - Department of Women's and Children's Health, Karolinska Institutet, Stockholm, 
      Sweden.
AD  - Pediatric Allergy and Pulmonology Unit at Astrid Lindgren Children's Hospital, 
      Karolinska University Hospital, Stockholm, Sweden.
FAU - Nilsson, Caroline
AU  - Nilsson C
AD  - Allergy and Lung Department, Sachs' Children and Youth Hospital, Stockholm, 
      Sweden.
AD  - Department of Clinical Science and Education Sodersjukhuset, Karolinska 
      Institutet, Stockholm, Sweden.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20211222
PL  - England
TA  - J Intern Med
JT  - Journal of internal medicine
JID - 8904841
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Allergens
MH  - Animals
MH  - Child, Preschool
MH  - *Eosinophilic Esophagitis
MH  - Food
MH  - *Food Hypersensitivity/diagnosis
MH  - Humans
MH  - Immunoglobulin E
OTO - NOTNLM
OT  - IgE-mediated food allergy
OT  - biogenic amines
OT  - food hypersensitivity
OT  - immunoglobulin E
OT  - molecular allergology
OT  - non-IgE-mediated food allergy
EDAT- 2021/12/08 06:00
MHDA- 2022/03/29 06:00
CRDT- 2021/12/07 17:31
PHST- 2021/12/08 06:00 [pubmed]
PHST- 2022/03/29 06:00 [medline]
PHST- 2021/12/07 17:31 [entrez]
AID - 10.1111/joim.13422 [doi]
PST - ppublish
SO  - J Intern Med. 2022 Mar;291(3):283-302. doi: 10.1111/joim.13422. Epub 2021 Dec 22.