PMID- 34881105 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220506 IS - 2163-3916 (Print) IS - 2163-3924 (Electronic) IS - 2163-3916 (Linking) VI - 10 IP - 6 DP - 2021 Dec TI - Joint Distraction for Thumb Carpometacarpal Osteoarthritis: 2-Year Follow-up Results of 20 Patients. PG - 502-510 LID - 10.1055/s-0041-1728806 [doi] AB - Background Joint distraction is a fairly new treatment for patients with symptomatic thumb carpometacarpal osteoarthritis (CMC1 OA). A previous pilot study of five patients showed that CMC1 joint distraction is technically feasible. The current study presents the results of CMC1 joint distraction in 20 patients with a 2-year follow-up period. Purposes The primary study aim was to assess if patients with CMC1 OA have better physical function and less pain 2 years after CMC1 joint distraction. Second, we assessed the number of patients who achieved a minimal clinically important difference (MCID) in patient-reported outcome measures at each follow-up time point. Furthermore, this study sought differences on magnetic resonance imaging (MRI) of the CMC1 joint before and after distraction. Adverse events were noted and reported. Methods Twenty patients (median age of 54 years) with symptomatic CMC1 OA and an established indication for a trapeziectomy were enrolled. An external distractor device was placed over the CMC1 joint and left in situ for 8 weeks. Disabilities of the Arm, Shoulder, and Hand (DASH) score, Michigan Hand Outcome Questionnaire (MHQ), visual analogue scale (VAS), and grip strength were recorded preoperatively and at 3, 6, 12, and 24 months postoperatively. Results Two years after joint distraction, physical function and pain scores had improved significantly compared with baseline: DASH from 48 to 17, MHQ from 56 to 83, and VAS for pain from 50 to 18 mm. Fourteen of 19 patients (74%) reached an MCID in DASH and MHQ scores. One patient was not satisfied with treatment outcome and chose to proceed with a trapeziectomy 14 months after initial distraction therapy. Conclusions This study demonstrates that CMC1 joint distraction can postpone more invasive surgical interventions (e.g., trapeziectomy) for at least 2 years. Larger comparative studies are needed to assess the value of CMC1 joint distraction in the treatment of CMC1 OA. Level of Evidence This is a Level IV, prospective case series study. CI - Thieme. All rights reserved. FAU - Ottenhoff, Janna S E AU - Ottenhoff JSE AUID- ORCID: 0000-0002-0359-0654 AD - Department of Plastic, Reconstructive and Hand Surgery, University Medical Center Utrecht, Utrecht, The Netherlands. FAU - Spaans, Anne J AU - Spaans AJ AUID- ORCID: 0000-0002-4959-4562 AD - Department of Orthopedic Surgery, Sint Maartenskliniek, Ubbergen, The Netherlands. FAU - Braakenburg, Assa AU - Braakenburg A AUID- ORCID: 0000-0002-7472-009X AD - Department of Plastic, Reconstructive and Hand Surgery, St. Antonius Hospital, Nieuwegein, The Netherlands. FAU - Teunis, Teun AU - Teunis T AUID- ORCID: 0000-0001-5660-0695 AD - Department of Plastic, Reconstructive and Hand Surgery, University Medical Center Utrecht, Utrecht, The Netherlands. FAU - van Minnen, L Paul AU - van Minnen LP AUID- ORCID: 0000-0001-6421-5631 AD - Department of Plastic Surgery, Royal Adelaide Hospital, Adelaide, Australia. FAU - Mink van der Molen, Aebele B AU - Mink van der Molen AB AUID- ORCID: 0000-0002-9747-4370 AD - Department of Plastic, Reconstructive and Hand Surgery, University Medical Center Utrecht, Utrecht, The Netherlands. AD - Department of Orthopedic Surgery, St. Antonius Hospital, Nieuwegein, The Netherlands. LA - eng PT - Journal Article DEP - 20210504 PL - United States TA - J Wrist Surg JT - Journal of wrist surgery JID - 101603430 PMC - PMC8635830 OTO - NOTNLM OT - carpometacarpal joint OT - external fixator OT - osteoarthritis OT - thumb OT - treatment COIS- Conflict of Interest T.T. has or may have receive payment or benefits from AO Trauma, DePuy Synthes, and PATIENT + , outside the submitted work. J.S.E.O., A.J.S., A.B., L.P.v.M., and A.B.M.v.d.M. certify that they have no commercial associations (e.g., consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article. EDAT- 2021/12/10 06:00 MHDA- 2021/12/10 06:01 PMCR- 2022/05/04 CRDT- 2021/12/09 07:03 PHST- 2020/10/30 00:00 [received] PHST- 2021/03/10 00:00 [accepted] PHST- 2021/12/09 07:03 [entrez] PHST- 2021/12/10 06:00 [pubmed] PHST- 2021/12/10 06:01 [medline] PHST- 2022/05/04 00:00 [pmc-release] AID - 2000152cra [pii] AID - 10.1055/s-0041-1728806 [doi] PST - epublish SO - J Wrist Surg. 2021 May 4;10(6):502-510. doi: 10.1055/s-0041-1728806. eCollection 2021 Dec.