PMID- 34881131
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211211
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 13
IP  - 12
DP  - 2021 Dec
TI  - Role of Acute Physiology, Age, and Chronic Health Evaluation (APACHE) II Score in 
      Predicting Outcomes of Peritonitis Due to Hollow Viscous Perforation: A 
      Prospective Observational Study.
PG  - e20155
LID - 10.7759/cureus.20155 [doi]
LID - e20155
AB  - Background The Acute Physiology and Chronic Health Evaluation II (APACHE II) is 
      the most commonly used severity-of-disease scoring system in ICUs worldwide. 
      There is a paucity of data describing the role of APACHE II score in predicting 
      outcomes of peritonitis due to hollow viscous perforation. This study aims at 
      identifying the importance of the APACHE II score in predicting outcomes of 
      patients with peritonitis secondary to hollow viscus perforation. Methods The 
      study is a prospective, observational study that included all the patients 
      diagnosed with perforation peritonitis who underwent emergency laparotomy and 
      were admitted to the Department of Surgery from May 2017 to May 2018. APACHE II 
      scores were assigned to all patients in order to calculate their individual risk 
      of mortality before undergoing emergency surgery. The accuracy in outcome 
      prediction of the APACHE II system was assessed by means of receiver operating 
      characteristic (ROC) curve and Pearson correlation coefficient and its 
      significance test. Result A total of 50 patients with perforation peritonitis 
      were included in this study. Peptic ulcer disease was the major etiology leading 
      to perforation in 54% of patients, followed by gangrenous bowel. The mean APACHE 
      II score was 9.54. Out of the 50 patients, seven patients succumbed to the 
      illness. All the seven patients whose APACHE II score > 16 developed systemic 
      complications, and three of them developed a local complication. Conclusion 
      APACHE II score correlated well with the outcome in the current study, and APACHE 
      II score also correlated well with the hospital and ICU stay.
CI  - Copyright (c) 2021, Bylapudi et al.
FAU - Bylapudi, Seshu Kumar
AU  - Bylapudi SK
AD  - General Surgery, Pilgrim Hospital, Boston, GBR.
FAU - Nanjan, Sugunesh
AU  - Nanjan S
AD  - Surgery, Royal Gwent Hospital, Newport, GBR.
FAU - Ramasamy, Sadhasivam
AU  - Ramasamy S
AD  - General Surgery, Milton Keynes University Hospital, Milton Keynes, GBR.
FAU - Kannan, Amudhan
AU  - Kannan A
AD  - Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, 
      Puducherry, IND.
FAU - Kantamaneni, Ketan
AU  - Kantamaneni K
AD  - Surgery, Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research 
      Foundation, Gannavaram, IND.
FAU - Nangireddi, Shalini
AU  - Nangireddi S
AD  - Obstetrics and Gynaecology, Lourde Hospital, Kannur, IND.
FAU - Atluri, Lakshmi Malvika
AU  - Atluri LM
AD  - Surgery, Dr. Pinnamaneni Siddhartha Institute of Medical Science, Gannavaram, 
      IND.
FAU - Kondi, Suresh
AU  - Kondi S
AD  - Surgery, Citi Neuro Centre, Hyderabad, IND.
FAU - Rajkumar, K S
AU  - Rajkumar KS
AD  - General Surgery, Kovai Medical Center, Coimbatore, IND.
LA  - eng
PT  - Journal Article
DEP - 20211204
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC8643078
OTO - NOTNLM
OT  - apache
OT  - morbidity
OT  - mortality
OT  - outcome
OT  - peptic ulcer disease
OT  - perforation
OT  - peritonitis
OT  - prognosis
OT  - score
OT  - surgery
COIS- The authors have declared that no competing interests exist.
EDAT- 2021/12/10 06:00
MHDA- 2021/12/10 06:01
PMCR- 2021/12/04
CRDT- 2021/12/09 07:03
PHST- 2021/12/04 00:00 [accepted]
PHST- 2021/12/09 07:03 [entrez]
PHST- 2021/12/10 06:00 [pubmed]
PHST- 2021/12/10 06:01 [medline]
PHST- 2021/12/04 00:00 [pmc-release]
AID - 10.7759/cureus.20155 [doi]
PST - epublish
SO  - Cureus. 2021 Dec 4;13(12):e20155. doi: 10.7759/cureus.20155. eCollection 2021 
      Dec.