PMID- 34881704 OWN - NLM STAT- MEDLINE DCOM- 20220117 LR - 20220117 IS - 1308-4488 (Electronic) IS - 1016-5169 (Linking) VI - 49 IP - 8 DP - 2021 Dec TI - Revascularization strategies in patients with infective endocarditis-related ST-elevation myocardial infarction: The STEMI-ENDO Registry. PG - 654-665 LID - 10.5543/tkda.2021.21173 [doi] AB - OBJECTIVE: Infective endocarditis (IE)-related ST elevation myocardial infarction (STEMI) is extremely rare. A clear clinical consensus is lacking regarding the management of this emergency. In this study, we aimed to describe the clinical outcomes of treatment strategies in this patient population. METHODS: The study population comprised 19 retrospectively evaluated patients (nine women; mean age 52+/-11.8 years) with a diagnosis of IE-related STEMI. Transesophageal echocardiography detected vegetation in all the patients. The study population was divided into two groups on the basis of in-hospital mortality. RESULTS: Major clinical manifestations included dyspnea (89.5%), fever (78.9%), and chest pain (63.2%). Catheter-based coronary angiography was performed in all the patients. The causative agent was isolated in all the cases, and Staphylococcus aureus was identified in seven (36.8%). The most common infarction was in the left anterior descending artery (n=12 [63.2%]). The treatment strategy consisted of mechanical thrombectomy (n=1), valve replacement following stent implantation (n=5), direct balloon angioplasty (n=4), valve replacement along with coronary artery bypass grafting (CABG; n=6), and medical follow-up (n=3). Moreover, thrombolysis in myocardial infarction III flow was significantly higher in the survival group (100% vs. 0%, p<0.001). All these patients preferred CABG or stent implantation for revascularization. CONCLUSION: The current data suggest that a revascularization strategy with stent implantation or revascularization with CABG has a lower mortality rate in patients with IE-related STEMI. FAU - Guner, Ahmet AU - Guner A AD - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Uygun Kizmaz, Yesim AU - Uygun Kizmaz Y AD - Department of Infectious Diseases and Clinical Microbiology, Kosuyolu Kartal Heart Training and Research Hospital, Istanbul, Turkey. FAU - Gunduz, Sabahattin AU - Gunduz S AD - Department of Cardiology, Bahcesehir University School of Medicine, Istanbul, Turkey. FAU - Arslan, Cagdas AU - Arslan C AD - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Ozkan Ozturk, Serpil AU - Ozkan Ozturk S AD - Department of Infectious Diseases and Clinical Microbiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Alizade, Elnur AU - Alizade E AD - Department of Cardiology, Kosuyolu Kartal Heart Training and Research Hospital, Istanbul, Turkey. FAU - Kalcik, Macit AU - Kalcik M AD - Department of Cardiology, Hitit University School of Medicine, Corum, Turkey. FAU - Kahraman, Serkan AU - Kahraman S AD - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Akman, Cemalettin AU - Akman C AD - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Kalkan, Ali Kemal AU - Kalkan AK AD - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Ozkan, Mehmet AU - Ozkan M AD - Department of Cardiology, Kosuyolu Kartal Heart Training and Research Hospital, Istanbul, Turkey. LA - eng PT - Journal Article PL - Turkey TA - Turk Kardiyol Dern Ars JT - Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir JID - 9426239 SB - IM MH - Angioplasty, Balloon/statistics & numerical data MH - Chest Pain/etiology MH - Coronary Angiography MH - Dyspnea/etiology MH - Echocardiography, Transesophageal MH - Endocarditis/*complications/diagnostic imaging/microbiology MH - Female MH - Fever/etiology MH - Heart Valve Prosthesis Implantation/statistics & numerical data MH - Hospital Mortality MH - Humans MH - Male MH - Mechanical Thrombolysis/statistics & numerical data MH - Middle Aged MH - Myocardial Revascularization/*methods/mortality MH - Registries MH - Retrospective Studies MH - ST Elevation Myocardial Infarction/etiology/mortality/*surgery MH - Stents EDAT- 2021/12/10 06:00 MHDA- 2022/01/18 06:00 CRDT- 2021/12/09 08:38 PHST- 2021/12/09 08:38 [entrez] PHST- 2021/12/10 06:00 [pubmed] PHST- 2022/01/18 06:00 [medline] AID - 10.5543/tkda.2021.21173 [doi] PST - ppublish SO - Turk Kardiyol Dern Ars. 2021 Dec;49(8):654-665. doi: 10.5543/tkda.2021.21173.