PMID- 34889226
OWN - NLM
STAT- MEDLINE
DCOM- 20220207
LR  - 20231108
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 100
IP  - 49
DP  - 2021 Dec 10
TI  - Effect of electroacupuncture on glucose and lipid metabolism in type 2 diabetes: 
      A protocol for systematic review and meta-analysis.
PG  - e27762
LID - 10.1097/MD.0000000000027762 [doi]
LID - e27762
AB  - BACKGROUND: Type 2 diabetes mellitus (T2DM) is a global pandemic with a 
      significant negative impact on health-related quality of life. Worldwide, the 
      prevalence of T2DM has almost doubled since 1980. Although multiple systematic 
      reviews and clinical trials have suggested that electroacupuncture could be 
      effective for T2DM treatment, whether it can improve glucose and lipid metabolism 
      has not been systematically reviewed. METHODS: We searched PubMed, Medline, 
      Embase, Web of Science, Cochrane Central Register of Controlled Trials, China 
      National Knowledge Infrastructure, Chinese Biomedical Literature Database, 
      Chinese Scientific Journal Database, and Wan-Fang Database from the date of 
      creation to December 2022. Language is limited to both Chinese and English 
      languages. Clinical randomized controlled trials related to acupuncture for T2DM 
      were included in this study. Fasting plasma glucose, fasting insulin, lipid 
      profile, and glycated hemoglobin levels were the primary outcomes. In addition, 
      we manually retrieved other resources, including reference lists of identified 
      publications, conference articles, and gray literature. Research selection, data 
      extraction, and research quality assessments were independently completed by 2 
      researchers. RESULTS: This study provides more options for clinicians and 
      patients to treat obese patients with type 2 diabetes. CONCLUSION: In this study, 
      we aimed to summarize and assess the effectiveness and safety of EA as a 
      supplemental method to treat T2DM patients from clinical trials and provide more 
      options for clinicians and patients to treat T2DM. TRIAL REGISTRATION: This study 
      was registered at INPLASY with registration number INPLASY202180008 
      (https://inplasy.com/inplasy-2021-8-0008/). SYSTEMATIC REVIEW REGISTRATION: 
      INPLASY202180008.
CI  - Copyright (c) 2021 the Author(s). Published by Wolters Kluwer Health, Inc.
FAU - Han, Yiran
AU  - Han Y
AD  - Department of Acupuncture and Tuina, Changchun University of Chinese Medicine, 
      Changchun, China.
FAU - Lu, Zeyuan
AU  - Lu Z
AD  - Department of Pharmacy, The Second Hospital of Jilin University, Jilin, China.
FAU - Chen, Shaotao
AU  - Chen S
AD  - Department of Acupuncture and Tuina, Changchun University of Chinese Medicine, 
      Changchun, China.
AD  - Acupuncture and Massage Center of the Third Affiliated Clinical Hospital of 
      Changchun University of Chinese Medicine, Changchun, China.
FAU - Gao, Tianjiao
AU  - Gao T
AD  - Department of Acupuncture and Tuina, Changchun University of Chinese Medicine, 
      Changchun, China.
FAU - Gang, Xiaochao
AU  - Gang X
AD  - Department of Acupuncture and Tuina, Changchun University of Chinese Medicine, 
      Changchun, China.
FAU - Pan, Ting
AU  - Pan T
AD  - Department of Acupuncture and Tuina, Changchun University of Chinese Medicine, 
      Changchun, China.
FAU - Meng, Meng
AU  - Meng M
AD  - Department of Acupuncture and Tuina, Changchun University of Chinese Medicine, 
      Changchun, China.
FAU - Liu, Mingjun
AU  - Liu M
AUID- ORCID: 0000-0003-0077-800
AD  - Department of Acupuncture and Tuina, Changchun University of Chinese Medicine, 
      Changchun, China.
AD  - Acupuncture and Massage Center of the Third Affiliated Clinical Hospital of 
      Changchun University of Chinese Medicine, Changchun, China.
LA  - eng
GR  - 82174525/National Natural Science Foundation of China/
PT  - Clinical Trial Protocol
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - *Acupuncture Therapy
MH  - Diabetes Mellitus, Type 2/*therapy
MH  - *Electroacupuncture
MH  - Glucose
MH  - Humans
MH  - Lipid Metabolism
MH  - Meta-Analysis as Topic
MH  - Quality of Life
MH  - Randomized Controlled Trials as Topic
MH  - Research Design
MH  - Systematic Reviews as Topic
PMC - PMC8663878
COIS- The authors have no conflicts of interest to disclose.
EDAT- 2021/12/11 06:00
MHDA- 2022/02/08 06:00
PMCR- 2021/12/10
CRDT- 2021/12/10 08:43
PHST- 2021/10/27 00:00 [received]
PHST- 2021/10/28 00:00 [accepted]
PHST- 2021/12/10 08:43 [entrez]
PHST- 2021/12/11 06:00 [pubmed]
PHST- 2022/02/08 06:00 [medline]
PHST- 2021/12/10 00:00 [pmc-release]
AID - 00005792-202112100-00007 [pii]
AID - MD-D-21-07222 [pii]
AID - 10.1097/MD.0000000000027762 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2021 Dec 10;100(49):e27762. doi: 
      10.1097/MD.0000000000027762.