PMID- 34890695
OWN - NLM
STAT- MEDLINE
DCOM- 20220523
LR  - 20230119
IS  - 1097-6779 (Electronic)
IS  - 0016-5107 (Linking)
VI  - 95
IP  - 6
DP  - 2022 Jun
TI  - Novel classification for adverse events in GI endoscopy: the AGREE 
      classification.
PG  - 1078-1085.e8
LID - S0016-5107(21)01867-8 [pii]
LID - 10.1016/j.gie.2021.11.038 [doi]
AB  - BACKGROUND AND AIMS: Standardized registration and evaluation of adverse events 
      (AEs) are essential to assess the safety of endoscopic procedures. We propose a 
      novel classification system, named adverse events in GI endoscopy (AGREE), 
      adapted from a widely accepted surgical tool. METHODS: The Clavien-Dindo 
      classification for surgical AEs was adapted for endoscopy. To validate the novel 
      classification, we assessed if the severity of AEs, as perceived by 10 
      endoscopists, 10 endoscopy nurses, and 10 patients, corresponded with the 
      severity grading used in the AGREE classification in 10 pairwise comparisons. We 
      additionally assessed the correlation between the AGREE classification and the 
      American Society for Gastrointestinal Endoscopy (ASGE) classification. The 
      acceptability of the AGREE classification was evaluated through an international 
      questionnaire. RESULTS: The perception of endoscopists, endoscopy nurses, and 
      patients corresponded with the severity grading of the AGREE classification in 
      80% of cases (238/299). The AGREE classification significantly correlated with 
      the ASGE classification (rho = .760). Fifty-seven of 84 experts (68%) completed a 
      questionnaire regarding the acceptability of the AGREE classification. The 
      experts consulted considered the AGREE classification as simple (86%), 
      reproducible (98%), logical (98%), and useful (96%). Most case presentations 
      (84%) were correctly graded according to the AGREE classification. CONCLUSIONS: 
      The AGREE classification provides a standardized and reproducible approach to the 
      assessment of AEs in diagnostic and therapeutic GI endoscopy. Broad 
      implementation of the AGREE classification may facilitate the evaluation of AEs 
      across different endoscopists, disciplines, endoscopy services, and regions. This 
      standardization of AE reporting will support improved quality assurance in GI 
      endoscopy.
CI  - Copyright (c) 2021 American Society for Gastrointestinal Endoscopy. Published by 
      Elsevier Inc. All rights reserved.
FAU - Nass, Karlijn J
AU  - Nass KJ
AD  - Department of Gastroenterology and Hepatology, Research Institute Amsterdam 
      Gastroenterology & Metabolism, Amsterdam University Medical Center, Amsterdam, 
      the Netherlands.
FAU - Zwager, Liselotte W
AU  - Zwager LW
AD  - Department of Gastroenterology and Hepatology, Research Institute Amsterdam 
      Gastroenterology & Metabolism, Amsterdam University Medical Center, Amsterdam, 
      the Netherlands.
FAU - van der Vlugt, Manon
AU  - van der Vlugt M
AD  - Department of Gastroenterology and Hepatology, Research Institute Amsterdam 
      Gastroenterology & Metabolism, Amsterdam University Medical Center, Amsterdam, 
      the Netherlands.
FAU - Dekker, Evelien
AU  - Dekker E
AD  - Department of Gastroenterology and Hepatology, Research Institute Amsterdam 
      Gastroenterology & Metabolism, Amsterdam University Medical Center, Amsterdam, 
      the Netherlands.
FAU - Bossuyt, Patrick M M
AU  - Bossuyt PMM
AD  - Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam 
      University Medical Center, Amsterdam, the Netherlands.
FAU - Ravindran, Srivathsan
AU  - Ravindran S
AD  - Wolfson Unit for Endoscopy, St Mark's Hospital, London, UK; Department of Surgery 
      and Cancer, Imperial College London, London, UK.
FAU - Thomas-Gibson, Siwan
AU  - Thomas-Gibson S
AD  - Wolfson Unit for Endoscopy, St Mark's Hospital, London, UK; Department of 
      Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
FAU - Fockens, Paul
AU  - Fockens P
AD  - Department of Gastroenterology and Hepatology, Research Institute Amsterdam 
      Gastroenterology & Metabolism, Amsterdam University Medical Center, Amsterdam, 
      the Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20211208
PL  - United States
TA  - Gastrointest Endosc
JT  - Gastrointestinal endoscopy
JID - 0010505
SB  - IM
CIN - Gastrointest Endosc. 2022 Jun;95(6):1086-1087. PMID: 35461684
CIN - Gastrointest Endosc. 2022 Jun;95(6):1280. PMID: 35589207
MH  - Endoscopy
MH  - *Endoscopy, Gastrointestinal/adverse effects
MH  - *Gastroenterology
MH  - Humans
MH  - Surveys and Questionnaires
EDAT- 2021/12/11 06:00
MHDA- 2022/05/24 06:00
CRDT- 2021/12/10 20:14
PHST- 2021/09/07 00:00 [received]
PHST- 2021/11/12 00:00 [accepted]
PHST- 2021/12/11 06:00 [pubmed]
PHST- 2022/05/24 06:00 [medline]
PHST- 2021/12/10 20:14 [entrez]
AID - S0016-5107(21)01867-8 [pii]
AID - 10.1016/j.gie.2021.11.038 [doi]
PST - ppublish
SO  - Gastrointest Endosc. 2022 Jun;95(6):1078-1085.e8. doi: 10.1016/j.gie.2021.11.038. 
      Epub 2021 Dec 8.