PMID- 34891023
OWN - NLM
STAT- MEDLINE
DCOM- 20220328
LR  - 20220401
IS  - 1872-7506 (Electronic)
IS  - 0925-4927 (Linking)
VI  - 319
DP  - 2022 Jan
TI  - Appetitive aggression is associated with lateralized activation in nucleus 
      accumbens.
PG  - 111425
LID - S0925-4927(21)00177-3 [pii]
LID - 10.1016/j.pscychresns.2021.111425 [doi]
AB  - Aggression can have a hedonistic aspect in predisposed individuals labeled as 
      appetitive aggression. The present study investigates the neurobiological 
      correlates of this appetitive type of aggression in non-clinical samples from 
      community. Applying functional magnet resonance imaging (fMRI), we tested whether 
      20 martial artists compared to 26 controls had a higher activation in the nucleus 
      accumbens (NAcc), a central part of the dopaminergic, mesolimbic reward system. 
      Subjects had to watch violent vs. neutral pictures representing appetitive 
      aggression. The affinity towards hedonistic violence was assessed by the 
      Appetitive and Facilitative Aggression Scale (AFAS). Furthermore, the subjects 
      rated all the pictures with regard to how pleasant and violent they were. The 
      martial artists reported a higher AFAS-score and a more positive perception of 
      violent pictures. On the neural level, across all subjects, there was a 
      significant positive correlation between the AFAS-score and the activation in the 
      left NAcc and an inverse association with the activation of the right NAcc when 
      watching violent compared to neutral pictures. This lateralization effect 
      indicates a different processing of hedonistic aspects of aggression in the two 
      hemispheres.
CI  - Copyright (c) 2021 Elsevier B.V. All rights reserved.
FAU - Schone, Maria
AU  - Schone M
AD  - Department of Psychiatry and Psychotherapy, Otto-von-Guericke University, 
      Magdeburg, Germany; Salus Institute, Salus gGmbH, Magdeburg, Germany. Electronic 
      address: mariaschoene@t-online.de.
FAU - Seidenbecher, Stephanie
AU  - Seidenbecher S
AD  - Department of Psychiatry and Psychotherapy, Otto-von-Guericke University, 
      Magdeburg, Germany; Salus Institute, Salus gGmbH, Magdeburg, Germany.
FAU - Kaufmann, Jorn
AU  - Kaufmann J
AD  - Department of Neurology, Otto-von-Guericke University, Magdeburg, Germany.
FAU - Antonucci, Linda Antonella
AU  - Antonucci LA
AD  - Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, 
      Munich, Germany; Department of Education, Psychology, Communication, University 
      of Bari Aldo Moro, Bari, Italy.
FAU - Frodl, Thomas
AU  - Frodl T
AD  - Department of Psychiatry and Psychotherapy, Otto-von-Guericke University, 
      Magdeburg, Germany; Department of Psychiatry and Institute of Neuroscience, 
      Dublin, Ireland; Center for Behavioral Brain Sciences, Otto-von-Guericke 
      University, Magdeburg, Germany; German Center for Neurodegenerative Diseases, 
      Otto-von-Guericke University, Magdeburg, Germany; Department of Psychiatry, 
      Psychotherapy, and Psychosomatic, RWTH-University, Aachen, Germany.
FAU - Koutsouleris, Nikolaos
AU  - Koutsouleris N
AD  - Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, 
      Munich, Germany.
FAU - Schiltz, Kolja
AU  - Schiltz K
AD  - Department of Psychiatry and Psychotherapy, Otto-von-Guericke University, 
      Magdeburg, Germany; Department of Forensic Psychiatry, Mental Hospital of the 
      Ludwig-Maximilians-University, Munich, Germany.
FAU - Bogerts, Bernhard
AU  - Bogerts B
AD  - Department of Psychiatry and Psychotherapy, Otto-von-Guericke University, 
      Magdeburg, Germany; Salus Institute, Salus gGmbH, Magdeburg, Germany.
LA  - eng
PT  - Journal Article
DEP - 20211204
PL  - Netherlands
TA  - Psychiatry Res Neuroimaging
JT  - Psychiatry research. Neuroimaging
JID - 101723001
SB  - IM
MH  - *Aggression/physiology
MH  - Humans
MH  - Magnetic Resonance Imaging/methods
MH  - *Nucleus Accumbens/diagnostic imaging/physiology
MH  - Reward
MH  - Violence
OTO - NOTNLM
OT  - FMRI
OT  - Hedonistic violence
OT  - Martial arts
EDAT- 2021/12/11 06:00
MHDA- 2022/03/29 06:00
CRDT- 2021/12/10 20:25
PHST- 2021/07/27 00:00 [received]
PHST- 2021/11/14 00:00 [revised]
PHST- 2021/12/02 00:00 [accepted]
PHST- 2021/12/11 06:00 [pubmed]
PHST- 2022/03/29 06:00 [medline]
PHST- 2021/12/10 20:25 [entrez]
AID - S0925-4927(21)00177-3 [pii]
AID - 10.1016/j.pscychresns.2021.111425 [doi]
PST - ppublish
SO  - Psychiatry Res Neuroimaging. 2022 Jan;319:111425. doi: 
      10.1016/j.pscychresns.2021.111425. Epub 2021 Dec 4.