PMID- 34894816
OWN - NLM
STAT- MEDLINE
DCOM- 20220517
LR  - 20220517
IS  - 1940-2465 (Electronic)
IS  - 1066-8969 (Linking)
VI  - 30
IP  - 4
DP  - 2022 Jun
TI  - Primary Sclerosing Epithelioid Fibrosarcoma of the Kidney: A Case Report and 
      Review of the Literature.
PG  - 437-442
LID - 10.1177/10668969211065107 [doi]
AB  - Sclerosing epithelioid fibrosarcoma (SEF) is a rare variant of fibrosarcoma. We 
      report one case of primary kidney SEF occurring in a 38-year-old man. 
      Microscopically, epithelioid neoplastic cells are mainly arranged in cords and 
      nests embedded in the dense sclerosing stroma. Diffuse immunohistochemical 
      staining for MUC4 in neoplastic cells and the presence of the EWSR1 gene split by 
      fluorescence in situ hybridization (FISH) analysis confirmed the histological 
      diagnosis. Primary kidney SEF is extremely rare, the differential diagnosis 
      strategy broadly includes a series of tumors with epithelioid morphology and 
      sclerosing matrix, mainly including sclerosing variants of clear cell sarcoma of 
      the kidney (CCSK), renal synovial sarcoma (SS), renal solitary fibrous tumor 
      (SFT), metanephric stromal tumor (MST), sclerosing perivascular epithelioid cell 
      tumor (PEComa), and carcinomas, and immunohistochemical expression of MUC4 and 
      evidence of the EWSR1 gene split are helpful in making a definite diagnosis.
FAU - Peng, Yan
AU  - Peng Y
AUID- ORCID: 0000-0001-9972-9640
AD  - 117850The Third Affiliated Hospital of Soochow University, Changzhou First 
      People's Hospital, Changzhou City, Jiangsu Province, China.
FAU - Chen, Tongbing
AU  - Chen T
AD  - 117850The Third Affiliated Hospital of Soochow University, Changzhou First 
      People's Hospital, Changzhou City, Jiangsu Province, China.
FAU - Zhang, Dachuan
AU  - Zhang D
AUID- ORCID: 0000-0002-9778-3456
AD  - 117850The Third Affiliated Hospital of Soochow University, Changzhou First 
      People's Hospital, Changzhou City, Jiangsu Province, China.
FAU - Wu, Chao
AU  - Wu C
AD  - 117850The Third Affiliated Hospital of Soochow University, Changzhou First 
      People's Hospital, Changzhou City, Jiangsu Province, China.
FAU - Lei, Ting
AU  - Lei T
AD  - 117850The Third Affiliated Hospital of Soochow University, Changzhou First 
      People's Hospital, Changzhou City, Jiangsu Province, China.
FAU - Shi, Yongqiang
AU  - Shi Y
AD  - 117850The Third Affiliated Hospital of Soochow University, Changzhou First 
      People's Hospital, Changzhou City, Jiangsu Province, China.
FAU - Xia, Cunyan
AU  - Xia C
AD  - 117850The Third Affiliated Hospital of Soochow University, Changzhou First 
      People's Hospital, Changzhou City, Jiangsu Province, China.
FAU - Li, Qing
AU  - Li Q
AD  - 117850The Third Affiliated Hospital of Soochow University, Changzhou First 
      People's Hospital, Changzhou City, Jiangsu Province, China.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
DEP - 20211213
PL  - United States
TA  - Int J Surg Pathol
JT  - International journal of surgical pathology
JID - 9314927
RN  - 0 (Biomarkers, Tumor)
SB  - IM
MH  - Biomarkers, Tumor/genetics/metabolism
MH  - Epithelioid Cells/pathology
MH  - Female
MH  - *Fibrosarcoma/diagnosis/genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Kidney/pathology
MH  - *Kidney Neoplasms/diagnosis/genetics
MH  - Male
OTO - NOTNLM
OT  - EWSR1
OT  - clinicopathologic features
OT  - immunophenotype
OT  - kidney
OT  - sclerosing epithelioid fibrosarcoma
EDAT- 2021/12/14 06:00
MHDA- 2022/05/18 06:00
CRDT- 2021/12/13 11:19
PHST- 2021/12/14 06:00 [pubmed]
PHST- 2022/05/18 06:00 [medline]
PHST- 2021/12/13 11:19 [entrez]
AID - 10.1177/10668969211065107 [doi]
PST - ppublish
SO  - Int J Surg Pathol. 2022 Jun;30(4):437-442. doi: 10.1177/10668969211065107. Epub 
      2021 Dec 13.