PMID- 34902719
OWN - NLM
STAT- MEDLINE
DCOM- 20220111
LR  - 20220111
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1662
DP  - 2022 Jan 11
TI  - New low viscous hydrophobic deep eutectic solvents for the ultrasound-assisted 
      dispersive liquid-liquid microextraction of endocrine-disrupting phenols in 
      water, milk and beverage.
PG  - 462728
LID - S0021-9673(21)00850-5 [pii]
LID - 10.1016/j.chroma.2021.462728 [doi]
AB  - In the present work, several new hydrophobic deep eutectic solvents (HDESs) were 
      prepared with quaternary ammonium salts as hydrogen bond acceptors (HBAs) and 
      salicylate esters as hydrogen bond donors (HBDs). Then, the obtained HDESs were 
      used as extraction solvents to establish an ultrasound-assisted dispersive 
      liquid-liquid microextraction method combined with high-performance liquid 
      chromatography-ultraviolet detection technique for the determination of four 
      endocrine-disrupting phenols (EDPs) compounds. One of the obtained HDESs composed 
      of tetrabutylammonium chloride (N(4444)Cl) and methyl salicylate possessed a 
      viscosity of 89.28 mPa*s lower than most reported ionic HDESs (>200 mPa*s), and 
      the low viscous HDES was selected as the optimal extraction solvent. Several key 
      parameters affecting the extraction efficiency were investigated, including the 
      type and volume of HDES, ultrasound time, sample solution pH and salt addition. 
      Under the optimized experimental conditions, the proposed method had good 
      coefficients of determination (R(2) > 0.9976) in the linear range of 0.5-400 
      microg*L(-1), the limits of quantification and limits of detection respectively were 
      0.5-2.5 microg*L(-1) and 0.25-1 microg*L(-1), and the recoveries were in the range of 
      81.79-109.82%. Finally, the method was used for the preconcentration and 
      determination of EDPs in different samples, including bottled water, tea beverage 
      and milk.
CI  - Copyright (c) 2021 Elsevier B.V. All rights reserved.
FAU - Qiao, Lizhen
AU  - Qiao L
AD  - State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 
      116023, China; School of Chemical Engineering, Dalian University of Technology, 
      Panjin 124221, China. Electronic address: qiaolz@dlut.edu.cn.
FAU - Sun, Ruiting
AU  - Sun R
AD  - State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 
      116023, China; School of Chemical Engineering, Dalian University of Technology, 
      Panjin 124221, China.
FAU - Tao, Yuan
AU  - Tao Y
AD  - State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 
      116023, China; School of Chemical Engineering, Dalian University of Technology, 
      Panjin 124221, China.
FAU - Yan, Yang
AU  - Yan Y
AD  - State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 
      116023, China; School of Chemical Engineering, Dalian University of Technology, 
      Panjin 124221, China.
LA  - eng
PT  - Journal Article
DEP - 20211203
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Deep Eutectic Solvents)
RN  - 0 (Phenols)
RN  - 0 (Solvents)
RN  - 0 (Water Pollutants, Chemical)
RN  - 059QF0KO0R (Water)
SB  - IM
MH  - Animals
MH  - Beverages
MH  - Deep Eutectic Solvents
MH  - Limit of Detection
MH  - *Liquid Phase Microextraction
MH  - Milk/chemistry
MH  - Phenols
MH  - Solvents
MH  - Viscosity
MH  - Water
MH  - *Water Pollutants, Chemical/analysis
OTO - NOTNLM
OT  - Dispersive liquid-liquid microextraction
OT  - Endocrine-disrupting phenols
OT  - Low viscous hydrophobic deep eutectic solvent
COIS- Declaration of Competing Interest There was no conflict of interest to declare.
EDAT- 2021/12/14 06:00
MHDA- 2022/01/12 06:00
CRDT- 2021/12/13 20:23
PHST- 2021/09/23 00:00 [received]
PHST- 2021/11/17 00:00 [revised]
PHST- 2021/11/18 00:00 [accepted]
PHST- 2021/12/14 06:00 [pubmed]
PHST- 2022/01/12 06:00 [medline]
PHST- 2021/12/13 20:23 [entrez]
AID - S0021-9673(21)00850-5 [pii]
AID - 10.1016/j.chroma.2021.462728 [doi]
PST - ppublish
SO  - J Chromatogr A. 2022 Jan 11;1662:462728. doi: 10.1016/j.chroma.2021.462728. Epub 
      2021 Dec 3.