PMID- 34905796 OWN - NLM STAT- MEDLINE DCOM- 20220630 LR - 20220823 IS - 1438-8812 (Electronic) IS - 0013-726X (Linking) VI - 54 IP - 7 DP - 2022 Jul TI - Novel 15-mm-long lumen-apposing metal stent for endoscopic ultrasound-guided drainage of pancreatic fluid collections located >/=10 mm from the luminal wall. PG - 706-711 LID - 10.1055/a-1682-7095 [doi] AB - BACKGROUND: Endoscopic ultrasound (EUS)-guided drainage of pancreatic fluid collections (PFCs) by cautery-enhanced lumen-apposing metal stents (LAMS) has largely been limited to collections located < 10 mm from the luminal wall. We present outcomes of the use of a novel 15-mm-long cautery-enhanced LAMS for drainage of PFCs located >/= 10 mm away. METHODS: This international, multicenter study analyzed all adults with PFCs located >/= 10 mm from the luminal wall who were treated by EUS-guided drainage using the 15-mm-long cautery-enhanced LAMS. The primary outcome was technical success. Secondary outcomes included clinical success (decrease in PFC size by >/= 50 % at 30 days and resolution of clinical symptoms without surgical intervention), complications, and recurrence. RESULTS: 35 patients (median age 57 years; interquartile range [IQR] 47-64 years; 49 % male) underwent novel LAMS placement for drainage of PFCs (26 walled-off necrosis, 9 pseudocysts), measuring 85 mm (IQR 64-117) maximal diameter and located 11.8 mm (IQR 10-12.3; range 10-14) from the gastric/duodenal wall. Technical and clinical success were high (both 97 %), with recurrence in one patient (3 %) at a median follow-up of 123 days (58-236). Three complications occurred (9 %; one mild, two moderate). CONCLUSIONS: The 15-mm-long cautery-enhanced LAMS was feasible and safe for drainage of PFCs located 10-14 mm from the luminal wall. CI - Thieme. All rights reserved. FAU - Zhang, Linda Y AU - Zhang LY AD - Department of Gastroenterology and Hepatology, Johns Hopkins Medicine, Baltimore, Maryland, United States. FAU - Kunda, Rastislav AU - Kunda R AUID- ORCID: 0000-0001-5632-2402 AD - Department of Surgery, Department of Gastroenterology-Hepatology, Department of Advanced Interventional Endoscopy, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium. FAU - Aerts, Maridi AU - Aerts M AD - Department of Gastroenterology and Hepatology, Universitair Ziekenhuis Brussel (UZB)/Vrije Universiteit Brussel (VUB), Brussels, Belgium. FAU - Messaoudi, Nouredin AU - Messaoudi N AD - Department of Surgery, Universitair Ziekenhuis Brussel (UZB)/Vrije Universiteit Brussel (VUB), Brussels, Belgium. FAU - Pawa, Rishi AU - Pawa R AD - Department of Gastroenterology, Wake Forest Baptist Medical Center, Winston Salem, North Carolina, United States. FAU - Pawa, Swati AU - Pawa S AD - Department of Gastroenterology, Wake Forest Baptist Medical Center, Winston Salem, North Carolina, United States. FAU - Robles-Medranda, Carlos AU - Robles-Medranda C AUID- ORCID: 0000-0003-2434-3369 AD - Endoscopy Division, Instituto Ecuatoriano de Enfermedades Digestivas, Guayaquil, Ecuador. FAU - Oleas, Roberto AU - Oleas R AD - Endoscopy Division, Instituto Ecuatoriano de Enfermedades Digestivas, Guayaquil, Ecuador. FAU - Al-Haddad, Mohammad A AU - Al-Haddad MA AUID- ORCID: 0000-0003-1641-9976 AD - Department of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, United States. FAU - Obaitan, Itegbemie AU - Obaitan I AUID- ORCID: 0000-0001-5002-6821 AD - Department of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, United States. FAU - Muniraj, Thiruvengadam AU - Muniraj T AD - Department of Gastroenterology and Hepatology, Yale University School of Medicine, New Haven, Connecticut, United States. FAU - Fabbri, Carlo AU - Fabbri C AD - Gastroenterology and Digestive Endoscopy Unit, Forli-Cesena Hospitals, AUSL Romagna, Forli-Cesena, Italy. FAU - Binda, Cecilia AU - Binda C AUID- ORCID: 0000-0003-1148-9684 AD - Gastroenterology and Digestive Endoscopy Unit, Forli-Cesena Hospitals, AUSL Romagna, Forli-Cesena, Italy. FAU - Anderloni, Andrea AU - Anderloni A AD - Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy. FAU - Tarantino, Ilaria AU - Tarantino I AUID- ORCID: 0000-0001-8791-3395 AD - Endoscopy Service, Department of Diagnostic and Therapeutic Services, IRCCS - ISMETT, Palermo, Italy. FAU - Bejjani, Michael AU - Bejjani M AD - Department of Gastroenterology and Hepatology, Johns Hopkins Medicine, Baltimore, Maryland, United States. FAU - Ghandour, Bachir AU - Ghandour B AUID- ORCID: 0000-0002-7303-7504 AD - Department of Gastroenterology and Hepatology, Johns Hopkins Medicine, Baltimore, Maryland, United States. FAU - Singh, Vikesh AU - Singh V AD - Department of Gastroenterology and Hepatology, Johns Hopkins Medicine, Baltimore, Maryland, United States. FAU - Khashab, Mouen A AU - Khashab MA AD - Department of Gastroenterology and Hepatology, Johns Hopkins Medicine, Baltimore, Maryland, United States. LA - eng PT - Journal Article PT - Multicenter Study DEP - 20211214 PL - Germany TA - Endoscopy JT - Endoscopy JID - 0215166 RN - 0 (Metals) SB - IM MH - Drainage MH - Endosonography MH - Female MH - Humans MH - Male MH - Metals MH - Middle Aged MH - *Pancreatic Pseudocyst/complications/diagnostic imaging/surgery MH - Stents MH - Treatment Outcome MH - Ultrasonography, Interventional COIS- MA Al-Haddad receives teaching and research support from Boston Scientific. T Muniraj is a consultant for Boston Scientific. A Anderloni is a consultant for Boston Scientific. R Kunda is a consultant for Olympus, Boston Scientific, Ambu, Omega Medical Imaging and Apollo Endosurgery. V Singh is a consultant for Abbvie and Nestle Health Science and receives grant funding from Orgenesis and Theraly. M Khashab is a consultant for Boston Scientific, Olympus America, Medtronic and GI Supply. All other authors have no disclosures. EDAT- 2021/12/15 06:00 MHDA- 2022/07/01 06:00 CRDT- 2021/12/14 20:06 PHST- 2021/12/15 06:00 [pubmed] PHST- 2022/07/01 06:00 [medline] PHST- 2021/12/14 20:06 [entrez] AID - 10.1055/a-1682-7095 [doi] PST - ppublish SO - Endoscopy. 2022 Jul;54(7):706-711. doi: 10.1055/a-1682-7095. Epub 2021 Dec 14.