PMID- 34909604
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211217
IS  - 2573-2102 (Electronic)
IS  - 2573-2102 (Linking)
VI  - 5
IP  - 4
DP  - 2021 Oct
TI  - Hematology parameters as potential indicators of feed efficiency in pigs.
PG  - txab219
LID - 10.1093/tas/txab219 [doi]
LID - txab219
AB  - The identification of an inexpensive, indirect measure of feed efficiency in 
      swine could be a useful tool to help identify animals with improved phenotypes to 
      supplement expensive phenotypes including individual feed intakes. The purpose of 
      this study was to determine whether hematology parameters in pigs at the 
      beginning and end of a feed efficiency study, or changes in those values over the 
      study, were associated with average daily gain (ADG), average daily feed intake 
      (ADFI), or gain-to-feed (G:F). Whole blood samples were taken at days 0 and 42 
      from pigs (n = 178) that were monitored for individual feed intakes and body 
      weight gain during a 6-week study. Blood samples were analyzed for blood cell 
      parameters including white blood cell (WBC), neutrophil, lymphocyte, monocyte, 
      eosinophil and basophil counts, red blood cell (RBC) counts, hemoglobin, 
      hematocrit, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and 
      mean corpuscular hemoglobin concentration (MCHC), platelet count, and mean 
      platelet volume (MPV). Feed efficiency parameters were predicted using an ANOVA 
      model including fixed effects of farrowing group and pen (sex constant) and 
      individual hematology parameters at day 0, day 42 or their change as covariates. 
      At day 0, platelet count was positively associated with ADFI (P < 0.05) and 
      negatively associated with G:F (P < 0.1), and lymphocyte count was positively 
      associated with ADFI (P < 0.05). At day 42, neutrophil, RBC counts, hemoglobin 
      and hematocrit were associated with ADFI (P < 10(-3)). Over the course of the 
      study, changes in RBC measurements including RBC, hemoglobin, MCV, MCH, and MCHC 
      (P < 10(-4)) which may improve oxygen carrying capacity, were associated with ADG 
      and ADFI. The change in hematocrit over the course of the study was the only 
      parameter that was associated with all three measures of feed efficiency (P < 
      0.05). Changes in RBC parameters, especially hematocrit, may be useful 
      measurements to supplement feed efficiency phenotypes in swine.
CI  - Published by Oxford University Press on behalf of the American Society of Animal 
      Science 2021.
FAU - Lindholm-Perry, Amanda K
AU  - Lindholm-Perry AK
AD  - USDA, Agricultural Research Service, U.S. Meat Animal Research Center, Clay 
      Center, NE 68933, USA.
FAU - Kuehn, Larry A
AU  - Kuehn LA
AUID- ORCID: 0000-0002-7573-5365
AD  - USDA, Agricultural Research Service, U.S. Meat Animal Research Center, Clay 
      Center, NE 68933, USA.
FAU - Wells, James E
AU  - Wells JE
AD  - USDA, Agricultural Research Service, U.S. Meat Animal Research Center, Clay 
      Center, NE 68933, USA.
FAU - Rempel, Lea A
AU  - Rempel LA
AD  - USDA, Agricultural Research Service, U.S. Meat Animal Research Center, Clay 
      Center, NE 68933, USA.
FAU - Chitko-McKown, Carol G
AU  - Chitko-McKown CG
AD  - USDA, Agricultural Research Service, U.S. Meat Animal Research Center, Clay 
      Center, NE 68933, USA.
FAU - Keel, Brittney N
AU  - Keel BN
AD  - USDA, Agricultural Research Service, U.S. Meat Animal Research Center, Clay 
      Center, NE 68933, USA.
FAU - Oliver, William T
AU  - Oliver WT
AD  - USDA, Agricultural Research Service, U.S. Meat Animal Research Center, Clay 
      Center, NE 68933, USA.
LA  - eng
PT  - Journal Article
DEP - 20211119
PL  - England
TA  - Transl Anim Sci
JT  - Translational animal science
JID - 101738705
PMC - PMC8665215
OTO - NOTNLM
OT  - complete blood count
OT  - feed efficiency
OT  - pigs
OT  - red blood cells
EDAT- 2021/12/16 06:00
MHDA- 2021/12/16 06:01
PMCR- 2021/11/19
CRDT- 2021/12/15 12:33
PHST- 2021/08/30 00:00 [received]
PHST- 2021/11/17 00:00 [accepted]
PHST- 2021/12/15 12:33 [entrez]
PHST- 2021/12/16 06:00 [pubmed]
PHST- 2021/12/16 06:01 [medline]
PHST- 2021/11/19 00:00 [pmc-release]
AID - txab219 [pii]
AID - 10.1093/tas/txab219 [doi]
PST - epublish
SO  - Transl Anim Sci. 2021 Nov 19;5(4):txab219. doi: 10.1093/tas/txab219. eCollection 
      2021 Oct.