PMID- 34909822
OWN - NLM
STAT- MEDLINE
DCOM- 20211217
LR  - 20211217
IS  - 1678-2690 (Electronic)
IS  - 0001-3765 (Linking)
VI  - 93
IP  - suppl 4
DP  - 2021
TI  - Gender-related differences in the modulation of anthropometric, biochemical, and 
      immune markers by physical activity in hypertensive and diabetic individuals.
PG  - e20201905
LID - S0001-37652021000800606 [pii]
LID - 10.1590/0001-3765202120201905 [doi]
AB  - Systemic arterial hypertension (SAH) and type 2 diabetes mellitus (T2DM) compose 
      the two major noncommunicable chronic inflammatory diseases. Physical activity 
      has been shown as a promising complementary approach to control the systemic 
      inflammation. However, it is still unclear whether this modulation is 
      gender-dependent. The objective of this study was evaluate the gender-related 
      influence of physical activity on the inflammatory response and biochemical 
      profile of individuals with SAH and T2DM. An international physical activity 
      questionnaire was applied to 376 individuals diagnosed with SAH and T2DM in order 
      to access their exercises routine and was evaluated the influence of physical 
      activity in biochemical, anthropometrical, and immunological markers involved in 
      these disorders in men and women. Even though active individuals have exhibited 
      lower serum levels of IL-1beta, IFN-gamma, TNF-alpha, and IL-17A, the ratios between IL-10 
      and all inflammatory cytokines were higher in men than in women. Physically 
      active individuals also demonstrated increased HDL/LDL and HDL/VLDL ratios. 
      Moreover, multiple correlations revealed that in active women both IL-10 and 
      TNF-alpha serum levels positively correlate with fasting glucose levels, and were 
      negatively associated with HDL levels. Our findings suggest that gender-related 
      differences dictate a distinct crosstalk between inflammatory and biochemical 
      markers in physically active individuals.
FAU - Santos, Deborah C Dos
AU  - Santos DCD
AUID- ORCID: 0000-0003-4880-6014
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
FAU - Ribeiro, Israel S
AU  - Ribeiro IS
AUID- ORCID: 0000-0002-1262-1387
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
AD  - Universidade Federal do Sul da Bahia, Campus Paulo Freire, Praca Joana Angelica, 
      250, Sao Jose, 45988-058 Teixeira de Freitas, BA, Brazil.
FAU - Lopes, Diego Patrick S
AU  - Lopes DPS
AUID- ORCID: 0000-0002-9211-5758
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
FAU - Pereira, Italo S
AU  - Pereira IS
AUID- ORCID: 0000-0001-5697-5673
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
FAU - Santos, Denisar P
AU  - Santos DP
AUID- ORCID: 0000-0002-3930-9510
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
FAU - Muniz, Igor P R
AU  - Muniz IPR
AUID- ORCID: 0000-0003-1842-6432
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
FAU - Lima, Fernanda M DA Silva
AU  - Lima FMDS
AUID- ORCID: 0000-0001-9108-7831
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
FAU - Costa, Andressa Antonia S
AU  - Costa AAS
AUID- ORCID: 0000-0003-0079-7016
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
FAU - Souza, Daniela DA Silva P
AU  - Souza DDSP
AUID- ORCID: 0000-0001-6050-433X
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
FAU - Calado, Stefano Pedro DE Melo
AU  - Calado SPM
AUID- ORCID: 0000-0003-3458-1328
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
FAU - Goncalves, Caroline V
AU  - Goncalves CV
AUID- ORCID: 0000-0003-0895-1583
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
FAU - Galantini, Maria Poliana L
AU  - Galantini MPL
AUID- ORCID: 0000-0001-9423-5334
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
FAU - Lopes, Danilo N
AU  - Lopes DN
AUID- ORCID: 0000-0001-9473-9268
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
FAU - Silva, Robson A A DA
AU  - Silva RAAD
AUID- ORCID: 0000-0003-1361-1591
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
FAU - Santos, Gilvaneia S
AU  - Santos GS
AUID- ORCID: 0000-0002-5075-6872
AD  - Instituto Multidisciplinar em Saude, Campus Anisio Teixeira, Universidade Federal 
      da Bahia, Rua Hormindo Barros, 58, Bairro Candeias, 45.029-094 Vitoria da 
      Conquista, BA, Brazil.
LA  - eng
PT  - Journal Article
DEP - 20211208
PL  - Brazil
TA  - An Acad Bras Cienc
JT  - Anais da Academia Brasileira de Ciencias
JID - 7503280
RN  - 0 (Biomarkers)
SB  - IM
MH  - Biomarkers
MH  - *Diabetes Mellitus, Type 2
MH  - Exercise
MH  - Female
MH  - Humans
MH  - *Hypertension
MH  - Inflammation
MH  - Male
EDAT- 2021/12/16 06:00
MHDA- 2021/12/18 06:00
CRDT- 2021/12/15 12:38
PHST- 2020/12/10 00:00 [received]
PHST- 2021/09/06 00:00 [accepted]
PHST- 2021/12/15 12:38 [entrez]
PHST- 2021/12/16 06:00 [pubmed]
PHST- 2021/12/18 06:00 [medline]
AID - S0001-37652021000800606 [pii]
AID - 10.1590/0001-3765202120201905 [doi]
PST - epublish
SO  - An Acad Bras Cienc. 2021 Dec 8;93(suppl 4):e20201905. doi: 
      10.1590/0001-3765202120201905. eCollection 2021.