PMID- 34911089 OWN - NLM STAT- MEDLINE DCOM- 20220818 LR - 20220818 IS - 2193-6323 (Electronic) IS - 2193-6315 (Print) IS - 2193-6315 (Linking) VI - 83 IP - 5 DP - 2022 Sep TI - Surgical Treatment of Multilevel Degenerative Cervical Myelopathy: Open-Door Laminoplasty and Fixation via Unilateral Approach. A Feasibility Study. PG - 494-501 LID - 10.1055/s-0041-1739224 [doi] AB - OBJECTIVE: We compared open-door laminoplasty via a unilateral approach and additional unilateral lateral mass screw fixation (uLP) with laminectomy and bilateral lateral mass screw fixation (LC) in the surgical treatment of multilevel degenerative cervical myelopathy (mDCM). METHODS: A retrospective cohort analysis of 46 prospectively enrolled patients (23 uLP and 23 LC). The minimum follow-up was 1 year. Neck and arm pains were evaluated with visual analog scales and disability with the Neck Disability Index (NDI). Myelopathy was rated with the modified Japanese Orthopaedic Association (mJOA) score. Cervical sagittal parameters were measured on plain and functional X-ray films with a specific software. The statistical significance was set at p < 0.05. Fusion was defined as <2 degrees of intersegmental motion on flexion/extension radiographs. RESULTS: The two groups were similar in age and comorbidities. The mean operation time and the mean hospital stay were shorter in the uLP group (p = 0.015). The intraoperative blood loss did not exceed 200 mL in both groups. At follow-up, the groups showed comparable clinical outcome data. The sagittal profile did not deteriorate in either group. Fusion rates were 67% in the uLP group and 92% in the LC group. No infections occurred in either group. In the LC group, one patient developed a transient C5 palsy. Revision surgery was required for a malpositioned screw (LC) and for one implant failure (uLP). CONCLUSION: Laminoplasty and unilateral fixation via a unilateral approach achieved comparable clinical and radiologic results with laminectomy and bilateral fixation, despite a lower fusion rate. However, the surgical traumatization was less. CI - The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/). FAU - Schmeiser, Gregor AU - Schmeiser G AUID- ORCID: 0000-0002-2432-8276 AD - Department of Spine Surgery, Schoen-Klinik Hamburg-Eilbek, Hamburg, Germany. FAU - Bergmann, Janina Isabel AU - Bergmann JI AD - Department of Spine Surgery, Schoen-Klinik Hamburg-Eilbek, Hamburg, Germany. FAU - Papavero, Luca AU - Papavero L AUID- ORCID: 0000-0002-3664-8736 AD - Department of Spine Surgery, Schoen-Klinik Hamburg-Eilbek, Hamburg, Germany. FAU - Kothe, Ralph AU - Kothe R AD - Clinic for Spine Surgery, Schoen Clinic Hamburg Eilbek, Academic Hospital of the Eppendorf University Medical Center, Hamburg, Germany. LA - eng PT - Journal Article DEP - 20211215 PL - Germany TA - J Neurol Surg A Cent Eur Neurosurg JT - Journal of neurological surgery. Part A, Central European neurosurgery JID - 101580767 SB - IM MH - Cervical Vertebrae/diagnostic imaging/surgery MH - Feasibility Studies MH - Humans MH - Laminectomy/methods MH - *Laminoplasty/methods MH - Paralysis MH - Postoperative Complications/surgery MH - Retrospective Studies MH - *Spinal Cord Diseases/diagnostic imaging/surgery MH - Treatment Outcome PMC - PMC9381301 COIS- None declared. EDAT- 2021/12/16 06:00 MHDA- 2022/08/19 06:00 PMCR- 2021/12/01 CRDT- 2021/12/15 20:14 PHST- 2021/12/16 06:00 [pubmed] PHST- 2022/08/19 06:00 [medline] PHST- 2021/12/15 20:14 [entrez] PHST- 2021/12/01 00:00 [pmc-release] AID - 203018st [pii] AID - 10.1055/s-0041-1739224 [doi] PST - ppublish SO - J Neurol Surg A Cent Eur Neurosurg. 2022 Sep;83(5):494-501. doi: 10.1055/s-0041-1739224. Epub 2021 Dec 15.