PMID- 34911498
OWN - NLM
STAT- MEDLINE
DCOM- 20211217
LR  - 20211219
IS  - 1471-2415 (Electronic)
IS  - 1471-2415 (Linking)
VI  - 21
IP  - 1
DP  - 2021 Dec 15
TI  - Visual acuity and anatomical changes following vitrectomy for epiretinal membrane 
      foveoschisis: a case series.
PG  - 433
LID - 10.1186/s12886-021-02203-y [doi]
LID - 433
AB  - PURPOSE: To evaluate the visual outcome and macular anatomic structures on 
      spectral-domain optical coherence tomography (SD-OCT) of patients with epiretinal 
      membrane (ERM) foveoschisis who underwent vitrectomy. METHODS: A retrospective 
      cohort, interventional, case series. PARTICIPANTS: Fourteen patients (14 eyes) 
      with central vision loss from an ERM foveoschisis underwent vitrectomy at Chiang 
      Mai University Hospital from 2017 to 2018 and had a follow-up period of 
      12 months. INTERVENTIONS: The 23G vitrectomy with ERM and internal limiting 
      membrane (ILM) peeling was performed by a single surgeon. MAIN OUTCOMES: 
      Best-corrected visual acuity (BCVA) and anatomic appearance on SD-OCT were 
      assessed at the time of preoperative evaluations and post-operative follow-ups at 
      1, 3, 6, and 12 months. RESULTS: Fourteen patients with a mean (SD) age of 67.9 
      (7.9) years and a mean (SD) visual acuity (VA) of 0.6 (0.1) LogMAR units were 
      included in this study. Significant VA improvements were observed at the 3-month 
      (0.43 (0.14) LogMAR unit), 6-month (0.45 (0.16) LogMAR unit) and 12-month (0.37 
      (0.21) LogMAR unit) post-operative visits compared to baseline, all with P-values 
      < 0.001. At month 12, there were vision improvements of >/=3 lines in 8 (57.2%) 
      patients, vision improvements of 1 or 2 lines in 2 (14.3%) patients, vision 
      remained at the same line of pre-operation in 3 (21.4%) patients, and vision 
      decreased by 1 line in 1 (7.1%) patient. Regarding the anatomical outcomes, 13 
      (92.9%) patients achieved anatomical foveal restoration, while one had persistent 
      intraretinal schisis at the 12-month follow-up. The median time to achieve a 
      foveal restoration was 3 months. No significant visual impairments were observed 
      post-operatively. CONCLUSION: In patients with central vision loss from ERM 
      foveoschisis, vitrectomy with ILM stripping tended to improve both visual and 
      anatomical outcomes.
CI  - (c) 2021. The Author(s).
FAU - Photcharapongsakul, Chaiyaphot
AU  - Photcharapongsakul C
AD  - Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, 110 
      Intavaroros Road, Maung, Chiang Mai, 50200, Thailand.
FAU - Chokesuwattanaskul, Susama
AU  - Chokesuwattanaskul S
AD  - Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, 110 
      Intavaroros Road, Maung, Chiang Mai, 50200, Thailand.
FAU - Choovuthayakorn, Janejit
AU  - Choovuthayakorn J
AD  - Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, 110 
      Intavaroros Road, Maung, Chiang Mai, 50200, Thailand. janejit.c@cmu.ac.th.
FAU - Chaikitmongkol, Voraporn
AU  - Chaikitmongkol V
AD  - Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, 110 
      Intavaroros Road, Maung, Chiang Mai, 50200, Thailand.
FAU - Kunavisarut, Paradee
AU  - Kunavisarut P
AD  - Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, 110 
      Intavaroros Road, Maung, Chiang Mai, 50200, Thailand.
FAU - Watanachai, Nawat
AU  - Watanachai N
AD  - Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, 110 
      Intavaroros Road, Maung, Chiang Mai, 50200, Thailand.
FAU - Patikulsila, Direk
AU  - Patikulsila D
AD  - Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, 110 
      Intavaroros Road, Maung, Chiang Mai, 50200, Thailand.
LA  - eng
PT  - Journal Article
DEP - 20211215
PL  - England
TA  - BMC Ophthalmol
JT  - BMC ophthalmology
JID - 100967802
SB  - IM
MH  - Aged
MH  - Basement Membrane/surgery
MH  - *Epiretinal Membrane/surgery
MH  - Follow-Up Studies
MH  - Fovea Centralis
MH  - Humans
MH  - Retrospective Studies
MH  - Tomography, Optical Coherence
MH  - Visual Acuity
MH  - Vitrectomy
PMC - PMC8672529
OTO - NOTNLM
OT  - Anatomical outcomes
OT  - ERM Foveoschisis
OT  - Visual outcomes
COIS- The authors declare that they had no competing interest.
EDAT- 2021/12/17 06:00
MHDA- 2021/12/18 06:00
PMCR- 2021/12/15
CRDT- 2021/12/16 05:31
PHST- 2021/05/22 00:00 [received]
PHST- 2021/12/06 00:00 [accepted]
PHST- 2021/12/16 05:31 [entrez]
PHST- 2021/12/17 06:00 [pubmed]
PHST- 2021/12/18 06:00 [medline]
PHST- 2021/12/15 00:00 [pmc-release]
AID - 10.1186/s12886-021-02203-y [pii]
AID - 2203 [pii]
AID - 10.1186/s12886-021-02203-y [doi]
PST - epublish
SO  - BMC Ophthalmol. 2021 Dec 15;21(1):433. doi: 10.1186/s12886-021-02203-y.