PMID- 34912871 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20211217 IS - 2297-055X (Print) IS - 2297-055X (Electronic) IS - 2297-055X (Linking) VI - 8 DP - 2021 TI - Post-operative Atrial Fibrillation Impacts on Outcomes in Transcatheter and Surgical Aortic Valve Replacement. PG - 789548 LID - 10.3389/fcvm.2021.789548 [doi] LID - 789548 AB - Background: Atrial fibrillation (AF) in severe aortic stenosis (AS) has poor outcomes after transcatheter and surgical aortic valve replacement (TAVR and SAVR, respectively). We compared the incidence of AF after aortic valve replacement (AVR) according to the treatment method and the impact of AF on outcomes. Methods: We investigated the incidence of AF and clinical outcomes of AVR according to whether AF occurred after TAVR and SAVR after propensity score (PS)-matching for 1 year follow-up. Clinical outcomes were defined as death, stroke, and admission due to heart failure. The composite outcome comprised death, stroke, and admission due to heart failure. Results: A total of 221 patients with severe AS were enrolled consecutively, 100 of whom underwent TAVR and 121 underwent SAVR. The incidence of newly detected AF was significantly higher in the SAVR group before PS-matching (6.0 vs. 40.5%, P < 0.001) and after PS-matching (7.5 vs. 35.6%, P = 0.001). TAVR and SAVR showed no significant differences in outcomes except in terms of stroke. In the TAVR group, AF history did not affect the outcomes; however, in the SAVR group, AF history affected death (log rank P = 0.038). Post-AVR AF had a worse impact on admission due to heart failure (log rank P = 0.049) and composite outcomes in the SAVR group. Post-AVR AF had a worse impact on admission due to heart failure (log rank P = 0.008) and composite outcome in the TAVR group. Conclusion: Post-AVR AF could be considered as a predictor of the outcomes of AVR. TAVR might be a favorable treatment option for patients with severe symptomatic AS who are at high-risk for AF development or who have a history of AF because the occurrence of AF was more frequent in the SAVR group. CI - Copyright (c) 2021 Jeong, Yoon, Kim, Lee, Hyun, Kim, Lee, Jeong, Jeong, Yoon, Kim, Park, Ahn, Jeong and Cho. FAU - Jeong, Hyung Ki AU - Jeong HK AD - Division of Cardiology, Department of Internal Medicine, School of Medicine, Wonkwang University, Iksan, South Korea. AD - Division of Cardiology, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea. FAU - Yoon, Namsik AU - Yoon N AD - Division of Cardiology, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea. FAU - Kim, Ju Han AU - Kim JH AD - Division of Cardiology, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea. FAU - Lee, Nuri AU - Lee N AD - Division of Cardiology, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea. FAU - Hyun, Dae Yong AU - Hyun DY AD - Division of Cardiology, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea. FAU - Kim, Min Chul AU - Kim MC AD - Division of Cardiology, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea. FAU - Lee, Ki Hong AU - Lee KH AD - Division of Cardiology, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea. FAU - Jeong, Yo Cheon AU - Jeong YC AD - Department of Thoracic and Cardiovascular Surgery, Chonnam National University Medical School, Gwangju, South Korea. FAU - Jeong, In Seok AU - Jeong IS AD - Department of Thoracic and Cardiovascular Surgery, Chonnam National University Medical School, Gwangju, South Korea. FAU - Yoon, Hyun Ju AU - Yoon HJ AD - Division of Cardiology, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea. FAU - Kim, Kye Hun AU - Kim KH AD - Division of Cardiology, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea. FAU - Park, Hyung Wook AU - Park HW AD - Division of Cardiology, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea. FAU - Ahn, Youngkeun AU - Ahn Y AD - Division of Cardiology, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea. FAU - Jeong, Myung Ho AU - Jeong MH AD - Division of Cardiology, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea. FAU - Cho, Jeong Gwan AU - Cho JG AD - Division of Cardiology, Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea. LA - eng PT - Journal Article DEP - 20211129 PL - Switzerland TA - Front Cardiovasc Med JT - Frontiers in cardiovascular medicine JID - 101653388 PMC - PMC8667320 OTO - NOTNLM OT - aortic stenosis OT - atrial fibrillation OT - incidence OT - outcome OT - surgical aortic valve replacement OT - transcatheter aortic valve replacement COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2021/12/17 06:00 MHDA- 2021/12/17 06:01 PMCR- 2021/01/01 CRDT- 2021/12/16 06:36 PHST- 2021/10/05 00:00 [received] PHST- 2021/11/08 00:00 [accepted] PHST- 2021/12/16 06:36 [entrez] PHST- 2021/12/17 06:00 [pubmed] PHST- 2021/12/17 06:01 [medline] PHST- 2021/01/01 00:00 [pmc-release] AID - 10.3389/fcvm.2021.789548 [doi] PST - epublish SO - Front Cardiovasc Med. 2021 Nov 29;8:789548. doi: 10.3389/fcvm.2021.789548. eCollection 2021.