PMID- 3491590
OWN - NLM
STAT- MEDLINE
DCOM- 19870106
LR  - 20190628
IS  - 0003-4975 (Print)
IS  - 0003-4975 (Linking)
VI  - 42
IP  - 6
DP  - 1986 Dec
TI  - Combined valve and coronary artery bypass procedures in septuagenarians and 
      octogenarians: results in 120 patients.
PG  - 681-4
AB  - A consecutive series of 96 septuagenarians (mean age, 74) and 24 octogenarians 
      (mean age, 83) underwent coronary artery bypass (CAB) and valve operations using 
      hypothermia and hyperkalemic cardioplegia in a 45-month period; there was a mean 
      of 2.6 grafts per patient. Most patients were in New York Heart Association 
      (NYHA) class IV (57% of the septuagenarians and 88% of the octogenarians) 
      preoperatively. The early deaths were 19% for septuagenarians and 37% for 
      octogenarians; late deaths were 9% and 6%, respectively, after a mean of 25 
      months. Of 92 survivors, 78% of the septuagenarians and 87% of the octogenarians 
      improved by one or more NYHA class postoperatively. Of 58 patients with combined 
      CAB and aortic valve replacement, 12 (21%) died; of 38 with combined CAB and 
      mitral valve replacement 19 (50%) died; 2 of 9 (22%) with combined CAB and double 
      valve replacement died; and 2 of 11 (18%) with CAB and MV repair died. In 
      comparison, of patients with isolated valve replacement in the same period, 2 of 
      30 (7%) in the AVR group died, 5 of 17 (29%) died in the MVR group, 2 of 7 (33%) 
      in the DVR group died. The risk of combined valve procedures and bypass surgery 
      was significantly increased in the elderly and may warrant a less aggressive 
      procedure, especially in the mitral position.
FAU - Tsai, T P
AU  - Tsai TP
FAU - Matloff, J M
AU  - Matloff JM
FAU - Chaux, A
AU  - Chaux A
FAU - Kass, R M
AU  - Kass RM
FAU - Lee, M E
AU  - Lee ME
FAU - Czer, L S
AU  - Czer LS
FAU - DeRobertis, M A
AU  - DeRobertis MA
FAU - Gray, R J
AU  - Gray RJ
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Ann Thorac Surg
JT  - The Annals of thoracic surgery
JID - 15030100R
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Aortic Valve/surgery
MH  - *Coronary Artery Bypass
MH  - Coronary Disease/mortality/surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Septal Defects, Atrial/mortality/surgery
MH  - Heart Valve Diseases/mortality/surgery
MH  - *Heart Valve Prosthesis
MH  - Humans
MH  - Male
MH  - Mitral Valve/surgery
MH  - Postoperative Complications/epidemiology/mortality
MH  - Risk
EDAT- 1986/12/01 00:00
MHDA- 1986/12/01 00:01
CRDT- 1986/12/01 00:00
PHST- 1986/12/01 00:00 [pubmed]
PHST- 1986/12/01 00:01 [medline]
PHST- 1986/12/01 00:00 [entrez]
AID - S0003-4975(10)64608-5 [pii]
AID - 10.1016/s0003-4975(10)64608-5 [doi]
PST - ppublish
SO  - Ann Thorac Surg. 1986 Dec;42(6):681-4. doi: 10.1016/s0003-4975(10)64608-5.