PMID- 34917790
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211218
IS  - 2405-8440 (Print)
IS  - 2405-8440 (Electronic)
IS  - 2405-8440 (Linking)
VI  - 7
IP  - 12
DP  - 2021 Dec
TI  - Detection and quantification of multiclass antibiotic residues in poultry 
      products using solid-phase extraction and high-performance liquid chromatography 
      with diode array detection.
PG  - e08469
LID - 10.1016/j.heliyon.2021.e08469 [doi]
LID - e08469
AB  - This article describes the initial study on the simultaneous determination of 
      multiclass antibiotic residues in imported and local frozen poultry specimens, 
      including turkey gizzard and muscle tissues, and chicken muscle tissues, commonly 
      consumed in Ogun State, Nigeria. Minced tissues were treated with phosphate 
      buffer adjusted to pH 7 that was cleaned using C18 SPE-column (Supelclean) 
      cartridge. For the determination of six antibiotic residues including 
      fluoroquinolones, sulfonamides, and macrolides, a solid-phase extraction method 
      was used, followed by extract analysis using high-performance liquid 
      chromatography-diode array detection (HPLC-DAD). The coefficient of determination 
      (R(2)) for the external standards for all the analytes ranged between 0.963 and 
      0.999. The limit of detection (LOD) and quantification (LOQ) ranged between 5.37 
      - 55.4 mug/kg, and 17.9-185 mug/kg, respectively. Enrofloxacin, sulfadimethoxine, 
      sulfamerazine, and tylosin showed high concentration levels in the frozen poultry 
      beyond acceptable maximum residue limits (MRLs). The six drugs considered in this 
      study were present at higher concentrations in domestic chicken tissues than the 
      permissible level. This suggests that farmers do not observe the cessation period 
      before poultry birds previously treated with antibiotics are sold to consumers 
      thus exposing them to potentially hazardous antibiotic residues.
CI  - (c) 2021 The Author(s).
FAU - Oyedeji, Abdulrasaq O
AU  - Oyedeji AO
AD  - Department of Science Laboratory Technology, The Federal Polytechnic, Ilaro, 
      Nigeria.
FAU - Msagati, Titus A M
AU  - Msagati TAM
AD  - Institute for Nanotechnology and Water Sustainability, College of Science 
      Engineering and Technology, University of South Africa, Roodepoort, South Africa.
FAU - Williams, Akan B
AU  - Williams AB
AD  - Department of Chemistry, Covenant University, Ota, Ogun State, Nigeria.
FAU - Benson, Nsikak U
AU  - Benson NU
AD  - Department of Chemistry, Covenant University, Ota, Ogun State, Nigeria.
LA  - eng
PT  - Journal Article
DEP - 20211124
PL  - England
TA  - Heliyon
JT  - Heliyon
JID - 101672560
PMC - PMC8646174
OTO - NOTNLM
OT  - Antibiotic residues
OT  - Food contamination
OT  - High-performance liquid chromatography
OT  - Poultry tissues
OT  - Solid-phase extraction
COIS- The authors declare no conflict of interest.
EDAT- 2021/12/18 06:00
MHDA- 2021/12/18 06:01
PMCR- 2021/11/24
CRDT- 2021/12/17 07:02
PHST- 2021/05/30 00:00 [received]
PHST- 2021/09/19 00:00 [revised]
PHST- 2021/11/19 00:00 [accepted]
PHST- 2021/12/17 07:02 [entrez]
PHST- 2021/12/18 06:00 [pubmed]
PHST- 2021/12/18 06:01 [medline]
PHST- 2021/11/24 00:00 [pmc-release]
AID - S2405-8440(21)02572-X [pii]
AID - e08469 [pii]
AID - 10.1016/j.heliyon.2021.e08469 [doi]
PST - epublish
SO  - Heliyon. 2021 Nov 24;7(12):e08469. doi: 10.1016/j.heliyon.2021.e08469. 
      eCollection 2021 Dec.