PMID- 34926566 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20211221 IS - 2296-875X (Print) IS - 2296-875X (Electronic) IS - 2296-875X (Linking) VI - 8 DP - 2021 TI - Comparison of Clinical Efficacy and Safety Between da Vinci Robotic and Laparoscopic Intersphincteric Resection for Low Rectal Cancer: A Meta-Analysis. PG - 752009 LID - 10.3389/fsurg.2021.752009 [doi] LID - 752009 AB - Background and Aims: The intersphincteric resection (ISR) is beneficial for saving patients' anus to a large extent and restoring original bowel continuity. Laparoscopic ISR (L-ISR) has its drawbacks, such as two-dimensional images, low motion flexibility, and unstable lens. Recently, da Vinci robotic ISR (R-ISR) is increasingly used worldwide. The purpose of this article is to compare the feasibility, safety, oncological outcomes, and clinical efficacy of R-ISR vs. L-ISR for low rectal cancer. Methods: PubMed, EMBASE, Cochrane Library, and Web of Science were searched to identify comparative studies of R-ISR vs. L-ISR. Demographic, clinical, and outcome data were extracted. Mean difference (MD) and risk ratio (RR) with their corresponding confidence intervals (CIs) were calculated. Results: Five studies were included. In total, 510 patients were included, of whom 273 underwent R-ISR and 237 L-ISR. Compared with L-ISR, R-ISR has significantly lower estimated intraoperative blood loss (MD = -23.31, 95% CI [-41.98, -4.64], P = 0.01), longer operative time (MD = 51.77, 95% CI [25.68, 77.86], P = 0.0001), hospitalization days (MD = -1.52, 95% CI [-2.10, 0.94], P < 0.00001), and postoperative urinary complications (RR = 0.36, 95% CI [0.16, 0.82], P = 0.02). Conclusions: The potential benefits of R-ISR are considered as a safe and feasible alternative choice for the treatment of low rectal tumors. CI - Copyright (c) 2021 Zhang, Qi, Yi, Cao, Gao and Zhang. FAU - Zhang, Jie AU - Zhang J AD - Department of General Surgery, General Hospital of Northern Theater Command (Formerly Called General Hospital of Shenyang Military Area), Shenyang, China. AD - Postgraduate College, Dalian Medical University, Dalian, China. FAU - Qi, Xingshun AU - Qi X AD - Department of Gastroenterology, General Hospital of Northern Theater Command (Formerly Called General Hospital of Shenyang Military Area), Shenyang, China. FAU - Yi, Fangfang AU - Yi F AD - Postgraduate College, Dalian Medical University, Dalian, China. AD - Department of Gastroenterology, General Hospital of Northern Theater Command (Formerly Called General Hospital of Shenyang Military Area), Shenyang, China. FAU - Cao, Rongrong AU - Cao R AD - Department of Gastroenterology, General Hospital of Northern Theater Command (Formerly Called General Hospital of Shenyang Military Area), Shenyang, China. AD - Postgraduate College, Jinzhou Medical University, Jinzhou, China. FAU - Gao, Guangrong AU - Gao G AD - Department of General Surgery, General Hospital of Northern Theater Command (Formerly Called General Hospital of Shenyang Military Area), Shenyang, China. FAU - Zhang, Cheng AU - Zhang C AD - Department of General Surgery, General Hospital of Northern Theater Command (Formerly Called General Hospital of Shenyang Military Area), Shenyang, China. LA - eng PT - Systematic Review DEP - 20211202 PL - Switzerland TA - Front Surg JT - Frontiers in surgery JID - 101645127 PMC - PMC8674929 OTO - NOTNLM OT - clinical efficacy OT - da Vinci robot OT - intersphincteric resection OT - laparoscope OT - low rectal cancer COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2021/12/21 06:00 MHDA- 2021/12/21 06:01 PMCR- 2021/12/02 CRDT- 2021/12/20 06:18 PHST- 2021/08/02 00:00 [received] PHST- 2021/11/02 00:00 [accepted] PHST- 2021/12/20 06:18 [entrez] PHST- 2021/12/21 06:00 [pubmed] PHST- 2021/12/21 06:01 [medline] PHST- 2021/12/02 00:00 [pmc-release] AID - 10.3389/fsurg.2021.752009 [doi] PST - epublish SO - Front Surg. 2021 Dec 2;8:752009. doi: 10.3389/fsurg.2021.752009. eCollection 2021.