PMID- 34940006
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211226
IS  - 2039-7275 (Print)
IS  - 2039-7283 (Electronic)
IS  - 2039-7275 (Linking)
VI  - 11
IP  - 4
DP  - 2021 Dec 6
TI  - Clinical Characteristics, Treatment, and Short-Term Outcome in Patients with 
      Heart Failure and Cancer.
PG  - 933-941
LID - 10.3390/clinpract11040107 [doi]
AB  - (1) Our study aimed to look at the clinical characteristics, treatment and 
      short-term outcomes of patients hospitalized due to heart failure with coexisting 
      cancer. (2) Methods: Seventy one cancer (Ca) patients and a randomly selected 70 
      patients without Ca, hospitalized due to heart failure exacerbation in the same 
      time period constituted the study group (Ca patient group) and controls (non-Ca 
      group), respectively. Data on clinical characteristics were collected 
      retrospectively for both groups. (3) Results: Cancer patients presented with a 
      less advanced NYHA class, had more frequent HFpEF, a higher peak troponin T 
      level, and smaller left atrium size, as compared with controls. The in-hospital 
      deaths of Ca patients were associated with: a higher New York Heart Association 
      (NYHA) class, lower HgB level, worse renal function, higher K and AST levels, 
      presence of diabetes mellitus, and HFpEF. By multivariate logistic regression 
      analysis, impaired renal function was the only independent predictor of 
      in-hospital death in Ca patients (OR-1.15; CI 1.05; 1.27); p = 0.017). The 
      following covariates entered the regression: NYHA class, HgB, GFR, K(+), AST, 
      diabetes mellitus t.2, and HFpEF. (4) Conclusions: The clinical picture and the 
      course of heart failure in patients with and without cancer are different.
FAU - Piotrowski, Jedrzej
AU  - Piotrowski J
AD  - Medical Faculty, Medical University of Lodz, 90-419 Lodz, Poland.
FAU - Timler, Malgorzata
AU  - Timler M
AD  - Department of Management and Logistics in Healthcare, Medical University of Lodz, 
      90-419 Lodz, Poland.
FAU - Kozlowski, Remigiusz
AU  - Kozlowski R
AUID- ORCID: 0000-0003-2781-5341
AD  - Department of Emergency Medicine and Disaster Medicine, Medical University of 
      Lodz, 92-212 Lodz, Poland.
FAU - Stasiak, Arkadiusz
AU  - Stasiak A
AUID- ORCID: 0000-0002-7953-4739
AD  - Department of Physiology, Development and Neuroscience, University of Cambridge, 
      Cambridge CB3 9BB, UK.
FAU - Stasiak, Joanna
AU  - Stasiak J
AD  - Department of Chemical Engineering and Biotechnology, University of Cambridge, 
      Cambridge CB3 9BB, UK.
FAU - Bissinger, Andrzej
AU  - Bissinger A
AD  - Cardiooncology Department, Medical University of Lodz, 90-647 Lodz, Poland.
FAU - Timler, Dariusz
AU  - Timler D
AUID- ORCID: 0000-0002-5415-5660
AD  - Department of Emergency Medicine and Disaster Medicine, Medical University of 
      Lodz, 92-212 Lodz, Poland.
FAU - Timler, Wojciech
AU  - Timler W
AD  - Department of Emergency Medicine and Disaster Medicine, Medical University of 
      Lodz, 92-212 Lodz, Poland.
FAU - Marczak, Michal
AU  - Marczak M
AD  - Department of Management and Logistics in Healthcare, Medical University of Lodz, 
      90-419 Lodz, Poland.
FAU - Zaluska, Roman
AU  - Zaluska R
AUID- ORCID: 0000-0001-6408-3843
AD  - Department of Management and Logistics in Healthcare, Medical University of Lodz, 
      90-419 Lodz, Poland.
FAU - Piotrowski, Grzegorz
AU  - Piotrowski G
AD  - Cardiooncology Department, Medical University of Lodz, 90-647 Lodz, Poland.
AD  - Cardiology Department, Nicolaus Copernicus Memorial Hospital, 93-513 Lodz, 
      Poland.
LA  - eng
PT  - Journal Article
DEP - 20211206
PL  - Switzerland
TA  - Clin Pract
JT  - Clinics and practice
JID - 101563282
PMC - PMC8700386
OTO - NOTNLM
OT  - cancer
OT  - heart failure
OT  - short-term outcome
OT  - treatment
COIS- The authors declare no conflict of interest.
EDAT- 2021/12/24 06:00
MHDA- 2021/12/24 06:01
PMCR- 2021/12/06
CRDT- 2021/12/23 12:41
PHST- 2021/09/29 00:00 [received]
PHST- 2021/11/18 00:00 [revised]
PHST- 2021/11/29 00:00 [accepted]
PHST- 2021/12/23 12:41 [entrez]
PHST- 2021/12/24 06:00 [pubmed]
PHST- 2021/12/24 06:01 [medline]
PHST- 2021/12/06 00:00 [pmc-release]
AID - clinpract11040107 [pii]
AID - clinpract-11-00107 [pii]
AID - 10.3390/clinpract11040107 [doi]
PST - epublish
SO  - Clin Pract. 2021 Dec 6;11(4):933-941. doi: 10.3390/clinpract11040107.