PMID- 34944629
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211229
IS  - 2227-9059 (Print)
IS  - 2227-9059 (Electronic)
IS  - 2227-9059 (Linking)
VI  - 9
IP  - 12
DP  - 2021 Dec 2
TI  - The Most Relevant Factors Affecting the Perioperative Death Rate in Patients with 
      Acute Coronary Syndrome and COVID-19, Based on Annual Follow-Up in the ORPKI 
      Registry.
LID - 10.3390/biomedicines9121813 [doi]
LID - 1813
AB  - BACKGROUND: The COVID-19 pandemic is significantly affecting the functioning of 
      the entire healthcare system. The disease itself may be associated with 
      thromboembolic complications. The purpose of this study is to compare patients 
      with acute coronary syndrome (ACS) and patients with ACS who were diagnosed with 
      COVID-19 in terms of their clinical profile, management, treatment complications, 
      and prognosis. METHODS: We analyzed 47,940 cases of patients treated for ACS in 
      2020, including 44,952 patients (93.8%) who were not diagnosed with COVID-19 and 
      2988 patients (6.2%) who tested positive for COVID-19. RESULTS: Patients with 
      COVID-19 were significantly more likely to experience out-of-hospital sudden 
      cardiac arrest (7.9 vs. 1.1%; p < 0.0001) and be transported directly to a 
      catheterization laboratory (21.3% vs. 8.1%; p < 0.0001). Mortality was 
      significantly higher in this group (0.9% vs. 0.4%; p < 0.0001). The risk of 
      perioperative death was increased by age over 65 years, use of glycoprotein 
      IIb/IIIa inhibitors (GPI IIb/IIIa), femoral access, critical left main stem 
      coronary artery (LMCA) vascular lesions, ST elevation myocardial infarction 
      (STEMI), and no-reflow phenomenon. CONCLUSIONS: Despite the pandemic, patients 
      with COVID-19 were treated equally to healthy patients. Efficient organization of 
      the healthcare system allowed the prompt transportation of patients to 
      catheterization laboratories. The study group was characterized by a worse 
      prognosis that was affected by multiple factors.
FAU - Kazirod-Wolski, Karol
AU  - Kazirod-Wolski K
AUID- ORCID: 0000-0001-8407-2527
AD  - Collegium Medicum, Jan Kochanowski University in Kielce, 25-369 Kielce, Poland.
FAU - Sielski, Janusz
AU  - Sielski J
AD  - Collegium Medicum, Jan Kochanowski University in Kielce, 25-369 Kielce, Poland.
FAU - Sidlo, Jacek
AU  - Sidlo J
AUID- ORCID: 0000-0002-2271-1466
AD  - Collegium Medicum, Jan Kochanowski University in Kielce, 25-369 Kielce, Poland.
FAU - Januszek, Rafal
AU  - Januszek R
AUID- ORCID: 0000-0002-6591-1919
AD  - Department of Cardiology and Cardiovascular Interventions, University Hospital, 2 
      Jakubowskiego Street, 30-688 Krakow, Poland.
AD  - Second Department of Cardiology, Faculty of Medicine, Institute of Cardiology, 
      Medical College, Jagiellonian University, 30-688 Krakow, Poland.
FAU - Siudak, Zbigniew
AU  - Siudak Z
AD  - Collegium Medicum, Jan Kochanowski University in Kielce, 25-369 Kielce, Poland.
LA  - eng
GR  - SUPB.RN.21.126/Jan Kochanowski University/
PT  - Journal Article
DEP - 20211202
PL  - Switzerland
TA  - Biomedicines
JT  - Biomedicines
JID - 101691304
PMC - PMC8698975
OTO - NOTNLM
OT  - COVID-19
OT  - STEMI
OT  - acute coronary syndrome
COIS- The authors declare no conflict of interest.
EDAT- 2021/12/25 06:00
MHDA- 2021/12/25 06:01
PMCR- 2021/12/02
CRDT- 2021/12/24 01:06
PHST- 2021/11/10 00:00 [received]
PHST- 2021/11/26 00:00 [revised]
PHST- 2021/11/29 00:00 [accepted]
PHST- 2021/12/24 01:06 [entrez]
PHST- 2021/12/25 06:00 [pubmed]
PHST- 2021/12/25 06:01 [medline]
PHST- 2021/12/02 00:00 [pmc-release]
AID - biomedicines9121813 [pii]
AID - biomedicines-09-01813 [pii]
AID - 10.3390/biomedicines9121813 [doi]
PST - epublish
SO  - Biomedicines. 2021 Dec 2;9(12):1813. doi: 10.3390/biomedicines9121813.