PMID- 34945093
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211229
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 10
IP  - 24
DP  - 2021 Dec 11
TI  - Autoimmune Diseases of Digestive Organs-A Multidisciplinary Challenge: A Focus on 
      Hepatopancreatobiliary Manifestation.
LID - 10.3390/jcm10245796 [doi]
LID - 5796
AB  - It is well known that some pathological conditions, especially of autoimmune 
      etiology, are associated with the HLA (human leukocyte antigen) phenotype. Among 
      these diseases, we include celiac disease, inflammatory bowel disease, autoimmune 
      enteropathy, autoimmune hepatitis, primary sclerosing cholangitis and primary 
      biliary cholangitis. Immunoglobulin G4-related diseases (IgG4-related diseases) 
      constitute a second group of autoimmune gastrointestinal, hepatobiliary and 
      pancreatic illnesses. IgG4-related diseases are systemic and rare autoimmune 
      illnesses. They often are connected with chronic inflammation and fibrotic 
      reaction that can occur in any organ of the body. The most typical feature of 
      these diseases is a mononuclear infiltrate with IgG4-positive plasma cells and 
      self-sustaining inflammatory response. In this review, we focus especially upon 
      the hepatopancreatobiliary system, autoimmune pancreatitis and IgG4-related 
      sclerosing cholangitis. The cooperation of the gastroenterologist, radiologist, 
      surgeon and histopathologist is crucial for establishing correct diagnoses and 
      appropriate treatment, especially in IgG4 hepatopancreatobiliary diseases.
FAU - Kunovsky, Lumir
AU  - Kunovsky L
AUID- ORCID: 0000-0003-2985-8759
AD  - Department of Gastroenterology and Internal Medicine, University Hospital Brno, 
      625 00 Brno, Czech Republic.
AD  - Department of Surgery, University Hospital Brno, 625 00 Brno, Czech Republic.
AD  - Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
FAU - Dite, Petr
AU  - Dite P
AD  - Department of Gastroenterology and Internal Medicine, University Hospital Brno, 
      625 00 Brno, Czech Republic.
AD  - Department of Gastroenterology and Internal Medicine, University Hospital 
      Ostrava, 728 00 Ostrava, Czech Republic.
AD  - Faculty of Medicine, University of Ostrava, 703 00 Ostrava, Czech Republic.
FAU - Jabandziev, Petr
AU  - Jabandziev P
AUID- ORCID: 0000-0002-4094-2364
AD  - Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
AD  - Department of Pediatrics, University Hospital Brno, 613 00 Brno, Czech Republic.
AD  - Central European Institute of Technology, Masaryk University, 625 00 Brno, Czech 
      Republic.
FAU - Kala, Zdenek
AU  - Kala Z
AD  - Department of Surgery, University Hospital Brno, 625 00 Brno, Czech Republic.
AD  - Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
FAU - Vaculova, Jitka
AU  - Vaculova J
AUID- ORCID: 0000-0002-7998-772X
AD  - Department of Gastroenterology and Internal Medicine, University Hospital Brno, 
      625 00 Brno, Czech Republic.
AD  - Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
FAU - Andrasina, Tomas
AU  - Andrasina T
AUID- ORCID: 0000-0001-5723-5175
AD  - Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
AD  - Department of Radiology and Nuclear Medicine, University Hospital Brno, 625 00 
      Brno, Czech Republic.
FAU - Hrunka, Matej
AU  - Hrunka M
AUID- ORCID: 0000-0002-8154-1567
AD  - Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
AD  - Department of Pediatrics, University Hospital Brno, 613 00 Brno, Czech Republic.
FAU - Bojkova, Martina
AU  - Bojkova M
AD  - Department of Gastroenterology and Internal Medicine, University Hospital 
      Ostrava, 728 00 Ostrava, Czech Republic.
AD  - Faculty of Medicine, University of Ostrava, 703 00 Ostrava, Czech Republic.
FAU - Trna, Jan
AU  - Trna J
AUID- ORCID: 0000-0003-3138-9736
AD  - Department of Gastroenterology and Internal Medicine, University Hospital Brno, 
      625 00 Brno, Czech Republic.
AD  - Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
AD  - Department of Gastroenterology and Digestive Endoscopy, Masaryk Memorial Cancer 
      Institute, 602 00 Brno, Czech Republic.
LA  - eng
GR  - FNBr, 65269705, Sup 3/21/Ministry of Health/
GR  - NU20-03-00126/Ministry of Health/
PT  - Journal Article
PT  - Review
DEP - 20211211
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC8705412
OTO - NOTNLM
OT  - IgG4-related hepatopathy
OT  - IgG4-related sclerosing cholangitis
OT  - autoimmune hepatitis
OT  - autoimmune pancreatitis
OT  - celiac disease
OT  - human leukocyte antigen
OT  - inflammatory bowel disease
OT  - primary biliary cholangitis
OT  - primary sclerosing cholangitis
COIS- The authors declare no conflict of interest.
EDAT- 2021/12/25 06:00
MHDA- 2021/12/25 06:01
PMCR- 2021/12/11
CRDT- 2021/12/24 01:07
PHST- 2021/10/26 00:00 [received]
PHST- 2021/12/04 00:00 [revised]
PHST- 2021/12/07 00:00 [accepted]
PHST- 2021/12/24 01:07 [entrez]
PHST- 2021/12/25 06:00 [pubmed]
PHST- 2021/12/25 06:01 [medline]
PHST- 2021/12/11 00:00 [pmc-release]
AID - jcm10245796 [pii]
AID - jcm-10-05796 [pii]
AID - 10.3390/jcm10245796 [doi]
PST - epublish
SO  - J Clin Med. 2021 Dec 11;10(24):5796. doi: 10.3390/jcm10245796.