PMID- 34946402
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211229
IS  - 2227-9032 (Print)
IS  - 2227-9032 (Electronic)
IS  - 2227-9032 (Linking)
VI  - 9
IP  - 12
DP  - 2021 Dec 3
TI  - Health Utilities in Patients with Type 2 Diabetes in Taiwan.
LID - 10.3390/healthcare9121672 [doi]
LID - 1672
AB  - We aimed to measure health utilities in patients with diabetes mellitus (DM) in 
      Taiwan and to estimate the impact of common DM-related complications and adverse 
      effects (AEs) on health utilities. The present study was a cross-sectional survey 
      of DM patients at a metropolitan hospital. Respondents' health-related quality of 
      life (HRQoL) was assessed by the EQ-5D-5L, and ordinary least-squares (OLS) 
      regression was used to estimate the impact of self-reported DM-related 
      complications and AEs on health utilities after controlling for age, gender, and 
      duration of DM. A total of 506 eligible adults with type 2 DM (T2DM) were 
      enrolled. The EQ-5D index values in our study sample ranged from -0.13 to 1, with 
      a mean +/- standard deviation of 0.88 +/- 0.20. As indicated by the negative 
      regression coefficients, the presence of any complication or AE was associated 
      with lower EQ-5D index values, and the greatest impact on the score was made by 
      amputation (-0.276), followed by stroke (-0.211), and blindness (-0.203). In 
      conclusion, the present study elicited health utilities in patients with T2DM in 
      Taiwan using the EQ-5D-5L. These estimated utility decrements provided essential 
      data for future DM cost-utility analyses that are needed as a result of the 
      increasing prevalence and health expenditures of DM.
FAU - Chen, Chia-Chia
AU  - Chen CC
AUID- ORCID: 0000-0001-9875-5310
AD  - Department of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 
      11031, Taiwan.
FAU - Chen, Jin-Hua
AU  - Chen JH
AD  - Graduate Institute of Data Science, College of Management, Taipei Medical 
      University, Taipei 11031, Taiwan.
AD  - Statistics Center, Office of Data Science, Taipei Medical University, Taipei 
      11031, Taiwan.
FAU - Chen, Chien-Lung
AU  - Chen CL
AD  - Division of Nephrology, Landseed International Hospital, Taoyuan 32449, Taiwan.
FAU - Lai, Tzu-Jung
AU  - Lai TJ
AD  - Center for Drug Evaluation, Taipei 11557, Taiwan.
FAU - Ko, Yu
AU  - Ko Y
AUID- ORCID: 0000-0003-4199-0867
AD  - Department of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 
      11031, Taiwan.
AD  - Research Center for Pharmacoeconomics, College of Pharmacy, Taipei Medical 
      University, Taipei 11031, Taiwan.
LA  - eng
GR  - RC1051115/Center for Drug Evaluation, Taiwan/
PT  - Journal Article
DEP - 20211203
PL  - Switzerland
TA  - Healthcare (Basel)
JT  - Healthcare (Basel, Switzerland)
JID - 101666525
PMC - PMC8701244
OTO - NOTNLM
OT  - DM complications
OT  - EQ-5D
OT  - diabetes mellitus
OT  - health utilities
COIS- The authors declare no conflict of interest.
EDAT- 2021/12/25 06:00
MHDA- 2021/12/25 06:01
PMCR- 2021/12/03
CRDT- 2021/12/24 01:11
PHST- 2021/11/08 00:00 [received]
PHST- 2021/11/26 00:00 [revised]
PHST- 2021/11/30 00:00 [accepted]
PHST- 2021/12/24 01:11 [entrez]
PHST- 2021/12/25 06:00 [pubmed]
PHST- 2021/12/25 06:01 [medline]
PHST- 2021/12/03 00:00 [pmc-release]
AID - healthcare9121672 [pii]
AID - healthcare-09-01672 [pii]
AID - 10.3390/healthcare9121672 [doi]
PST - epublish
SO  - Healthcare (Basel). 2021 Dec 3;9(12):1672. doi: 10.3390/healthcare9121672.