PMID- 34948479 OWN - NLM STAT- MEDLINE DCOM- 20211231 LR - 20240404 IS - 1660-4601 (Electronic) IS - 1661-7827 (Print) IS - 1660-4601 (Linking) VI - 18 IP - 24 DP - 2021 Dec 7 TI - Comparison of Content and Quality of Caribbean, International, and High-Income Country-Specific Clinical Guidelines for Managing Type 2 Diabetes Mellitus. LID - 10.3390/ijerph182412868 [doi] LID - 12868 AB - PURPOSE: Type 2 diabetes mellitus (T2DM) is poorly managed in the Caribbean region; therefore, conducting an assessment on the content and quality of clinical guidelines could assist guideline developers in detecting and addressing information gaps. Hence, this study aimed to benchmark and compare the clinical guidelines for T2DM management from the Caribbean to guidelines developed internationally and by high-income countries. METHODS: Seven T2DM management clinical guidelines were a priori selected from international and high-income country-specific clinical guidelines and then compared to the country-specific T2DM management clinical guidelines of the Caribbean region. Two reviewers independently assessed content (using a previously piloted data extraction form) and quality using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) tool. RESULTS: The Caribbean clinical guideline was found to contain similar levels of T2DM management topics when compared to international and high-income country-specific clinical guidelines; however, one country-specific clinical guideline from New Zealand was found to have substantially lower levels of content. The clinical guideline from the Caribbean was found to be of low quality and could not be used in practice; however, only three comparator clinical guidelines were found to be of high quality and could be recommended for use in clinical practice. A further three comparator clinical guidelines could be used in practice with minor modifications. CONCLUSION: Although the T2DM management clinical guidelines from the Caribbean region contained high levels of content with regards to relevant topics, it was of insufficient quality to be used in clinical practice. Therefore, an alternative high-quality clinical guideline, as identified within this study, should be adopted and used within the Caribbean region to manage T2DM until a high-quality region-specific clinical guideline can be developed. FAU - Nixon, Amy Latifah AU - Nixon AL AUID- ORCID: 0000-0002-2968-1079 AD - Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham NG7 2RD, UK. AD - The Nottingham Centre for Evidence-Based Healthcare, A Joanna Briggs Institute Centre of Excellence, University of Nottingham, Nottingham NG7 2RD, UK. FAU - Chattopadhyay, Kaushik AU - Chattopadhyay K AUID- ORCID: 0000-0002-3235-8168 AD - Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham NG7 2RD, UK. AD - The Nottingham Centre for Evidence-Based Healthcare, A Joanna Briggs Institute Centre of Excellence, University of Nottingham, Nottingham NG7 2RD, UK. FAU - Leonardi-Bee, Jo AU - Leonardi-Bee J AD - Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham NG7 2RD, UK. AD - The Nottingham Centre for Evidence-Based Healthcare, A Joanna Briggs Institute Centre of Excellence, University of Nottingham, Nottingham NG7 2RD, UK. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review DEP - 20211207 PL - Switzerland TA - Int J Environ Res Public Health JT - International journal of environmental research and public health JID - 101238455 SB - IM MH - Benchmarking MH - Caribbean Region MH - *Diabetes Mellitus, Type 2/therapy MH - Humans MH - New Zealand PMC - PMC8702176 OTO - NOTNLM OT - Caribbean OT - clinical guidelines OT - high-income countries OT - improved outcomes OT - international OT - management OT - type 2 diabetes mellitus COIS- The authors have no conflicts of interest to declare. EDAT- 2021/12/25 06:00 MHDA- 2022/01/01 06:00 PMCR- 2021/12/07 CRDT- 2021/12/24 01:18 PHST- 2021/10/12 00:00 [received] PHST- 2021/11/30 00:00 [revised] PHST- 2021/12/01 00:00 [accepted] PHST- 2021/12/24 01:18 [entrez] PHST- 2021/12/25 06:00 [pubmed] PHST- 2022/01/01 06:00 [medline] PHST- 2021/12/07 00:00 [pmc-release] AID - ijerph182412868 [pii] AID - ijerph-18-12868 [pii] AID - 10.3390/ijerph182412868 [doi] PST - epublish SO - Int J Environ Res Public Health. 2021 Dec 7;18(24):12868. doi: 10.3390/ijerph182412868.