PMID- 34951211
OWN - NLM
STAT- MEDLINE
DCOM- 20211227
LR  - 20220531
IS  - 1001-5302 (Print)
IS  - 1001-5302 (Linking)
VI  - 46
IP  - 21
DP  - 2021 Nov
TI  - [Health risk assessment of exogenous harmful pollutants in Chinese medicine: a 
      review].
PG  - 5593-5599
LID - 10.19540/j.cnki.cjcmm.20210528.605 [doi]
AB  - In recent years, the quality and safety problems have been limiting the 
      internationalization of Chinese medicine. The pollutants in Chinese medicine, 
      particularly the exogenous harmful pollutants mainly including mycotoxins, 
      pesticide residues, heavy metals, harmful elements, and sulfur dioxide, are of 
      high risks for people. Therefore, the World Health Organization(WHO) and relevant 
      national organizations have clearly defined the maximum residue limits(MRLs) of 
      such pollutants. Chinese Pharmacopoeia(2020 edition, volume Ⅳ) also demonstrates 
      the detection methods, MRLs and preliminary risk assessment methods for four 
      typical exogenous harmful pollutants in Chinese medicine. Therefore, continuous 
      optimization of the health risk assessment system can further help further raise 
      the quality and safety of Chinese medicine. This paper reviews the research on 
      the health risk assessment of four typical exogenous harmful pollutants in 
      Chinese medicine and discusses the problems of and challenges for the assessment 
      system, which is expected to lay a scientific basis for the establishment of the 
      risk warning mode and response measures suitable for specific types of Chinese 
      medicine.
FAU - Sui, Ming
AU  - Sui M
AD  - Key Laboratory of Bioactive Substances and Resources Utilization of Chinese 
      Herbal Medicine, Ministry of Education,Institute of Medicinal Plant Development, 
      Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 
      100193, China School of Pharmacy, Changzhou University Changzhou 213164, China.
FAU - Kong, Dan-Dan
AU  - Kong DD
AD  - Key Laboratory of Bioactive Substances and Resources Utilization of Chinese 
      Herbal Medicine, Ministry of Education,Institute of Medicinal Plant Development, 
      Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 
      100193, China.
FAU - Ding, Shu-Min
AU  - Ding SM
AD  - School of Pharmacy, Changzhou University Changzhou 213164, China.
FAU - Yang, Mei-Hua
AU  - Yang MH
AD  - Key Laboratory of Bioactive Substances and Resources Utilization of Chinese 
      Herbal Medicine, Ministry of Education,Institute of Medicinal Plant Development, 
      Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 
      100193, China.
LA  - chi
PT  - Journal Article
PT  - Review
PL  - China
TA  - Zhongguo Zhong Yao Za Zhi
JT  - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese 
      materia medica
JID - 8913656
RN  - 0 (Drugs, Chinese Herbal)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - *Drug Contamination
MH  - *Drugs, Chinese Herbal/adverse effects/analysis
MH  - *Environmental Pollutants/adverse effects/analysis
MH  - Humans
MH  - Medicine, Chinese Traditional
MH  - *Pesticide Residues/adverse effects/analysis
MH  - Risk Assessment
OTO - NOTNLM
OT  - Chinese medicine
OT  - exogenous harmful pollutants
OT  - health risk assessment
OT  - research progress
EDAT- 2021/12/25 06:00
MHDA- 2021/12/28 06:00
CRDT- 2021/12/24 06:13
PHST- 2021/12/24 06:13 [entrez]
PHST- 2021/12/25 06:00 [pubmed]
PHST- 2021/12/28 06:00 [medline]
AID - 10.19540/j.cnki.cjcmm.20210528.605 [doi]
PST - ppublish
SO  - Zhongguo Zhong Yao Za Zhi. 2021 Nov;46(21):5593-5599. doi: 
      10.19540/j.cnki.cjcmm.20210528.605.