PMID- 34954978 OWN - NLM STAT- MEDLINE DCOM- 20211228 LR - 20211228 IS - 0254-6450 (Print) IS - 0254-6450 (Linking) VI - 42 IP - 12 DP - 2021 Dec 10 TI - [Development and evaluation of a machine learning prediction model for large for gestational age]. PG - 2143-2148 LID - 10.3760/cma.j.cn112338-20210824-00677 [doi] AB - Objective: To develop and validate a useful predictive model for large gestational age (LGA) in pregnancy using a machine learning (ML) algorithm and compare its performance with the traditional logistic regression model. Methods: Data were obtained from the National Free Preconception Health Examination Project in China, carried out in 220 counties of 31 provinces from 2010 to 2012, covering all rural couples with a planned pregnancy. This study included all teams of childbearing age who delivered newborns within 24-42 weeks of gestational age and their newborns. Ten different ML algorithms were used to establish LGA prediction models, and the prediction performance of these models was evaluated. Results: A total of 104 936 newborns were included, including 54 856 boys (52.3%) and 50 080 girls (47.7%). The incidence of LGA was 11.7% (12 279). The imbalance between the two groups was addressed by the under- sampling technique, after which the overall performance of the ML models was significantly improved. The CatBoost model achieved the highest area under the receiver-operating-characteristic curve (AUC) value of 0.932. The logistic regression model had the worst performance, with an AUC of 0.555. Conclusions: In predicting the risk for LGA in pregnancy, the ML algorithms outperform the traditional logistic regression method. Compared to other ML algorithms, CatBoost could improve the performance, and it deserves further investigation. FAU - Bai, X AU - Bai X AD - Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission/State Key Laboratory of Complex Severe and Rare Diseases/Peking Union Medical College Hospital/Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China. FAU - Luo, Y Y AU - Luo YY AD - Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission/State Key Laboratory of Complex Severe and Rare Diseases/Peking Union Medical College Hospital/Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China. FAU - Zhou, Z B AU - Zhou ZB AD - Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission/State Key Laboratory of Complex Severe and Rare Diseases/Peking Union Medical College Hospital/Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China. FAU - Su, M L AU - Su ML AD - DHC Mediway Technology Co., Ltd, Beijing 100190, China. FAU - Yang, L Q AU - Yang LQ AD - DHC Mediway Technology Co., Ltd, Beijing 100190, China. FAU - Chen, S AU - Chen S AD - Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission/State Key Laboratory of Complex Severe and Rare Diseases/Peking Union Medical College Hospital/Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China. FAU - Yang, H B AU - Yang HB AD - Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission/State Key Laboratory of Complex Severe and Rare Diseases/Peking Union Medical College Hospital/Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China. FAU - Zhu, H J AU - Zhu HJ AD - Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission/State Key Laboratory of Complex Severe and Rare Diseases/Peking Union Medical College Hospital/Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China. FAU - Pan, H AU - Pan H AD - Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission/State Key Laboratory of Complex Severe and Rare Diseases/Peking Union Medical College Hospital/Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China. LA - chi PT - Journal Article PL - China TA - Zhonghua Liu Xing Bing Xue Za Zhi JT - Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi JID - 8208604 SB - IM MH - *Algorithms MH - Female MH - Gestational Age MH - Humans MH - Infant MH - Infant, Newborn MH - Logistic Models MH - *Machine Learning MH - Male MH - Pregnancy MH - ROC Curve EDAT- 2021/12/27 06:00 MHDA- 2021/12/29 06:00 CRDT- 2021/12/26 21:44 PHST- 2021/12/26 21:44 [entrez] PHST- 2021/12/27 06:00 [pubmed] PHST- 2021/12/29 06:00 [medline] AID - 10.3760/cma.j.cn112338-20210824-00677 [doi] PST - ppublish SO - Zhonghua Liu Xing Bing Xue Za Zhi. 2021 Dec 10;42(12):2143-2148. doi: 10.3760/cma.j.cn112338-20210824-00677.