PMID- 34956499
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211228
IS  - 1943-8141 (Print)
IS  - 1943-8141 (Electronic)
IS  - 1943-8141 (Linking)
VI  - 13
IP  - 11
DP  - 2021
TI  - Clinical efficacy of thoracoscopic surgery by subxiphoid approach for thymoma and 
      its influence on intraoperative blood loss and postoperative complications.
PG  - 12843-12851
AB  - OBJECTIVE: To evaluate the clinical efficacy of thoracoscopic surgery by 
      subxiphoid approach for patients with thymoma and its influence on intraoperative 
      blood loss and postoperative complications. METHODS: From January 2019 to January 
      2020, 90 patients who underwent thoracoscopic surgery were enrolled and evenly 
      divided into a control group receiving surgery by lateral thoracic approach and 
      an experimental group adopting the subxiphoid approach according to different 
      surgical approaches, and their clinical data were retrospectively analyzed. The 
      clinical efficacy, perioperative indexes, postoperative complications, pulmonary 
      function, and inflammatory factors were compared between the two groups. Generic 
      Quality of Life Inventory-74 (GQOLI-74) was used to assess the quality of life of 
      the patients before and after surgery, and Mini-Mental State Examination (MMSE) 
      was used to assess their mental state. The Numerical Rating Scale (NRS) was used 
      to evaluate the postoperative pain of the two groups. RESULTS: After treatment, 
      the total clinical effectiveness rate of the experimental group was significantly 
      higher than that of the control group (P<0.05). The experimental group obtained 
      superior results in perioperative index and fewer postoperative complications 
      compared with the control group (P<0.05). Better performance of FEV1 and FVC was 
      observed in the experimental group than the control group (P<0.05). The 
      experimental group had significantly higher postoperative GQOLI-74 scores 
      (P<0.001) and MMSE scores (P<0.05) than the control group. Lower levels of 
      C-reactive protein (CRP), and tumor necrosis factor-alpha (TNF-alpha), and lower NRS 
      scores at 12 h and 24 h after surgery were witnessed in the experimental group 
      compared to the control group (P<0.05). CONCLUSION: For patients with thymoma, 
      the thoracoscopic surgery by subxiphoid approach is safe and effective, and can 
      reduce the intraoperative blood loss and postoperative complications.
CI  - AJTR Copyright (c) 2021.
FAU - Shen, Peng
AU  - Shen P
AD  - Department of Chest Surgery, Dongping Hospital Affiliated to Shandong First 
      Medical University Dongping 271500, Shandong, China.
FAU - Chen, Quan
AU  - Chen Q
AD  - Department of Oncology, Dongping Hospital Affiliated to Shandong First Medical 
      University Dongping 271500, Shandong, China.
FAU - Zhu, Fengwei
AU  - Zhu F
AD  - Department of General Surgery, Dongping Hospital Affiliated to Shandong First 
      Medical University Dongping 271500, Shandong, China.
FAU - Tang, Shouqi
AU  - Tang S
AD  - Department of General Surgery, Dongping Hospital Affiliated to Shandong First 
      Medical University Dongping 271500, Shandong, China.
FAU - Zhang, Xuxian
AU  - Zhang X
AD  - Department of Chest Surgery, Dongping Hospital Affiliated to Shandong First 
      Medical University Dongping 271500, Shandong, China.
FAU - Li, Feng
AU  - Li F
AD  - Department of Oncology, Dongping Hospital Affiliated to Shandong First Medical 
      University Dongping 271500, Shandong, China.
LA  - eng
PT  - Journal Article
DEP - 20211115
PL  - United States
TA  - Am J Transl Res
JT  - American journal of translational research
JID - 101493030
PMC - PMC8661206
OTO - NOTNLM
OT  - Subxiphoid approach
OT  - clinical efficacy
OT  - postoperative complications
OT  - thymoma
COIS- None.
EDAT- 2021/12/28 06:00
MHDA- 2021/12/28 06:01
PMCR- 2021/11/15
CRDT- 2021/12/27 06:27
PHST- 2021/07/22 00:00 [received]
PHST- 2021/09/27 00:00 [accepted]
PHST- 2021/12/27 06:27 [entrez]
PHST- 2021/12/28 06:00 [pubmed]
PHST- 2021/12/28 06:01 [medline]
PHST- 2021/11/15 00:00 [pmc-release]
PST - epublish
SO  - Am J Transl Res. 2021 Nov 15;13(11):12843-12851. eCollection 2021.