PMID- 34970589
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220101
IS  - 2296-875X (Print)
IS  - 2296-875X (Electronic)
IS  - 2296-875X (Linking)
VI  - 8
DP  - 2021
TI  - A Novel Titanium Cranioplasty Technique of Marking the Coronal and 
      Squamosoparietal Sutures in Three-Dimensional Titanium Mesh as Anatomical 
      Positioning Markers to Increase the Surgical Accuracy and Reduce Postoperative 
      Complications.
PG  - 754466
LID - 10.3389/fsurg.2021.754466 [doi]
LID - 754466
AB  - Objective: The objective of this research is to modify the titanium cranioplasty 
      (Ti-CP) technique to increase the surgical accuracy and preliminarily verify the 
      effectiveness and safety of this improvement. Methods: We developed a novel 
      technique of marking the coronal and squamosoparietal sutures in 
      three-dimensional (3D) titanium mesh as anatomical positioning markers and 
      designed a prospective trial in patients with a unilateral frontotemporoparietal 
      skull defect. Patients were randomly divided into two groups by the presence or 
      absence of the anatomical positioning markers, and the therapeutic effects of 
      these two groups were compared. Results: Forty-four patients were included in 
      this study, including 28 (64%) males and 16 (36%) females. The mean age was 44.8 
      +/- 15.2 years (range, 13-75 years). Overall postoperative complication rate of the 
      intervention group (18%) was significantly (P = 0.03) lower than the control 
      group (50%). Surgical accuracy of the intervention group (97.8%) was 
      significantly (P < 0.001) higher than the control group (94%). Visual analog 
      scale for cosmesis (VASC) of the intervention group (8.4) was significantly (P < 
      0.001) higher than the control group (7). The overall postoperative complication 
      rate was 34%. Multivariate analyses showed that surgical accuracy <95.8% (OR = 
      19.20, 95% CI = 3.17-116.45, P = 0.001) was significantly associated with overall 
      postoperative complications. Independent predictor of overall postoperative 
      complications was surgical accuracy (OR = 0.57, 95% CI = 0.40-0.82, P = 0.002). 
      Conclusions: This novel technique for repairing frontotemporoparietal skull 
      defects increases surgical accuracy, improves cosmetic prognosis, and reduces 
      postoperative complications. Therefore, it is a safe and effective improvement 
      for Ti-CP.
CI  - Copyright (c) 2021 Xie, Wang, Zheng, Lin, Kang and Fang.
FAU - Xie, Bing-Sen
AU  - Xie BS
AD  - Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical 
      University, Fuzhou, China.
FAU - Wang, Fang-Yu
AU  - Wang FY
AD  - Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical 
      University, Fuzhou, China.
FAU - Zheng, Shu-Fa
AU  - Zheng SF
AD  - Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical 
      University, Fuzhou, China.
FAU - Lin, Yuan-Xiang
AU  - Lin YX
AD  - Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical 
      University, Fuzhou, China.
FAU - Kang, De-Zhi
AU  - Kang DZ
AD  - Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical 
      University, Fuzhou, China.
FAU - Fang, Wen-Hua
AU  - Fang WH
AD  - Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical 
      University, Fuzhou, China.
LA  - eng
PT  - Journal Article
DEP - 20211214
PL  - Switzerland
TA  - Front Surg
JT  - Frontiers in surgery
JID - 101645127
PMC - PMC8712424
OTO - NOTNLM
OT  - accuracy
OT  - cranioplasty
OT  - outcome
OT  - surgery
OT  - three-dimensional
OT  - titanium
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/01/01 06:00
MHDA- 2022/01/01 06:01
PMCR- 2021/12/14
CRDT- 2021/12/31 06:07
PHST- 2021/08/13 00:00 [received]
PHST- 2021/10/27 00:00 [accepted]
PHST- 2021/12/31 06:07 [entrez]
PHST- 2022/01/01 06:00 [pubmed]
PHST- 2022/01/01 06:01 [medline]
PHST- 2021/12/14 00:00 [pmc-release]
AID - 10.3389/fsurg.2021.754466 [doi]
PST - epublish
SO  - Front Surg. 2021 Dec 14;8:754466. doi: 10.3389/fsurg.2021.754466. eCollection 
      2021.