PMID- 34971815
OWN - NLM
STAT- MEDLINE
DCOM- 20220113
LR  - 20230302
IS  - 1743-9159 (Electronic)
IS  - 1743-9191 (Print)
IS  - 1743-9159 (Linking)
VI  - 97
DP  - 2022 Jan
TI  - Recurrent appendicitis following successful drainage of appendicular abscess in 
      adult without interval appendectomy during COVID-19. Prospective cohort study.
PG  - 106200
LID - 10.1016/j.ijsu.2021.106200 [doi]
AB  - BACKGROUND: COVID-19 infection is a global pandemic that affected routine health 
      services and made patients fear to consult for medical health problems, even 
      acute abdominal pain. Subsequently, the incidence of complicated appendicitis 
      increased during the Covid-19 pandemic. This study aimed to evaluate recurrent 
      appendicitis after successful drainage of appendicular abscess during COVID-19. 
      MATERIAL AND METHODS: A prospective cohort study conducted in the surgical 
      emergency units of our Universities' Hospitals between March 15, 2020 to August 
      15, 2020 including patients who were admitted with the diagnosis of an 
      appendicular abscess and who underwent open or radiological drainage. Main 
      outcomes included incidence, severity, and risk factors of recurrent appendicitis 
      in patients without interval appendectomy. RESULTS: A total of 316 patients were 
      included for analysis. The mean age of the patients was 37 years (SD +/- 13). About 
      two-thirds of patients were males (60.1%). More than one-third (39.6%) had 
      co-morbidities; type 2 diabetes mellitus (T2DM) (22.5%) and hypertension (17.1%) 
      were the most frequent. Approximately one quarter (25.6%) had confirmed COVID 19 
      infection. About one-third of the patients (30.4%) had recurrent appendicitis. 
      More than half of them (56.3%) showed recurrence after three months, and 43.8% of 
      patients showed recurrence in the first three months. The most frequent grade was 
      grade I (63.5%). Most patients (77.1%) underwent open surgery. Age, T2DM, 
      hypertension, COVID-19 infection and abscess size >3 cm were significantly 
      risking predictors for recurrent appendicitis. CONCLUSIONS: Interval appendectomy 
      is suggested to prevent 56.3% of recurrent appendicitis that occurs after 3 
      months. We recommend performing interval appendectomy in older age, people with 
      diabetes, COVID-19 infected, and abscesses more than 3 cm in diameter. RESEARCH 
      QUESTION: Is interval appendectomy preventing a high incidence of recurrent 
      appendicitis after successful drainage of appendicular abscess during COVID-19 
      pandemic?
CI  - Copyright (c) 2021 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights 
      reserved.
FAU - Habeeb, Tamer A A M
AU  - Habeeb TAAM
AD  - Department of General Surgery, Faculty of Medicine, Zagazig University, Egypt 
      Doncaster and Bassetlaw Teaching Hospitals, NHS Foundation Trust, Sheffield 
      University, UK Department of Surgery, Hospital Aleman of Buenos Aires, Argentina 
      Department of Surgery, Minimally Invasive Surgery Research Center, Division of 
      Minimally Invasive and Bariatric Surgery, Rasool-e Akram Hospital, Iran 
      University of Medical Sciences, Tehran, Iran Department of Biomedical Sciences 
      for Health Milan, Italy Surgery Department General Hospital Aleksinac, Serbia.
FAU - Hussain, Abdulzahra
AU  - Hussain A
FAU - Schlottmann, Francisco
AU  - Schlottmann F
FAU - Kermansaravi, Mohammad
AU  - Kermansaravi M
FAU - Aiolfi, Alberto
AU  - Aiolfi A
FAU - Matic, Ivan
AU  - Matic I
FAU - Abdelazez, Osama
AU  - Abdelazez O
FAU - Negm, Said Mohamed
AU  - Negm SM
FAU - Baghdadi, Muhammad Ali
AU  - Baghdadi MA
FAU - Yassin, Mahmoud Abdou
AU  - Yassin MA
FAU - Sallam, Ahmed M
AU  - Sallam AM
FAU - Mohammad, Hatem
AU  - Mohammad H
FAU - Habib, Fady Mehaney
AU  - Habib FM
FAU - Abdelhamid, Mohamed I
AU  - Abdelhamid MI
FAU - Amin, Mohamed Farouk
AU  - Amin MF
LA  - eng
PT  - Journal Article
DEP - 20211229
PL  - United States
TA  - Int J Surg
JT  - International journal of surgery (London, England)
JID - 101228232
SB  - IM
CIN - Int J Surg. 2022 Mar;99:106580. PMID: 35219841
MH  - *Abdominal Abscess/epidemiology/etiology/surgery
MH  - Abscess/diagnostic imaging/epidemiology/etiology
MH  - Adult
MH  - Aged
MH  - Appendectomy/adverse effects
MH  - *Appendicitis/diagnostic imaging/surgery
MH  - *COVID-19
MH  - Child, Preschool
MH  - *Diabetes Mellitus, Type 2
MH  - Drainage
MH  - Humans
MH  - Male
MH  - Pandemics
MH  - Prospective Studies
MH  - Retrospective Studies
MH  - SARS-CoV-2
PMC - PMC8714245
OTO - NOTNLM
OT  - Appendicular abscess
OT  - COVID-19
OT  - Drainage
OT  - Interval appendectomy
OT  - Recurrent appendicitis
COIS- No conflicts of interest.
EDAT- 2022/01/01 06:00
MHDA- 2022/01/14 06:00
PMCR- 2021/12/29
CRDT- 2021/12/31 20:12
PHST- 2021/09/22 00:00 [received]
PHST- 2021/11/03 00:00 [revised]
PHST- 2021/12/24 00:00 [accepted]
PHST- 2022/01/01 06:00 [pubmed]
PHST- 2022/01/14 06:00 [medline]
PHST- 2021/12/31 20:12 [entrez]
PHST- 2021/12/29 00:00 [pmc-release]
AID - 01279778-202201000-00012 [pii]
AID - 106200 [pii]
AID - 10.1016/j.ijsu.2021.106200 [doi]
PST - ppublish
SO  - Int J Surg. 2022 Jan;97:106200. doi: 10.1016/j.ijsu.2021.106200. Epub 2021 Dec 
      29.