PMID- 34975040
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220429
IS  - 2303-9027 (Print)
IS  - 2226-7190 (Electronic)
IS  - 2226-7190 (Linking)
VI  - 10
IP  - 6
DP  - 2021 Nov-Dec
TI  - Efficacy of the Franseen needle for diagnosing gastrointestinal submucosal 
      lesions including small tumors.
PG  - 424-430
LID - 10.4103/EUS-D-21-00035 [doi]
AB  - BACKGROUND AND OBJECTIVES: Several studies have demonstrated that EUS-guided 
      fine-needle biopsy (EUS-FNB) is useful for diagnosing gastrointestinal 
      subepithelial lesions (GI SELs). However, there is limited evidence regarding the 
      use of Franseen needles during EUS-FNB for patients with GI SELs. In addition, 
      the optimal approach for diagnosing small SELs is unclear. This study aimed to 
      evaluate whether EUS-FNB using a Franseen needle was effective for diagnosing GI 
      SELs, including small lesions. METHODS: Between January 2013 and January 2020, 
      150 consecutive patients with GI SELs underwent EUS-FNA/FNB to achieve a 
      histological diagnosis. Eighty-six consecutive patients who underwent EUS-FNB 
      using a Franseen needle were compared to 64 patients who underwent EUS-FNA using 
      a conventional needle. RESULTS: The diagnostic yield was significantly higher 
      using a Franseen needle than using a conventional needle (85% vs. 75%, P = 
      0.006). Furthermore, in cases with SELs that were <20 mm, the diagnostic yield 
      was significantly higher using a Franseen needle than using a conventional needle 
      (81% vs. 45%; P = 0.003). Multivariate analysis revealed that obtaining a 
      sufficient diagnostic sample was independently predicted by Franseen needle use 
      (adjusted odds ratio: 2.8, 95% confidence interval: 1.2-6.3; P = 0.01) and tumor 
      size of >20 mm (adjusted odds ratio: 3.4, 95% confidence interval: 1.4-8.2; P = 
      0.006). CONCLUSION: Even when attempting to diagnose small GI SELs, EUS-FNB using 
      a Franseen needle appears to provide a more efficient acquisition of true 
      histological core tissue than using a conventional needle.
FAU - Nagai, Kazumasa
AU  - Nagai K
AD  - Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, 
      Japan.
FAU - Sofuni, Atsushi
AU  - Sofuni A
AD  - Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, 
      Japan.
FAU - Tsuchiya, Takayoshi
AU  - Tsuchiya T
AD  - Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, 
      Japan.
FAU - Kono, Shin
AU  - Kono S
AD  - Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, 
      Japan.
FAU - Ishii, Kentaro
AU  - Ishii K
AD  - Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, 
      Japan.
FAU - Tanaka, Reina
AU  - Tanaka R
AD  - Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, 
      Japan.
FAU - Tonozuka, Ryosuke
AU  - Tonozuka R
AD  - Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, 
      Japan.
FAU - Mukai, Shuntaro
AU  - Mukai S
AD  - Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, 
      Japan.
FAU - Yamamoto, Kenjiro
AU  - Yamamoto K
AD  - Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, 
      Japan.
FAU - Matsunami, Yukitoshi
AU  - Matsunami Y
AD  - Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, 
      Japan.
FAU - Asai, Yasutsugu
AU  - Asai Y
AD  - Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, 
      Japan.
FAU - Kurosawa, Takashi
AU  - Kurosawa T
AD  - Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, 
      Japan.
FAU - Kojima, Hiroyuki
AU  - Kojima H
AD  - Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, 
      Japan.
FAU - Yamaguchi, Hiroshi
AU  - Yamaguchi H
AD  - Department of Anatomic Pathology, Tokyo Medical University, Tokyo, Japan.
FAU - Nagao, Toshitaka
AU  - Nagao T
AD  - Department of Anatomic Pathology, Tokyo Medical University, Tokyo, Japan.
FAU - Itoi, Takao
AU  - Itoi T
AD  - Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, 
      Japan.
LA  - eng
PT  - Journal Article
PL  - China
TA  - Endosc Ultrasound
JT  - Endoscopic ultrasound
JID - 101622292
PMC - PMC8785670
OTO - NOTNLM
OT  - EUS-FNA
OT  - EUS-FNB
OT  - GIST
OT  - gastrointestinal subepithelial lesions
OT  - gastrointestinal submucosal tumor
COIS- None
EDAT- 2022/01/04 06:00
MHDA- 2022/01/04 06:01
PMCR- 2021/12/27
CRDT- 2022/01/03 05:30
PHST- 2022/01/03 05:30 [entrez]
PHST- 2022/01/04 06:00 [pubmed]
PHST- 2022/01/04 06:01 [medline]
PHST- 2021/12/27 00:00 [pmc-release]
AID - EndoscUltrasound_2021_10_6_424_333804 [pii]
AID - EUS-10-424 [pii]
AID - 10.4103/EUS-D-21-00035 [doi]
PST - ppublish
SO  - Endosc Ultrasound. 2021 Nov-Dec;10(6):424-430. doi: 10.4103/EUS-D-21-00035.