PMID- 34976508
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220104
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 13
IP  - 11
DP  - 2021 Nov
TI  - The Correlation Between Blood Group Type and Diabetes Mellitus Type II: A 
      Case-Control Observational Study From Pakistan.
PG  - e19898
LID - 10.7759/cureus.19898 [doi]
LID - e19898
AB  - Introduction Adult-onset type 2 diabetes mellitus (T2DM) is defined as a chronic 
      hyperglycemic state, characterized by insulin resistance and declining islet 
      B-cell function, eventually leading to islet B-cell function failure. The present 
      study evaluated the association of T2DM with the type of blood group.  
      Methodology A case-control study was conducted from April 2020 to September 2021 
      in Karachi, Pakistan. An electronic questionnaire was used to determine if there 
      is an association between ABO blood groups and type 2 diabetes mellitus. Our 
      study involved two groups with an equal number of participants. The patient group 
      contained participants who had been diagnosed with type 2 diabetes mellitus, 
      whereas the control group contained participants who had never been diagnosed 
      with type 2 diabetes mellitus. Information was collected through a 
      self-administered electronic questionnaire which was circulated through social 
      media. Results The mean +/- SD age was reported to be 25.98 +/- 12 years. The study 
      found a significant association between blood group B and type 2 diabetes 
      mellitus (p=0.006), whereas a negative association was seen between the blood 
      group O and type 2 diabetes mellitus (p=0.001). It should be noted, however, no 
      significant association was found between the blood groups A and AB and type 2 
      diabetes mellitus (p>0.05). Conclusion The results of this study indicate that 
      there is an association between type 2 diabetes mellitus and the ABO blood group 
      system; a significant association was found between blood group B and risk of 
      type 2 diabetes mellitus (T2DM). Nevertheless, we recommend regular screening for 
      T2DM in individuals with a high-risk profile. Those at risk can adopt measures 
      that are beneficial for them in the long run such as dietary control and physical 
      exercise. Further studies using explorative techniques with a diversified 
      population are recommended.
CI  - Copyright (c) 2021, Sharjeel et al.
FAU - Sharjeel, Simrah
AU  - Sharjeel S
AD  - Department of Medicine, Jinnah Sindh Medical University, Karachi, PAK.
FAU - Wasi, Muhammad
AU  - Wasi M
AD  - Department of Medicine, Jinnah Sindh Medical University, Karachi, PAK.
FAU - Jafri, Aliya
AU  - Jafri A
AD  - Department of Biochemistry, Jinnah Sindh Medical University, Karachi, PAK.
FAU - Raza, Fatima A
AU  - Raza FA
AD  - Department of Medicine, Karachi Medical and Dental College, Karachi, PAK.
FAU - Tariq, Zara
AU  - Tariq Z
AD  - Department of Medicine, Karachi Medical and Dental College, Karachi, PAK.
FAU - Shamim, Khizer
AU  - Shamim K
AD  - Department of Medicine, Ziauddin University, Karachi, PAK.
FAU - Abbas, Kiran
AU  - Abbas K
AD  - Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi, PAK.
FAU - Ahmed, Moiz
AU  - Ahmed M
AD  - Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi, PAK.
AD  - Department of Medicine and Surgery, Sindh Medical College, Karachi, PAK.
LA  - eng
PT  - Journal Article
DEP - 20211125
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC8712191
OTO - NOTNLM
OT  - abo blood group
OT  - adult-onset type 2 diabetes mellitus
OT  - blood
OT  - diabetes mellitus
OT  - endocrinology
COIS- The authors have declared that no competing interests exist.
EDAT- 2022/01/04 06:00
MHDA- 2022/01/04 06:01
PMCR- 2021/11/25
CRDT- 2022/01/03 05:44
PHST- 2021/11/25 00:00 [accepted]
PHST- 2022/01/03 05:44 [entrez]
PHST- 2022/01/04 06:00 [pubmed]
PHST- 2022/01/04 06:01 [medline]
PHST- 2021/11/25 00:00 [pmc-release]
AID - 10.7759/cureus.19898 [doi]
PST - epublish
SO  - Cureus. 2021 Nov 25;13(11):e19898. doi: 10.7759/cureus.19898. eCollection 2021 
      Nov.