PMID- 34985236
OWN - NLM
STAT- MEDLINE
DCOM- 20220621
LR  - 20230308
IS  - 1973-9095 (Electronic)
IS  - 1973-9087 (Print)
IS  - 1973-9087 (Linking)
VI  - 58
IP  - 3
DP  - 2022 Jun
TI  - End-range Maitland mobilization decreasing pain sensitivity in knee 
      osteoarthritis: randomized, controlled clinical trial.
PG  - 442-451
LID - 10.23736/S1973-9087.22.06680-1 [doi]
AB  - BACKGROUND: Pressure pain threshold (PPT) is a widely applied method for 
      measuring the magnitude of increased peripheral and central pain sensitivity 
      causing hyperalgesia in knee osteoarthritis (OA). Although manual therapy 
      techniques effects positively PPT, the effect of end-range Maitland mobilization 
      has not been evaluated in knee OA. AIM: The aim of this study was to investigate 
      the effect of end-range Maitland mobilization compared to sham manual therapy 
      technique on PPT and function-related measures. DESIGN: The design of the study 
      was of a randomized, controlled clinical trial. SETTING: Outpatient setting. 
      POPULATION: Forty women with moderate-to-severe knee OA. METHODS: Twenty patients 
      (N.=20) were randomly assigned to Maitland group (MG) and twenty patients (N.=20) 
      to control group (CG). Patients in MG received single end-range Maitland 
      mobilization while patients in CG received sham manual therapy technique. 
      Assessment was performed at baseline, 30 minutes and after 1-week period. Outcome 
      measures were PPT locally at knee and distant at ipsilateral extensor carpi 
      radialis longus muscle, general pain during the previous week using the Visual 
      Analogue Scale (VAS), Timed Up and Go Test (TUG) time associated with pain 
      measured with Numerating Pain Rating Scale (NPRS) and strength of passive 
      resistance of knee at onset of pain. RESULTS: Despite all outcome measures 
      improved significantly postintervention, no changes were detected after 1-week 
      period compared to postintervention in MG. No change of outcome measures was 
      found also postintervention and after 1-week period compared to postintervention 
      in CG. All postintervention results showed significant improvement in 
      between-group comparison in favor of MG. However, after 1-week period, only 
      strength of passive resistance revealed significant difference in between-group 
      comparison in favor of MG (P<0.001). CONCLUSIONS: Although end-range Maitland 
      mobilization has an immediate effect on decreasing peripheral and central pain 
      sensitivity and improving function-related measures in knee OA, these changes may 
      not cause clinically relevant effect based on data measured after 1-week period. 
      CLINICAL REHABILITATION IMPACT: Investigating the time-course of end-range 
      Maitland mobilization for determining the optimal treatment frequency during 
      rehabilitation is suggested in knee OA.
FAU - Pozsgai, Miklos
AU  - Pozsgai M
AD  - Department of Balneology, Harkany Termal Rehabilitation Center, Harkany, Hungary 
      - miklos.pozsgay@gmail.com.
AD  - Medical School, University of Pecs, Pecs, Hungary - miklos.pozsgay@gmail.com.
FAU - Peter, Ivan A
AU  - Peter IA
AD  - Department of Balneology, Harkany Termal Rehabilitation Center, Harkany, Hungary.
FAU - Farkas, Nelli
AU  - Farkas N
AD  - Medical School, Institute of Bioanalysis, University of Pecs, Pecs, Hungary.
FAU - Than, Peter
AU  - Than P
AD  - Medical School, University of Pecs, Pecs, Hungary.
AD  - Medical School, Department of Orthopaedics, University of Pecs, Pecs, Hungary.
FAU - Nusser, Nora
AU  - Nusser N
AD  - Department of Balneology, Harkany Termal Rehabilitation Center, Harkany, Hungary.
AD  - Medical School, University of Pecs, Pecs, Hungary.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20220105
PL  - Italy
TA  - Eur J Phys Rehabil Med
JT  - European journal of physical and rehabilitation medicine
JID - 101465662
SB  - IM
MH  - Female
MH  - Humans
MH  - *Osteoarthritis, Knee/rehabilitation/therapy
MH  - Pain
MH  - Pain Threshold
MH  - Postural Balance
MH  - Time and Motion Studies
MH  - Treatment Outcome
PMC - PMC9980501
COIS- Conflicts of interest.-The authors certify that there is no conflict of interest 
      with any financial organization regarding the material discussed in the 
      manuscript.
EDAT- 2022/01/06 06:00
MHDA- 2022/06/22 06:00
PMCR- 2022/01/05
CRDT- 2022/01/05 11:41
PHST- 2022/01/06 06:00 [pubmed]
PHST- 2022/06/22 06:00 [medline]
PHST- 2022/01/05 11:41 [entrez]
PHST- 2022/01/05 00:00 [pmc-release]
AID - S1973-9087.22.06680-1 [pii]
AID - 6680 [pii]
AID - 10.23736/S1973-9087.22.06680-1 [doi]
PST - ppublish
SO  - Eur J Phys Rehabil Med. 2022 Jun;58(3):442-451. doi: 
      10.23736/S1973-9087.22.06680-1. Epub 2022 Jan 5.