PMID- 3498813
OWN - NLM
STAT- MEDLINE
DCOM- 19871116
LR  - 20061115
IS  - 0022-3492 (Print)
IS  - 0022-3492 (Linking)
VI  - 58
IP  - 9
DP  - 1987 Sep
TI  - Human leukocyte antigen (HLA) DR4. Positive association with rapidly progressing 
      periodontitis.
PG  - 607-10
AB  - The relationship between human leukocyte antigens (HLA) determinants and 
      periodontitis has been examined by several authors without showing any particular 
      pattern. However, no study has investigated the HLA-D determinants, which are 
      generally associated with immune disorders, and rapidly progressive periodontitis 
      (RPP). The HLA profile of 10 RPP patients was compared with that of a healthy 
      control population (n = 120). Although no significant difference was found for 
      HLA-A, HLA-B, and HLA-C, HLA-DR4 of the HLA-D group was found in 80% of patients 
      but only in 38.3% of controls. A high frequency of HLA-DR4 has been reported in 
      rheumatoid arthritis (RA) patients. This finding may be significant in light of 
      previous reports highlighting similarities between RA and periodontal disease.
FAU - Katz, J
AU  - Katz J
AD  - Department of Oral Diagnosis, Oral Medicine and Oral Radiology, Hebrew 
      University-Hadassah School of Dental Medicine, Jerusalem, Israel.
FAU - Goultschin, J
AU  - Goultschin J
FAU - Benoliel, R
AU  - Benoliel R
FAU - Brautbar, C
AU  - Brautbar C
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - J Periodontol
JT  - Journal of periodontology
JID - 8000345
RN  - 0 (HLA Antigens)
RN  - 0 (HLA-A Antigens)
RN  - 0 (HLA-B Antigens)
RN  - 0 (HLA-C Antigens)
RN  - 0 (HLA-D Antigens)
RN  - 0 (HLA-DR Antigens)
RN  - 0 (HLA-DR4 Antigen)
SB  - IM
MH  - Adult
MH  - Female
MH  - HLA Antigens/*analysis
MH  - HLA-A Antigens
MH  - HLA-B Antigens
MH  - HLA-C Antigens
MH  - HLA-D Antigens/*analysis
MH  - HLA-DR Antigens/*analysis
MH  - HLA-DR4 Antigen
MH  - Humans
MH  - Immunity, Cellular
MH  - Male
MH  - Periodontitis/*immunology
EDAT- 1987/09/01 00:00
MHDA- 1987/09/01 00:01
CRDT- 1987/09/01 00:00
PHST- 1987/09/01 00:00 [pubmed]
PHST- 1987/09/01 00:01 [medline]
PHST- 1987/09/01 00:00 [entrez]
AID - 10.1902/jop.1987.58.9.607 [doi]
PST - ppublish
SO  - J Periodontol. 1987 Sep;58(9):607-10. doi: 10.1902/jop.1987.58.9.607.