PMID- 34988344
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240405
IS  - 2470-5470 (Electronic)
IS  - 2470-5470 (Linking)
VI  - 5
DP  - 2021 Jan-Dec
TI  - Different Electrophysiological Responses to Pain-Related Visual Stimuli Between 
      Fibromyalgia and Chronic low Back Pain Women: A Pilot Case-Control Study.
PG  - 24705470211046881
LID - 10.1177/24705470211046881 [doi]
LID - 24705470211046881
AB  - BACKGROUND: Fibromyalgia is a chronic pain syndrome which occurs in the absence 
      of an organic damage, whom causes is still unclear. Aims of this pilot study were 
      to investigate the neural correlates of fibromyalgia in response to pain-related 
      visual stimuli and explore the psychological differences among fibromyalgia, 
      chronic low back pain (CLBP) and healthy conditions. METHODS: After a clinical 
      assessment, electrophysiological responses to pain-related visual stimuli were 
      recorded using a 256-Hydrocel Geodesic-Sensor-Net. Event-related potentials 
      (ERPs), standardised low-resolution electromagnetic tomography (sLORETA), and 
      psychological (Symptom Checklist-90-Revised) data were analysed for a total 
      sample of 23 women (5 healthy volunteers, 12 fibromyalgia patients, 6 CLBP 
      patients). RESULTS: The main finding was that fibromyalgia women reported a 
      different brain response to pain-related visual stimuli on the frontal montage 
      compared to women with CLBP (p = .028). Moreover, fibromyalgia women showed an 
      increased activity mainly on the hippocampus (p = .003) and the posterior 
      cingulate cortex (p </= .001) in response to algic stimuli compared to not algic 
      ones. Lastly, these women presented higher scores on the somatization (p = .002), 
      obsession-compulsion (p = .045), depression (p = .043) and positive symptom 
      distress (p = .023) dimensions compared to the healthy women. CONCLUSIONS: These 
      preliminary results suggest that although the painful symptoms are similar, the 
      central elaboration of pain could be different between women with fibromyalgia 
      and those with CLBP. Moreover, these findings provide preliminary evidences about 
      the great alert and the central sensitivity to pain-related information regarding 
      fibromyalgia patients.
CI  - (c) The Author(s) 2021.
FAU - Lai, Carlo
AU  - Lai C
AUID- ORCID: 0000-0002-7638-0375
AD  - Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza 
      University, Rome, Italy. RINGGOLD: 9311
FAU - Ciacchella, Chiara
AU  - Ciacchella C
AD  - Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza 
      University, Rome, Italy. RINGGOLD: 9311
FAU - Pellicano, Gaia Romana
AU  - Pellicano GR
AD  - Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza 
      University, Rome, Italy. RINGGOLD: 9311
FAU - Altavilla, Daniela
AU  - Altavilla D
AD  - Department of Philosophy, Communication and Performing Arts, "Roma Tre" 
      University, Rome, Italy. RINGGOLD: 19012
FAU - Sambucini, Daniela
AU  - Sambucini D
AD  - Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza 
      University, Rome, Italy. RINGGOLD: 9311
FAU - Paolucci, Teresa
AU  - Paolucci T
AD  - Department of Oral and Biotechnological Biomedical Sciences, Physical Medicine 
      and Rehabilitation, University of G. D'Annunzio of Chieti-Pescara, Chieti, Italy. 
      RINGGOLD: 9301
FAU - Sorgi, Maria Laura
AU  - Sorgi ML
AD  - Department of Clinical and Molecular Medicine, Sant' Andrea University Hospital, 
      Sapienza University of, Rome, Italy. RINGGOLD: 9311
FAU - Di Franco, Manuela
AU  - Di Franco M
AD  - Rheumatology Unit, Department of Internal Medicine and Medical Specialties, 
      Sapienza University of Rome, Italy.
FAU - Saggini, Raoul
AU  - Saggini R
AD  - Department of Oral and Biotechnological Biomedical Sciences, Physical Medicine 
      and Rehabilitation, University of G. D'Annunzio of Chieti-Pescara, Chieti, Italy. 
      RINGGOLD: 9301
FAU - Aceto, Paola
AU  - Aceto P
AD  - Department of Emergency, anesthesiological and reanimation sciences, Fondazione 
      Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. RINGGOLD: 18654
AD  - Department of Basic Biotechnological Sciences, Intensive Care and Perioperative 
      Clinics, University of Sacred Heart, Rome, Italy. RINGGOLD: 96983
LA  - eng
PT  - Journal Article
DEP - 20211202
PL  - United States
TA  - Chronic Stress (Thousand Oaks)
JT  - Chronic stress (Thousand Oaks, Calif.)
JID - 101701229
PMC - PMC8723168
OTO - NOTNLM
OT  - ERP
OT  - chronic low back pain
OT  - fibromyalgia
OT  - neural correlates
OT  - sLORETA
COIS- Declaration of Conflicting Interests: The author(s) declared no potential 
      conflicts of interest with respect to the research, authorship, and/or 
      publication of this article.
EDAT- 2022/01/07 06:00
MHDA- 2022/01/07 06:01
PMCR- 2021/12/02
CRDT- 2022/01/06 06:02
PHST- 2021/07/30 00:00 [received]
PHST- 2021/08/31 00:00 [accepted]
PHST- 2022/01/06 06:02 [entrez]
PHST- 2022/01/07 06:00 [pubmed]
PHST- 2022/01/07 06:01 [medline]
PHST- 2021/12/02 00:00 [pmc-release]
AID - 10.1177_24705470211046881 [pii]
AID - 10.1177/24705470211046881 [doi]
PST - epublish
SO  - Chronic Stress (Thousand Oaks). 2021 Dec 2;5:24705470211046881. doi: 
      10.1177/24705470211046881. eCollection 2021 Jan-Dec.