PMID- 34988725
OWN - NLM
STAT- MEDLINE
DCOM- 20220404
LR  - 20220405
IS  - 1437-7799 (Electronic)
IS  - 1342-1751 (Linking)
VI  - 26
IP  - 4
DP  - 2022 Apr
TI  - Long-term social outcome after pediatric kidney transplantation: a single-center 
      experience.
PG  - 368-375
LID - 10.1007/s10157-021-02158-w [doi]
AB  - BACKGROUND: Patient and graft survival rates after pediatric kidney 
      transplantation have improved recently. Therefore, the quality of life or social 
      outcome after kidney transplantation has become important for patients and their 
      families. METHODS: Patients who underwent kidney transplantation at < 18 years 
      old and were observed for > 10 years were included in this study. The median age 
      at first kidney transplantation was 9.2 (interquartile range [IQR] = 5.6-13.0) 
      years; there were 56 males and 50 females. The median age at last follow-up was 
      29.9 (IQR = 22.2-36.0) years. We evaluated the patients' renal function, growth, 
      professional status, and marital status at the last follow-up. RESULTS: The 
      percentage of functioning grafts at the last follow-up was 81.1%; 73 patients 
      (68.9%) had a first graft. The mean estimated GFR was 
      51.0 +/- 20.5 mL/min/1.73 m(2). Twenty patients received dialysis for graft 
      failure. The mean final heights of the males and females were 158.1 +/- 9.2 cm 
      (- 2.2 standard deviations) and 149.1 +/- 6.4 cm (- 1.7 standard deviations), 
      respectively. Excluding 23 students, 63 patients (75.9%) were employed. Office 
      worker was the most common profession. Twelve patients (14.5%) were unemployed. 
      Of patients > 20 years old, 14 (16.7%), three males and 11 females, were married. 
      Five females had one child each. CONCLUSIONS: The graft survival rate was 
      favorable. The final height was short, particularly in male. The rate of 
      employment was relatively high. The rate of marriage and having children were 
      still low. Improving the social outcome is an important problem after pediatric 
      kidney transplantation.
CI  - (c) 2021. Japanese Society of Nephrology.
FAU - Hamasaki, Yuko
AU  - Hamasaki Y
AUID- ORCID: 0000-0002-2015-9073
AD  - Department of Nephrology, Faculty of Medicine, Toho University, 6-11-1, 
      Omori-Nishi, Ota-Ku, Tokyo, 143-8541, Japan. yuhamasaki@med.toho-u.ac.jp.
FAU - Hashimoto, Junya
AU  - Hashimoto J
AD  - Department of Nephrology, Faculty of Medicine, Toho University, 6-11-1, 
      Omori-Nishi, Ota-Ku, Tokyo, 143-8541, Japan.
FAU - Aoki, Yujiro
AU  - Aoki Y
AD  - Department of Nephrology, Faculty of Medicine, Toho University, 6-11-1, 
      Omori-Nishi, Ota-Ku, Tokyo, 143-8541, Japan.
FAU - Kubota, Mai
AU  - Kubota M
AD  - Department of Nephrology, Faculty of Medicine, Toho University, 6-11-1, 
      Omori-Nishi, Ota-Ku, Tokyo, 143-8541, Japan.
FAU - Muramatsu, Masaki
AU  - Muramatsu M
AD  - Department of Nephrology, Faculty of Medicine, Toho University, 6-11-1, 
      Omori-Nishi, Ota-Ku, Tokyo, 143-8541, Japan.
FAU - Kawamura, Takeshi
AU  - Kawamura T
AD  - Department of Nephrology, Faculty of Medicine, Toho University, 6-11-1, 
      Omori-Nishi, Ota-Ku, Tokyo, 143-8541, Japan.
FAU - Shishido, Seiichiro
AU  - Shishido S
AD  - Department of Pediatric Nephrology, Faculty of Medicine, Toho University, Tokyo, 
      Japan.
FAU - Sakai, Ken
AU  - Sakai K
AD  - Department of Nephrology, Faculty of Medicine, Toho University, 6-11-1, 
      Omori-Nishi, Ota-Ku, Tokyo, 143-8541, Japan.
LA  - eng
PT  - Journal Article
DEP - 20220106
PL  - Japan
TA  - Clin Exp Nephrol
JT  - Clinical and experimental nephrology
JID - 9709923
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Graft Rejection
MH  - Graft Survival
MH  - Humans
MH  - *Kidney Transplantation/adverse effects
MH  - Male
MH  - Quality of Life
MH  - Renal Dialysis
MH  - Retrospective Studies
MH  - Survival Rate
MH  - Treatment Outcome
MH  - Young Adult
OTO - NOTNLM
OT  - Employment rate
OT  - Marriage rate
OT  - Pediatric kidney transplant
OT  - Social outcome
EDAT- 2022/01/07 06:00
MHDA- 2022/04/05 06:00
CRDT- 2022/01/06 06:12
PHST- 2020/12/30 00:00 [received]
PHST- 2021/11/05 00:00 [accepted]
PHST- 2022/01/07 06:00 [pubmed]
PHST- 2022/04/05 06:00 [medline]
PHST- 2022/01/06 06:12 [entrez]
AID - 10.1007/s10157-021-02158-w [pii]
AID - 10.1007/s10157-021-02158-w [doi]
PST - ppublish
SO  - Clin Exp Nephrol. 2022 Apr;26(4):368-375. doi: 10.1007/s10157-021-02158-w. Epub 
      2022 Jan 6.