PMID- 34993832
OWN - NLM
STAT- MEDLINE
DCOM- 20220413
LR  - 20220716
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Print)
IS  - 0944-1344 (Linking)
VI  - 29
IP  - 20
DP  - 2022 Apr
TI  - Association of urinary triclosan, methyl triclosan, triclocarban, and 
      2,4-dichlorophenol levels with anthropometric and demographic parameters in 
      children and adolescents in 2020 (case study: Kerman, Iran).
PG  - 30754-30763
LID - 10.1007/s11356-021-18466-3 [doi]
AB  - Endocrine-disrupting chemicals (EDCs) can be a major risk factor for 
      noncommunicable illnesses, especially when children are exposed to them. The 
      purpose of this study was to assess the urine concentrations of triclosan (TCS), 
      methyl triclosan (MTCS), triclocarban (TCC), and 2,4-dichlorophenol (2,4-DCP) and 
      its association with anthropometric and demographic parameters in children and 
      adolescents aged 6-18 living in Kerman, Iran, in 2020. A GC/MS instrument was 
      used to measure the concentrations of the analytes. TCS, MTCS, TCC, and 2,4-DCP 
      geometric mean concentrations (microg/L) were 4.32 +/- 2.08, 1.73 +/- 0.88, 4.66 +/- 10.25, 
      and 0.19 +/- 0.14, respectively. TCS, MTCS, TCC, and 2,4-DCP were shown to have a 
      positive and significant association with BMI z-score and BMI (p-value < 0.01). 
      TCS and MTCS have a positive, strong, and substantial association 
      (p-value < 0.01, r = 0.74). There was no significant association between the 
      waist circumference (WC) and the analytes studied. In addition, there was a close 
      association between analyte concentration and demographic parameters (smoking, 
      education, income, etc.) overall. In Kerman, Iran, the current study was the 
      first to look into the association between TCS, MTCS, TCC, and 2,4-DCP analytes 
      and anthropometric and demographic data. The levels of urinary TCS, MTCS, TCC, 
      2,4-DCP, and anthropometric parameters in children and adolescents are shown to 
      have a significant association in this study. However, because the current study 
      is cross-sectional and it is uncertain if a single experiment accurately reflects 
      long-term exposure to these analytes, more research is needed to determine the 
      impact of these analyses on the health of children and adolescents.
CI  - (c) 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, 
      part of Springer Nature.
FAU - Nasab, Habibeh
AU  - Nasab H
AD  - Environmental Health Engineering Research Center, Kerman University of Medical 
      Sciences, Kerman, Iran.
AD  - Department of Environmental Health Engineering, Faculty of Public Health, Kerman 
      University of Medical Sciences, Kerman, Iran.
FAU - Rajabi, Saeed
AU  - Rajabi S
AD  - Environmental Health Engineering Research Center, Kerman University of Medical 
      Sciences, Kerman, Iran.
AD  - Department of Environmental Health Engineering, School of Health, Shiraz 
      University of Medical Sciences, Shiraz, Iran.
FAU - Mirzaee, Moghaddameh
AU  - Mirzaee M
AD  - Modeling in Health Research Center, Institute for Futures Studies in Health, 
      Kerman University of Medical Sciences, Kerman, Iran.
FAU - Hashemi, Majid
AU  - Hashemi M
AUID- ORCID: 0000-0003-3254-2296
AD  - Environmental Health Engineering Research Center, Kerman University of Medical 
      Sciences, Kerman, Iran. mhashemi120@gmail.com.
AD  - Department of Environmental Health Engineering, Faculty of Public Health, Kerman 
      University of Medical Sciences, Kerman, Iran. mhashemi120@gmail.com.
LA  - eng
GR  - 98001219/Environmental Health Engineering Research Center, Kerman University of 
      Medical Sciences, Kerman, Iran/
PT  - Journal Article
DEP - 20220107
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Carbanilides)
RN  - 0 (Chlorophenols)
RN  - 0 (Phenols)
RN  - 4NM5039Y5X (Triclosan)
RN  - 5174UR1DP5 (methyl triclosan)
RN  - BGG1Y1ED0Y (triclocarban)
RN  - R669TG1950 (2,4-dichlorophenol)
SB  - IM
MH  - Adolescent
MH  - *Carbanilides/analysis
MH  - Child
MH  - Chlorophenols
MH  - Cross-Sectional Studies
MH  - Demography
MH  - Humans
MH  - Iran
MH  - Phenols/analysis
MH  - *Triclosan/analogs & derivatives/analysis
PMC - PMC8739350
OTO - NOTNLM
OT  - Adolescent
OT  - Body mass index
OT  - Children
OT  - Demographic factors
OT  - Endocrine-disrupting chemicals
OT  - Obesity
COIS- The authors declare no competing interests.
EDAT- 2022/01/08 06:00
MHDA- 2022/04/14 06:00
PMCR- 2022/01/07
CRDT- 2022/01/07 06:43
PHST- 2021/11/11 00:00 [received]
PHST- 2021/12/29 00:00 [accepted]
PHST- 2022/01/08 06:00 [pubmed]
PHST- 2022/04/14 06:00 [medline]
PHST- 2022/01/07 06:43 [entrez]
PHST- 2022/01/07 00:00 [pmc-release]
AID - 10.1007/s11356-021-18466-3 [pii]
AID - 18466 [pii]
AID - 10.1007/s11356-021-18466-3 [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2022 Apr;29(20):30754-30763. doi: 
      10.1007/s11356-021-18466-3. Epub 2022 Jan 7.