PMID- 34995271
OWN - NLM
STAT- MEDLINE
DCOM- 20220323
LR  - 20230322
IS  - 1524-4040 (Electronic)
IS  - 0148-396X (Linking)
VI  - 90
IP  - 2
DP  - 2022 Feb 1
TI  - Preoperative Duration of Symptoms Does Not Affect Outcomes of Anterior Lumbar 
      Interbody Fusion.
PG  - 215-220
LID - 10.1227/NEU.0000000000001782 [doi]
AB  - BACKGROUND: Previous studies have examined the impact of preoperative duration of 
      symptoms (DOS) on lumbar spinal surgery outcomes although this has not been 
      explored for anterior lumbar interbody fusion (ALIF). OBJECTIVE: To assess the 
      impact of preoperative DOS on patient-reported outcome measures (PROMs) of ALIF 
      with posterior instrumentation. METHODS: A database was retrospectively reviewed 
      for ALIFs with posterior instrumentation. PROMs recorded at preoperative, 6-wk, 
      12-wk, 6-mo, and 1-yr postoperative timepoints included Visual Analog Scale back 
      and leg, Oswestry Disability Index, 12-Item Short-Form Physical Component Score 
      (SF-12 PCS), and PROM Information System physical function. Achievement of 
      minimum clinically important difference (MCID) was determined by comparing 
      differences in postoperative PROMs from baseline to established values. Patients 
      were grouped based on preoperative DOS into <1-yr and >/=1-yr groups. Differences 
      in PROMs were compared using a t-test, whereas MCID achievement used a chi2 test. 
      RESULTS: Fifty-three patients were included, with 20 in the <1-yr group and 33 in 
      the >/=1-yr group. The most common diagnosis was isthmic spondylolisthesis. No 
      significant preoperative differences were observed in any PROM. DOS groups 
      demonstrated significantly different scores for SF-12 PCS at 6 wk (P = .049). No 
      significant differences in MCID achievement were observed between groups for any 
      PROM. CONCLUSION: ALIF patients demonstrated similar levels of pain, disability, 
      and physical function regardless of preoperative DOS, except for back pain and 
      physical function at intermittent timepoints. MCID achievement did not differ 
      based on DOS for all outcome measures.
CI  - Copyright (c) Congress of Neurological Surgeons 2021. All rights reserved.
FAU - Cha, Elliot D K
AU  - Cha EDK
AUID- ORCID: 0000-0001-8118-008
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA.
FAU - Lynch, Conor P
AU  - Lynch CP
AUID- ORCID: 0000-0002-9554-2878
FAU - Patel, Madhav R
AU  - Patel MR
FAU - Jacob, Kevin C
AU  - Jacob KC
FAU - Geoghegan, Cara E
AU  - Geoghegan CE
FAU - Jadczak, Caroline N
AU  - Jadczak CN
FAU - Mohan, Shruthi
AU  - Mohan S
FAU - Singh, Kern
AU  - Singh K
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Neurosurgery
JT  - Neurosurgery
JID - 7802914
SB  - IM
MH  - Humans
MH  - Lumbar Vertebrae/surgery
MH  - Lumbosacral Region/surgery
MH  - Retrospective Studies
MH  - *Spinal Fusion
MH  - *Spondylolisthesis/surgery
MH  - Treatment Outcome
EDAT- 2022/01/08 06:00
MHDA- 2022/03/24 06:00
CRDT- 2022/01/07 17:20
PHST- 2021/02/09 00:00 [received]
PHST- 2021/09/01 00:00 [accepted]
PHST- 2022/01/08 06:00 [pubmed]
PHST- 2022/03/24 06:00 [medline]
PHST- 2022/01/07 17:20 [entrez]
AID - 00006123-202202000-00009 [pii]
AID - 10.1227/NEU.0000000000001782 [doi]
PST - ppublish
SO  - Neurosurgery. 2022 Feb 1;90(2):215-220. doi: 10.1227/NEU.0000000000001782.