PMID- 35000341
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220122
IS  - 2586-6583 (Print)
IS  - 2586-6591 (Electronic)
IS  - 2586-6591 (Linking)
VI  - 18
IP  - 4
DP  - 2021 Dec
TI  - Outcomes of Transforaminal Lumbar Interbody Fusion Using Unilateral Versus 
      Bilateral Interbody Cages.
PG  - 854-862
LID - 10.14245/ns.2142248.124 [doi]
AB  - OBJECTIVE: To assess the impact of bilateral versus unilateral interbody cages on 
      outcomes for minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) 
      procedures. METHODS: A retrospective review for primary, elective, single-level 
      MIS TLIF procedures with bilateral posterior instrumentation from 2008-2020 was 
      performed. Patients were grouped according to unilateral or bilateral interbody 
      cage use. Procedures performed without static interbody cages or indicated for 
      trauma, infection, malignancy were excluded. Patient-reported outcomes (PROs) 
      included visual analogue scale (VAS), Oswestry Disability Index, 12-item Short 
      Form health survey physical composite score (SF-12 PCS), PatientReported Outcome 
      Measurement Information System physical function (PROMIS-PF). PROs were collected 
      preoperatively and postoperatively. Change in PROs (Delta) was calculated and 
      compared between groups. Achievement of minimum clinically important difference 
      (MCID) was calculated using established values from the literature. Achievement 
      rates were compared between groups using logistic regression. RESULTS: The study 
      included 151 patients, with 111 unilateral and 40 bilateral cage placements. 
      Charlson Comorbidity Index, diabetes, and insurance status differed between 
      groups (p < 0.050). Prevalence of degenerative and isthmic spondylolisthesis 
      (both p </= 0.002), operative level (p = 0.003), and postoperative length of stay 
      (p = 0.022) significantly differed between groups. The unilateral group had lower 
      1-year arthrodesis rates (p = 0.035). Preoperative VAS leg (p = 0.017) and SF-12 
      PCS (p = 0.045) were worse for the unilateral group. DeltaPROMIS-PF was greater for 
      the bilateral group at 2 years (p = 0.001). Majority of patients achieved an 
      overall MCID for all PROs, except VAS leg (bilateral group). CONCLUSION: While 
      preoperative status and postoperative arthrodesis rates differed, patients 
      achieved an MCID at similar rates regardless of use of unilateral or bilateral 
      cages.
FAU - Lynch, Conor P
AU  - Lynch CP
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Cha, Elliot D K
AU  - Cha EDK
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Rush Iii, Augustus J
AU  - Rush Iii AJ
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Jadczak, Caroline N
AU  - Jadczak CN
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Mohan, Shruthi
AU  - Mohan S
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Geoghegan, Cara E
AU  - Geoghegan CE
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Singh, Kern
AU  - Singh K
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
LA  - eng
PT  - Journal Article
DEP - 20211231
PL  - Korea (South)
TA  - Neurospine
JT  - Neurospine
JID - 101724936
PMC - PMC8752695
OTO - NOTNLM
OT  - Instrumentation
OT  - Interbody cage
OT  - Lumbar fusion
OT  - Patient-reported outcomes
OT  - Transforaminal lumbar interbody fusion
COIS- The authors have nothing to disclose.
EDAT- 2022/01/10 06:00
MHDA- 2022/01/10 06:01
PMCR- 2021/12/01
CRDT- 2022/01/09 23:42
PHST- 2021/03/03 00:00 [received]
PHST- 2021/03/28 00:00 [accepted]
PHST- 2022/01/09 23:42 [entrez]
PHST- 2022/01/10 06:00 [pubmed]
PHST- 2022/01/10 06:01 [medline]
PHST- 2021/12/01 00:00 [pmc-release]
AID - ns.2142248.124 [pii]
AID - ns-2142248-124 [pii]
AID - 10.14245/ns.2142248.124 [doi]
PST - ppublish
SO  - Neurospine. 2021 Dec;18(4):854-862. doi: 10.14245/ns.2142248.124. Epub 2021 Dec 
      31.