PMID- 35000584
OWN - NLM
STAT- MEDLINE
DCOM- 20220211
LR  - 20220211
IS  - 2047-2994 (Electronic)
IS  - 2047-2994 (Linking)
VI  - 11
IP  - 1
DP  - 2022 Jan 9
TI  - Droplet precautions on-site (DroPS) during the influenza season 2018/2019: a 
      possible alternative to single room isolation for respiratory viral infections.
PG  - 2
LID - 10.1186/s13756-021-01038-y [doi]
LID - 2
AB  - BACKGROUND: The guideline-driven and widely implemented single room isolation 
      strategy for respiratory viral infections (RVI) such as influenza or respiratory 
      syncytial virus (RSV) can lead to a shortage of available hospital beds. We 
      discuss our experience with the introduction of droplet precautions on-site 
      (DroPS) as a possible alternative. METHODS: During the 2018/19 influenza season 
      we introduced DroPS on several wards of a single tertiary care center, while 
      other wards maintained the traditional single room isolation strategy. On a daily 
      basis, we evaluated patients for the development of respiratory symptoms and 
      screened those with a clinical diagnosis of hospital-acquired respiratory viral 
      infection (HARVI) for influenza/RSV by molecular rapid test. If negative, it was 
      followed by a multiplex respiratory virus PCR. We report the concept of DroPS, 
      the feasibility of the strategy and the rate of microbiologically confirmed HARVI 
      with influenza or RSV infection on the DroPS wards compared to wards using the 
      traditional single room isolation strategy. RESULTS: We evaluated all 
      hospitalised patients at risk for a HARVI, 741 (72%) on the DroPS wards and 293 
      (28%) on the regular wards. The hospital-acquired infection rate with influenza 
      or RSV was 2/741 (0.3%; 1x influenza A, 1x RSV) on the DroPS wards and 2/293 
      (0.7%; 2x influenza A) on the regular wards. CONCLUSIONS: Droplet precautions 
      on-site (DroPS) may be a simple and potentially resource-saving alternative to 
      the standard single room isolation strategy for respiratory viral infections. 
      Further studies in a larger clinical context are needed to document its safety.
CI  - (c) 2021. The Author(s).
FAU - Birrer, Michele
AU  - Birrer M
AUID- ORCID: 0000-0002-7203-482X
AD  - Department of Infectious Diseases, Inselspital, Bern University Hospital, 
      University of Bern, Frohburgstrasse 3, 6002, Luzern, Switzerland. 
      michele.birrer@insel.ch.
FAU - Perrig, Martin
AU  - Perrig M
AD  - Department of General Internal Medicine, Inselspital, Bern University Hospital, 
      University of Bern, Bern, Switzerland.
FAU - Hobi, Fabienne
AU  - Hobi F
AD  - Department of Infectious Diseases, Inselspital, Bern University Hospital, 
      University of Bern, Frohburgstrasse 3, 6002, Luzern, Switzerland.
FAU - Gfeller, Christina
AU  - Gfeller C
AD  - Department of Infectious Diseases, Inselspital, Bern University Hospital, 
      University of Bern, Frohburgstrasse 3, 6002, Luzern, Switzerland.
FAU - Atkinson, Andrew
AU  - Atkinson A
AD  - Department of Infectious Diseases, Inselspital, Bern University Hospital, 
      University of Bern, Frohburgstrasse 3, 6002, Luzern, Switzerland.
FAU - Egger, Martin
AU  - Egger M
AD  - Hospital Hygiene, Regional Hospital Emmental, Burgdorf, Switzerland.
FAU - Bartholdi, Corinne
AU  - Bartholdi C
AD  - Department of General Internal Medicine, Inselspital, Bern University Hospital, 
      University of Bern, Bern, Switzerland.
FAU - Aujesky, Drahomir
AU  - Aujesky D
AD  - Department of General Internal Medicine, Inselspital, Bern University Hospital, 
      University of Bern, Bern, Switzerland.
FAU - Marschall, Jonas
AU  - Marschall J
AUID- ORCID: 0000-0002-0052-3210
AD  - Department of Infectious Diseases, Inselspital, Bern University Hospital, 
      University of Bern, Frohburgstrasse 3, 6002, Luzern, Switzerland.
AD  - Division of Infectious Diseases, Department of Medicine, Washington University 
      School of Medicine, St. Louis, MO, USA.
FAU - Sommerstein, Rami
AU  - Sommerstein R
AUID- ORCID: 0000-0003-1011-6878
AD  - Department of Infectious Diseases, Inselspital, Bern University Hospital, 
      University of Bern, Frohburgstrasse 3, 6002, Luzern, Switzerland. 
      rami.sommerstein@hirslanden.ch.
AD  - Department Health Sciences and Medicine, Clinic St. Anna, University of Lucerne, 
      Bern, Switzerland. rami.sommerstein@hirslanden.ch.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20220109
PL  - England
TA  - Antimicrob Resist Infect Control
JT  - Antimicrobial resistance and infection control
JID - 101585411
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - *Hospitals
MH  - Humans
MH  - Infection Control/*methods
MH  - Influenza, Human/*prevention & control
MH  - Male
MH  - Middle Aged
MH  - Pilot Projects
MH  - Respiratory Syncytial Virus Infections/*prevention & control
MH  - Seasons
MH  - Switzerland
PMC - PMC8743058
OTO - NOTNLM
OT  - Droplet precautions
OT  - Health-care acquired infections
OT  - Healthcare epidemiology
OT  - Hospital-acquired infection
OT  - Influenza
OT  - Isolation
OT  - Respiratory viral infection
OT  - Virus
COIS- All authors report no competing interests relevant to this article.
EDAT- 2022/01/11 06:00
MHDA- 2022/02/12 06:00
PMCR- 2022/01/09
CRDT- 2022/01/10 05:39
PHST- 2021/11/28 00:00 [received]
PHST- 2021/12/02 00:00 [accepted]
PHST- 2022/01/10 05:39 [entrez]
PHST- 2022/01/11 06:00 [pubmed]
PHST- 2022/02/12 06:00 [medline]
PHST- 2022/01/09 00:00 [pmc-release]
AID - 10.1186/s13756-021-01038-y [pii]
AID - 1038 [pii]
AID - 10.1186/s13756-021-01038-y [doi]
PST - epublish
SO  - Antimicrob Resist Infect Control. 2022 Jan 9;11(1):2. doi: 
      10.1186/s13756-021-01038-y.