PMID- 35005915
OWN - NLM
STAT- MEDLINE
DCOM- 20220119
LR  - 20221207
IS  - 2576-6422 (Electronic)
IS  - 2576-6422 (Linking)
VI  - 4
IP  - 12
DP  - 2021 Dec 20
TI  - Emerging Phospholipid Nanobiomaterials for Biomedical Applications to 
      Lab-on-a-Chip, Drug Delivery, and Cellular Engineering.
PG  - 8110-8128
LID - 10.1021/acsabm.1c00932 [doi]
AB  - The design of advanced nanobiomaterials to improve analytical accuracy and 
      therapeutic efficacy has become an important prerequisite for the development of 
      innovative nanomedicines. Recently, phospholipid nanobiomaterials including 
      2-methacryloyloxyethyl phosphorylcholine (MPC) have attracted great attention 
      with remarkable characteristics such as resistance to nonspecific protein 
      adsorption and cell adhesion for various biomedical applications. Despite many 
      recent reports, there is a lack of comprehensive review on the phospholipid 
      nanobiomaterials from synthesis to diagnostic and therapeutic applications. Here, 
      we review the synthesis and characterization of phospholipid nanobiomaterials 
      focusing on MPC polymers and highlight their attractive potentials for 
      applications in micro/nanofabricated fluidic devices, biosensors, lab-on-a-chip, 
      drug delivery systems (DDSs), COVID-19 potential usages for early diagnosis and 
      even treatment, and artificial extracellular matrix scaffolds for cellular 
      engineering.
FAU - Rahimnejad, Maedeh
AU  - Rahimnejad M
AD  - Biomedical Engineering Institute, School of Medicine, Universite de Montreal, 
      Montreal, Quebec H2X 0A9, Canada.
AD  - Department of Physics, Sharif University of Technology, P.O. Box 11155-9161, 
      Tehran , Iran.
FAU - Rabiee, Navid
AU  - Rabiee N
AUID- ORCID: 0000-0002-6945-8541
AD  - Department of Physics, Sharif University of Technology, P.O. Box 11155-9161, 
      Tehran , Iran.
FAU - Ahmadi, Sepideh
AU  - Ahmadi S
AD  - Student Research Committee, Department of Medical Biotechnology, School of 
      Advanced Technologies in Medicine, Shahid Beheshti University of Medical 
      Sciences, Tehran 19857-17443, Iran.
AD  - Cellular and Molecular Biology Research Center, Shahid Beheshti University of 
      Medical Sciences, Tehran 19857-17443, Iran.
FAU - Jahangiri, Sepideh
AU  - Jahangiri S
AD  - Department of Physics, Sharif University of Technology, P.O. Box 11155-9161, 
      Tehran , Iran.
AD  - Department of Biomedical Sciences, Faculty of Medicine, Universite de Montreal, 
      Montreal, Quebec H2X 0A9, Canada.
FAU - Sajadi, S Mohammad
AU  - Sajadi SM
AD  - Department of Nutrition, Cihan University-Erbil, Erbil 44001, Kurdistan Region, 
      Iraq.
AD  - Department of Phytochemistry, SRC, Soran University, Soran City 44008, Kurdistan 
      Region, Iraq.
FAU - Akhavan, Omid
AU  - Akhavan O
AUID- ORCID: 0000-0001-8033-5393
AD  - Department of Physics, Sharif University of Technology, P.O. Box 11155-9161, 
      Tehran , Iran.
FAU - Saeb, Mohammad Reza
AU  - Saeb MR
AUID- ORCID: 0000-0001-7860-5243
AD  - Department of Polymer Technology, Faculty of Chemistry, Gdansk University of 
      Technology, G. Narutowicza 11/12 80-233, Gdansk 80-233, Poland.
FAU - Kwon, Woosung
AU  - Kwon W
AUID- ORCID: 0000-0001-9362-7686
AD  - Department of Chemical and Biological Engineering, Sookmyung Women's University, 
      100 Cheongpa-ro 47-gil, Yongsan-gu, Seoul 04310, Korea.
FAU - Kim, Mungu
AU  - Kim M
AD  - Department of Materials Science and Engineering, Pohang University of Science and 
      Technology (POSTECH), 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, Korea.
FAU - Hahn, Sei Kwang
AU  - Hahn SK
AUID- ORCID: 0000-0002-7718-6259
AD  - Department of Materials Science and Engineering, Pohang University of Science and 
      Technology (POSTECH), 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, Korea.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20211129
PL  - United States
TA  - ACS Appl Bio Mater
JT  - ACS applied bio materials
JID - 101729147
RN  - 0 (Biocompatible Materials)
RN  - 0 (Drug Carriers)
RN  - 0 (Phospholipids)
SB  - IM
MH  - Biocompatible Materials/*chemistry
MH  - Biosensing Techniques/instrumentation/methods
MH  - COVID-19/diagnosis/virology
MH  - Drug Carriers/*chemistry
MH  - Humans
MH  - *Lab-On-A-Chip Devices
MH  - Microscopy, Confocal
MH  - Nanostructures/*chemistry
MH  - Phospholipids/*chemistry
MH  - SARS-CoV-2/isolation & purification
MH  - COVID-19 Drug Treatment
OTO - NOTNLM
OT  - cellular engineering
OT  - drug delivery
OT  - lab-on-a-chip
OT  - nanobiomaterials
OT  - phospholipid
EDAT- 2022/01/11 06:00
MHDA- 2022/01/20 06:00
CRDT- 2022/01/10 12:15
PHST- 2022/01/10 12:15 [entrez]
PHST- 2022/01/11 06:00 [pubmed]
PHST- 2022/01/20 06:00 [medline]
AID - 10.1021/acsabm.1c00932 [doi]
PST - ppublish
SO  - ACS Appl Bio Mater. 2021 Dec 20;4(12):8110-8128. doi: 10.1021/acsabm.1c00932. 
      Epub 2021 Nov 29.