PMID- 35006306
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20220302
LR  - 20231213
IS  - 1618-2650 (Electronic)
IS  - 1618-2642 (Linking)
VI  - 414
IP  - 7
DP  - 2022 Mar
TI  - Simultaneous and rapid detection of polychlorinated phenols in water samples by 
      surface-enhanced Raman spectroscopy combined with principal component analysis.
PG  - 2385-2395
LID - 10.1007/s00216-022-03876-0 [doi]
AB  - In this work, a simple, high-throughput, and sensitive analytical method based on 
      surface-enhanced Raman spectroscopy (SERS) and principal component analysis (PCA) 
      was fabricated for simultaneous and rapid determination of three polychlorinated 
      phenols (PCPs) including 2,4-dichlorophenol (2,4-DCP), 2,4,5-trichlorophenol 
      (2,4,5-TCP), and 2,3,4,6-tetrachlorophenol (2,3,4,6-TeCP). The aggregated Ag 
      nanoparticles (AgNPs) induced by inorganic salt ions were used as sensitive SERS 
      substrate, and the electromagnetic field distribution of AgNPs with different 
      distances was simulated by finite difference time domain (FDTD) to verify the 
      theory feasibility. The high throughput and rapid detection can be achieved by 
      commercial 96-pore plate. Under the optimum conditions, the linear relationship 
      between the Raman intensity and the concentrations of PCPs was established with 
      satisfied correlation coefficient. The limits of detection (LOD) for 2,4-DCP, 
      2,4,5-TCP, and 2,3,4,6-TeCP are 0.27 mg L(-1), 0.09 mg L(-1), and 0.10 mg L(-1) 
      by rules of 3sigma, respectively. The simultaneous quantitative analysis can be 
      achieved thanks to the independent Raman characteristic peaks of three PCPs. 
      Afterwards, the PCA method was used to eliminate the limitations of overlapping 
      of characteristic Raman peaks in structural analogues of 2,4-DCP, 2,4,5-TCP, and 
      2,3,4,6-TeCP. The recovery experiments including single PCPs and mixed PCP 
      samples show satisfied recoveries ranging from 85.0 to 113.9% and 80.4 to 114.0% 
      with RSDs in range of 0.4-9.5% and 1.1-10.7%, respectively. The proposed method 
      shows great potentials in rapid, high-throughput, and sensitive monitoring of the 
      contaminants in water and pesticide samples with similar structure. Here, we 
      introduced aggregated Ag nanoparticles (AgNPs) induced by inorganic salt ion for 
      simultaneous, rapid, and sensitive determination of polychlorinated phenols 
      (PCPs) including 2,4-dichlorophenol (2,4-DCP), 2,4,5-trichlorophenol (2,4,5-TCP), 
      and 2,3,4,6-tetrachlorophenol (2,3,4,6-TeCP) by surface-enhanced Raman 
      spectroscopy (SERS) combined with principal component analysis (PCA). The AgNPs 
      induced by inorganic salt ions were used as sensitive SERS substrate, and the 
      electromagnetic field distribution of AgNPs with different distances was 
      simulated by finite difference time domain (FDTD) to verify the theory 
      feasibility. The PCA method was used to eliminate the limitations of overlapping 
      of characteristic Raman peaks in structural analogues of 2,4-DCP, 2,4,5-TCP, and 
      2,3,4,6-TeCP. The proposed method shows great potentials in rapid, 
      high-throughput, and sensitive monitoring of the contaminants in water and 
      pesticide samples with similar structure.
CI  - (c) 2022. Springer-Verlag GmbH Germany, part of Springer Nature.
FAU - Ge, Kun
AU  - Ge K
AD  - School of Chemistry, Sun Yat-Sen University, Guangzhou, 510006, China.
FAU - Li, Yonghui
AU  - Li Y
AD  - Faculty of Food Science and Engineering, Kunming University of Science and 
      Technology, Kunming, 650500, China.
FAU - Wu, Qiyue
AU  - Wu Q
AD  - Faculty of Food Science and Engineering, Kunming University of Science and 
      Technology, Kunming, 650500, China.
FAU - Gu, Ying
AU  - Gu Y
AD  - Faculty of Food Science and Engineering, Kunming University of Science and 
      Technology, Kunming, 650500, China. guying@kust.edu.cn.
LA  - eng
GR  - 32102073/National Natural Science Foundation of China/
GR  - 2021J0058/Scientific Research Fund Project of Yunnan Provincial Department of 
      Education/
GR  - 202102AE090021/Sub-project of Yunnan Science and Technology Planning Project/
PT  - Journal Article
DEP - 20220110
PL  - Germany
TA  - Anal Bioanal Chem
JT  - Analytical and bioanalytical chemistry
JID - 101134327
SB  - IM
EIN - Anal Bioanal Chem. 2024 Feb;416(4):1101. PMID: 38093116
OTO - NOTNLM
OT  - Detection
OT  - Polychlorinated phenols
OT  - Principal component analysis
OT  - Screening
OT  - Surface-enhanced Raman spectroscopy
EDAT- 2022/01/11 06:00
MHDA- 2022/01/11 06:01
CRDT- 2022/01/10 12:27
PHST- 2021/10/28 00:00 [received]
PHST- 2022/01/04 00:00 [accepted]
PHST- 2021/12/23 00:00 [revised]
PHST- 2022/01/11 06:00 [pubmed]
PHST- 2022/01/11 06:01 [medline]
PHST- 2022/01/10 12:27 [entrez]
AID - 10.1007/s00216-022-03876-0 [pii]
AID - 10.1007/s00216-022-03876-0 [doi]
PST - ppublish
SO  - Anal Bioanal Chem. 2022 Mar;414(7):2385-2395. doi: 10.1007/s00216-022-03876-0. 
      Epub 2022 Jan 10.