PMID- 35010818 OWN - NLM STAT- MEDLINE DCOM- 20220124 LR - 20220124 IS - 1660-4601 (Electronic) IS - 1661-7827 (Print) IS - 1660-4601 (Linking) VI - 19 IP - 1 DP - 2022 Jan 4 TI - Association of Rare Earth Elements with Passive Smoking among Housewives in Shanxi Province, China. LID - 10.3390/ijerph19010559 [doi] LID - 559 AB - BACKGROUND: Rare earth elements (REEs) are emerging contaminants. Previous studies reported the association between REEs and active smoking, but little is known about the effects of passive smoking on this condition. In China, female passive smoking is widespread, particularly in rural areas. OBJECTIVE: This study aimed to estimate the relationship between REEs accumulation and passive smoking among rural housewives. METHODS: We recruited 385 subjects in Shanxi Province of northern China, of whom 117 housewives were exposed to passive smoking, and 268 were not. We analyzed 15 REEs in the hair of housewives with ICP-MS, including lanthanum, cerium, praseodymium, neodymium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, and yttrium. RESULTS: The results indicated higher levels of 14 REEs except for Sm in both the univariate and adjusted models among the housewives exposed to passive smoking. The increasing linear trend of adjusted odds ratios of 15 REEs supported their association. The Bayesian kernel machine regression (BKMR) models showed that 15 REEs had a significant overall effect, and Eu had a single-exposure effect with passive smoking. CONCLUSION: We concluded that passive smoking might be associated with increased exposure to REEs among rural housewives. FAU - Na, Jigen AU - Na J AD - Key Laboratory of Reproductive Health, National Health Commission of the People's Republic of China, Institute of Reproductive and Child Health, Peking University, Beijing 100191, China. AD - Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China. FAU - Chen, Huiting AU - Chen H AUID- ORCID: 0000-0001-6606-0549 AD - Key Laboratory of Reproductive Health, National Health Commission of the People's Republic of China, Institute of Reproductive and Child Health, Peking University, Beijing 100191, China. AD - Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China. FAU - An, Hang AU - An H AD - Key Laboratory of Reproductive Health, National Health Commission of the People's Republic of China, Institute of Reproductive and Child Health, Peking University, Beijing 100191, China. AD - Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China. FAU - Li, Nan AU - Li N AUID- ORCID: 0000-0002-2932-9649 AD - Key Laboratory of Reproductive Health, National Health Commission of the People's Republic of China, Institute of Reproductive and Child Health, Peking University, Beijing 100191, China. AD - Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China. FAU - Yan, Lailai AU - Yan L AD - Department of Laboratorial Science and Technology, School of Public Health, Peking University, Beijing 100191, China. FAU - Ye, Rongwei AU - Ye R AD - Key Laboratory of Reproductive Health, National Health Commission of the People's Republic of China, Institute of Reproductive and Child Health, Peking University, Beijing 100191, China. AD - Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China. FAU - Li, Zhiwen AU - Li Z AD - Key Laboratory of Reproductive Health, National Health Commission of the People's Republic of China, Institute of Reproductive and Child Health, Peking University, Beijing 100191, China. AD - Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China. LA - eng PT - Journal Article DEP - 20220104 PL - Switzerland TA - Int J Environ Res Public Health JT - International journal of environmental research and public health JID - 101238455 RN - 0 (Metals, Rare Earth) RN - 0 (Tobacco Smoke Pollution) RN - 06SSF7P179 (Terbium) RN - 77B218D3YE (Erbium) RN - NKN7EZA750 (Praseodymium) SB - IM MH - Bayes Theorem MH - China/epidemiology MH - Erbium MH - Female MH - Humans MH - *Metals, Rare Earth/analysis MH - Praseodymium MH - Terbium MH - *Tobacco Smoke Pollution PMC - PMC8744937 OTO - NOTNLM OT - biomarker OT - emerging contaminant OT - housewives OT - passive smoking OT - rare earth elements COIS- All authors declare they have no potential competing interests. EDAT- 2022/01/12 06:00 MHDA- 2022/01/27 06:00 PMCR- 2022/01/04 CRDT- 2022/01/11 01:12 PHST- 2021/11/30 00:00 [received] PHST- 2021/12/28 00:00 [revised] PHST- 2021/12/30 00:00 [accepted] PHST- 2022/01/11 01:12 [entrez] PHST- 2022/01/12 06:00 [pubmed] PHST- 2022/01/27 06:00 [medline] PHST- 2022/01/04 00:00 [pmc-release] AID - ijerph19010559 [pii] AID - ijerph-19-00559 [pii] AID - 10.3390/ijerph19010559 [doi] PST - epublish SO - Int J Environ Res Public Health. 2022 Jan 4;19(1):559. doi: 10.3390/ijerph19010559.