PMID- 35012516
OWN - NLM
STAT- MEDLINE
DCOM- 20220411
LR  - 20220411
IS  - 1471-2458 (Electronic)
IS  - 1471-2458 (Linking)
VI  - 22
IP  - 1
DP  - 2022 Jan 10
TI  - Obesity indicators as mediators of association between daytime napping and type 2 
      diabetes mellitus: the Guangzhou Biobank Cohort Study.
PG  - 56
LID - 10.1186/s12889-021-12451-8 [doi]
LID - 56
AB  - OBJECTIVE: To examine the mediating effect of obesity indicators on the 
      association between daytime napping and type 2 diabetes mellitus (T2DM) 
      qualitatively and quantitatively using baseline data from the Guangzhou Biobank 
      Cohort Study. METHODS: Twenty-nine thousand three hundred fifty-five participants 
      aged 50+ years were included in this cross-sectional study. Mediation analysis 
      was used to assess the mediating effect of body mass index (BMI), waist 
      circumference (WC), hip circumference (HC), waist-to-hip ratio (WHR) and 
      waist-to-height ratio (WHtR) on the association between daytime napping and T2DM 
      after adjustment for sex, age, education, occupation, smoking status, alcohol use 
      and physical activity. RESULTS: The mean (standard deviation) age of participants 
      was 61.5 ( 7.1) years. The prevalence of T2DM and daytime napping was 12.5% and 
      65.2%, respectively. After adjustment for potential confounders, WC, WHR and WHtR 
      showed partial mediating effects on the association between daytime napping and 
      T2DM, with the proportion (95% confidence interval) of mediation effect being 
      10.17% (8.14-14.43%), 14.91% (11.95-21.24%) and 9.36% (7.49-13.29%), 
      respectively. No mediating effect of BMI or HC on the association between daytime 
      napping and T2DM was found. CONCLUSIONS: Our results showed significant mediating 
      effects of WC, WHR and WHtR on the association between daytime napping and T2DM, 
      suggesting that waist circumference management could be important in daytime 
      nappers.
CI  - (c) 2022. The Author(s).
FAU - Xiao, Jing Yi
AU  - Xiao JY
AD  - School of Public Health, Sun Yat-sen University, No. 74 Zhongshan 2nd Road, 
      Guangzhou, Guangdong Province, China.
FAU - Zhang, Wei Sen
AU  - Zhang WS
AD  - Guangzhou Twelfth People's Hospital, Guangzhou, 510620, China.
FAU - Jiang, Chao Qiang
AU  - Jiang CQ
AD  - Guangzhou Twelfth People's Hospital, Guangzhou, 510620, China.
FAU - Jin, Ya Li
AU  - Jin YL
AD  - Guangzhou Twelfth People's Hospital, Guangzhou, 510620, China.
FAU - Zhu, Feng
AU  - Zhu F
AD  - Guangzhou Twelfth People's Hospital, Guangzhou, 510620, China.
FAU - Cheng, Kar Keung
AU  - Cheng KK
AD  - Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
FAU - Lam, Tai Hing
AU  - Lam TH
AD  - School of Public Health, the University of Hong Kong, Hong Kong, Hong Kong.
FAU - Xu, Lin
AU  - Xu L
AD  - School of Public Health, Sun Yat-sen University, No. 74 Zhongshan 2nd Road, 
      Guangzhou, Guangdong Province, China. xulin27@mail.sysu.edu.cn.
AD  - School of Public Health, the University of Hong Kong, Hong Kong, Hong Kong. 
      xulin27@mail.sysu.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20220110
PL  - England
TA  - BMC Public Health
JT  - BMC public health
JID - 100968562
SB  - IM
MH  - Biological Specimen Banks
MH  - Body Mass Index
MH  - Cohort Studies
MH  - Cross-Sectional Studies
MH  - *Diabetes Mellitus, Type 2/epidemiology
MH  - Humans
MH  - Obesity/epidemiology
MH  - Risk Factors
MH  - Waist Circumference
MH  - Waist-Hip Ratio
PMC - PMC8744231
OTO - NOTNLM
OT  - Daytime napping
OT  - Mediation analysis
OT  - Obesity
OT  - Type 2 diabetes mellitus
COIS- All authors declare no competing interests.
EDAT- 2022/01/12 06:00
MHDA- 2022/04/12 06:00
PMCR- 2022/01/10
CRDT- 2022/01/11 05:50
PHST- 2021/10/25 00:00 [received]
PHST- 2021/12/21 00:00 [accepted]
PHST- 2022/01/11 05:50 [entrez]
PHST- 2022/01/12 06:00 [pubmed]
PHST- 2022/04/12 06:00 [medline]
PHST- 2022/01/10 00:00 [pmc-release]
AID - 10.1186/s12889-021-12451-8 [pii]
AID - 12451 [pii]
AID - 10.1186/s12889-021-12451-8 [doi]
PST - epublish
SO  - BMC Public Health. 2022 Jan 10;22(1):56. doi: 10.1186/s12889-021-12451-8.