PMID- 35016525
OWN - NLM
STAT- MEDLINE
DCOM- 20220713
LR  - 20220713
IS  - 2224-5839 (Electronic)
IS  - 2224-5820 (Linking)
VI  - 11
IP  - 6
DP  - 2022 Jun
TI  - Long-term follow-up in quality of life before and after endoscopic thoracic 
      sympathicotomy in 367 patients with palmar hyperhidrosis.
PG  - 1961-1968
LID - 10.21037/apm-21-2860 [doi]
AB  - BACKGROUND: Palmar hyperhidrosis (PH) hinders daily activities and deteriorates 
      quality of life (QOL). Endoscopic thoracic sympathicotomy (ETS) is safe and 
      efficient as the gold standard treatment for PH. So far, the long-term change of 
      QOL after surgery has not been fully characterized, which is important to 
      evaluate clinical benefits and helped to identify the true beneficiaries. In the 
      current study, we aimed to investigate the long-term outcome of ETS by comparing 
      their preoperative QOL with a follow-up QOL. METHODS: This study enrolled 367 
      patients with PH who underwent ETS between March 2018 and March 2019. All 
      patients were surveyed by a web-based questionnaire adapted from de Campos 
      Quality-of-life Questionnaire for Evaluation of Hyperhidrosis, and compared to 
      their preoperative results. RESULTS: After a median follow-up of 14 months 
      [interquartile range (IQR), 9-21 months], improvement in QOL was reported in 
      90.7% of patients. Compared to preoperative QOL [median (Md) =40, IQR, 37-45], 
      postoperative QOL was significantly improved (Md =20, IQR, 13-23; P<0.001). A 
      higher QOL score was noticed in patients with severer PH at diagnosis, whereas no 
      significant difference was observed among postoperative QOL regarding the 
      severity of PH. Subclinical compensatory hyperhidrosis (CH) occurred in 94.6% of 
      post-ETS cases after long-term follow-up. The score of postoperative QOL was 
      significantly positively correlated to the severity of CH (rs=0.14; P=0.009). 
      CONCLUSIONS: Improvement in QOL sustained for a long-term period after receiving 
      ETS for PH. Almost all patients developed subclinical CH on other body sites in 
      the long run, with an impairment in QOL correlating with the severity of CH. 
      Further investigations on the developing patterns of CH and clinical coping 
      strategy are warranted to improve the long-term outcome of ETS.
FAU - Zhang, Dongkun
AU  - Zhang D
AD  - Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou, China.
FAU - Zhuang, Weitao
AU  - Zhuang W
AD  - Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou, China; Shantou University Medical 
      College, Shantou, China.
FAU - Lan, Zihua
AU  - Lan Z
AD  - Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou, China; Shantou University Medical 
      College, Shantou, China.
FAU - Huang, Shujie
AU  - Huang S
AD  - Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou, China; Shantou University Medical 
      College, Shantou, China.
FAU - Gao, Zhen
AU  - Gao Z
AD  - Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou, China; The Second School of Clinical 
      Medicine, Southern Medical University, Guangzhou, China.
FAU - Chen, Qibin
AU  - Chen Q
AD  - Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou, China; Guangdong Cardiovascular 
      Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical 
      Sciences, Guangzhou, China.
FAU - Ben, Xiaosong
AU  - Ben X
AD  - Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou, China.
FAU - Tang, Jiming
AU  - Tang J
AD  - Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou, China.
FAU - Zhou, Haiyu
AU  - Zhou H
AD  - Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou, China.
FAU - Xie, Liang
AU  - Xie L
AD  - Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou, China.
FAU - Qiao, Guibin
AU  - Qiao G
AD  - Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou, China.
LA  - eng
PT  - Journal Article
DEP - 20220110
PL  - China
TA  - Ann Palliat Med
JT  - Annals of palliative medicine
JID - 101585484
SB  - IM
MH  - Follow-Up Studies
MH  - Humans
MH  - *Hyperhidrosis/diagnosis/surgery
MH  - Patient Satisfaction
MH  - *Quality of Life
MH  - Sympathectomy/methods
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Palmar hyperhidrosis
OT  - compensatory hyperhidrosis (CH)
OT  - endoscopic thoracic sympathicotomy
OT  - quality of life
EDAT- 2022/01/13 06:00
MHDA- 2022/07/14 06:00
CRDT- 2022/01/12 05:34
PHST- 2021/10/05 00:00 [received]
PHST- 2021/12/24 00:00 [accepted]
PHST- 2022/01/13 06:00 [pubmed]
PHST- 2022/07/14 06:00 [medline]
PHST- 2022/01/12 05:34 [entrez]
AID - apm-21-2860 [pii]
AID - 10.21037/apm-21-2860 [doi]
PST - ppublish
SO  - Ann Palliat Med. 2022 Jun;11(6):1961-1968. doi: 10.21037/apm-21-2860. Epub 2022 
      Jan 10.