PMID- 35019569
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220210
IS  - 2576-6422 (Electronic)
IS  - 2576-6422 (Linking)
VI  - 3
IP  - 12
DP  - 2020 Dec 21
TI  - Aggregation-Induced Electrochemiluminescence Immunosensor Based on 
      9,10-Diphenylanthracene Cubic Nanoparticles for Ultrasensitive Detection of 
      Aflatoxin B(1).
PG  - 8933-8942
LID - 10.1021/acsabm.0c01201 [doi]
AB  - 9,10-Diphenylanthracene cubic nanoparticles (DPA CNPs) with aggregation-induced 
      emission characteristic (AIEgens) were synthesized through a facile 
      reprecipitation method; then, a bright and stable electrochemiluminescence (ECL) 
      signal can be observed when the DPA CNPs were modified at the glassy carbon 
      electrode (GCE) in the presence of Tri-n-propylamine (TPA). This phenomenon is 
      ascribed to the molecules with restricted movement that greatly blocked the 
      energy leakage during the relaxation of the excited state, which facilitated the 
      emission of energy in the form of photons. In addition, the size confinement 
      effect of DPA CNPs in the aggregated state effectively enhanced the ECL emission. 
      The application of DPA CNPs with AIE characteristics in an 
      electrochemiluminescence immunosensor has not been reported. In this 
      contribution, a free-label aggregation-induced electrochemiluminescence 
      immunosensor based on DPA CNPs was fabricated and a simple strategy for 
      ultrasensitive detection of aflatoxin B(1) (AFB(1)) was proposed. The ECL signal 
      is quenched linearly in the range of 0.01 pg/mL to 100 ng/mL for AFB(1), and the 
      detection limit is 3 fg/mL. In summary, the prepared sensor exhibits high 
      sensitivity, acceptable accuracy, good anti-interference ability and stability, 
      and satisfactory detection toward AFB(1) in walnut samples. Therefore, the 
      fabricated immunosensor will have significant applications in the fields of food, 
      medicine, and so on.
FAU - Lv, Xiaoyi
AU  - Lv X
AD  - State Key Laboratory of Biobased Material and Green Papermaking, School of Food 
      Science and Engineering, Qilu University of Technology, Shandong Academy of 
      Sciences, Jinan 250353, China.
FAU - Xu, Xiaoyun
AU  - Xu X
AD  - State Key Laboratory of Biobased Material and Green Papermaking, School of Food 
      Science and Engineering, Qilu University of Technology, Shandong Academy of 
      Sciences, Jinan 250353, China.
FAU - Miao, Tian
AU  - Miao T
AD  - State Key Laboratory of Biobased Material and Green Papermaking, School of Food 
      Science and Engineering, Qilu University of Technology, Shandong Academy of 
      Sciences, Jinan 250353, China.
FAU - Zang, Xufeng
AU  - Zang X
AUID- ORCID: 0000-0002-3503-584X
AD  - College of Science, Huzhou University, Huzhou, Zhejiang 313000, China.
FAU - Geng, Chao
AU  - Geng C
AD  - State Key Laboratory of Biobased Material and Green Papermaking, School of Food 
      Science and Engineering, Qilu University of Technology, Shandong Academy of 
      Sciences, Jinan 250353, China.
FAU - Li, Yanping
AU  - Li Y
AD  - State Key Laboratory of Biobased Material and Green Papermaking, School of Food 
      Science and Engineering, Qilu University of Technology, Shandong Academy of 
      Sciences, Jinan 250353, China.
FAU - Cui, Bo
AU  - Cui B
AD  - State Key Laboratory of Biobased Material and Green Papermaking, School of Food 
      Science and Engineering, Qilu University of Technology, Shandong Academy of 
      Sciences, Jinan 250353, China.
FAU - Fang, Yishan
AU  - Fang Y
AUID- ORCID: 0000-0001-9575-8997
AD  - State Key Laboratory of Biobased Material and Green Papermaking, School of Food 
      Science and Engineering, Qilu University of Technology, Shandong Academy of 
      Sciences, Jinan 250353, China.
LA  - eng
PT  - Journal Article
DEP - 20201203
PL  - United States
TA  - ACS Appl Bio Mater
JT  - ACS applied bio materials
JID - 101729147
SB  - IM
OTO - NOTNLM
OT  - 9,10-diphenylanthracene cubic nanoparticles
OT  - aflatoxin B1
OT  - aggregation-induced
OT  - electrochemiluminescence immunosensor
OT  - ultrasensitive detection
EDAT- 2020/12/21 00:00
MHDA- 2020/12/21 00:01
CRDT- 2022/01/12 12:18
PHST- 2022/01/12 12:18 [entrez]
PHST- 2020/12/21 00:00 [pubmed]
PHST- 2020/12/21 00:01 [medline]
AID - 10.1021/acsabm.0c01201 [doi]
PST - ppublish
SO  - ACS Appl Bio Mater. 2020 Dec 21;3(12):8933-8942. doi: 10.1021/acsabm.0c01201. 
      Epub 2020 Dec 3.