PMID- 35020024 OWN - NLM STAT- MEDLINE DCOM- 20220405 LR - 20220531 IS - 1432-5195 (Electronic) IS - 0341-2695 (Print) IS - 0341-2695 (Linking) VI - 46 IP - 4 DP - 2022 Apr TI - Polyethylene wear of dual mobility cups: a comparative analysis based on patient-specific finite element modeling. PG - 779-787 LID - 10.1007/s00264-022-05305-4 [doi] AB - PURPOSE: Concerns remain about potential increased wear with dual mobility cups related to the multiple articulations involved in this specific design of implant. This finite element analysis study aimed to compare polyethylene (PE) wear between dual mobility cup and conventional acetabular component, and between the use of conventional ultra-high molecular weight PE (UHMWPE) and highly cross-linked PE (XPLE). METHODS: Patient-specific finite element modeling was developed for 15 patients undergoing primary total hip arthroplasty (THA). Five acetabular components were 3D modeled and compared in THA constructs replicating existing implants: a dual mobility cup with a 22.2-mm-diameter femoral head against UHMWPE or XLPE (DM22PE or DM22XL), a conventional cup with a 22.2-mm-diameter femoral head against UHMWPE (SD22PE) and a conventional cup with a 32-mm-diameter femoral head against UHMWPE or XLPE (SD32PE or SD32XL). RESULTS: DM22PE produced 4.6 times and 5.1 times more volumetric wear than SD32XL and DM22XL (p < 0.0001, Cohen's d = 6.97 and 7.11; respectively). However, even if significant, the differences in volumetric wear between DM22XL and SD32XL as well as between DM22PE and SD22PE or SD32PE were small according to their effect size (p < 0.0001, Cohen's |d|= 0.48 to 0.65) and could be therefore considered as clinically negligible. CONCLUSION: When using XLPE instead of UHMWPE, dual mobility cup with a 22.2-mm-diameter femoral head produced a similar amount of volumetric wear than conventional acetabular component with a 32-mm-diameter femoral head against XLPE. Therefore, XLPE is advocated in dual mobility cup to improve its wear performance. CI - (c) 2022. The Author(s). FAU - Wegrzyn, Julien AU - Wegrzyn J AUID- ORCID: 0000-0003-0194-8664 AD - Department of Orthopedic Surgery, Lausanne University Hospital-Centre Hospitalier Universitaire Vaudois-CHUV, Hopital Orthopedique, Avenue Pierre-Decker, 4, CH-1011, Lausanne, Switzerland. julien.wegrzyn@chuv.ch. FAU - Antoniadis, Alexander AU - Antoniadis A AD - Department of Orthopedic Surgery, Lausanne University Hospital-Centre Hospitalier Universitaire Vaudois-CHUV, Hopital Orthopedique, Avenue Pierre-Decker, 4, CH-1011, Lausanne, Switzerland. FAU - Sarshari, Ehsan AU - Sarshari E AD - Laboratory of Biomechanical Orthopedics, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland. FAU - Boubat, Matthieu AU - Boubat M AD - Laboratory of Biomechanical Orthopedics, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland. FAU - Terrier, Alexandre AU - Terrier A AD - Department of Orthopedic Surgery, Lausanne University Hospital-Centre Hospitalier Universitaire Vaudois-CHUV, Hopital Orthopedique, Avenue Pierre-Decker, 4, CH-1011, Lausanne, Switzerland. AD - Laboratory of Biomechanical Orthopedics, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20220112 PL - Germany TA - Int Orthop JT - International orthopaedics JID - 7705431 RN - 9002-88-4 (Polyethylene) SB - IM MH - *Arthroplasty, Replacement, Hip/adverse effects MH - Finite Element Analysis MH - *Hip Prosthesis MH - Humans MH - Polyethylene MH - Prosthesis Design MH - Prosthesis Failure PMC - PMC8930956 OTO - NOTNLM OT - Dual mobility cup OT - Highly cross-linked polyethylene OT - Patient-specific modeling OT - Polyethylene mobile component OT - Polyethylene wear COIS- JW receives royalties from Dedienne sante and serves as paid consultant for Stryker Orthopaedics and Lima corporate. AA serves as paid consultant for Stryker Orthopaedics. ES, MB and AT have no conflict of interest to disclose. EDAT- 2022/01/13 06:00 MHDA- 2022/04/06 06:00 PMCR- 2022/01/12 CRDT- 2022/01/12 12:32 PHST- 2021/10/05 00:00 [received] PHST- 2022/01/04 00:00 [accepted] PHST- 2022/01/13 06:00 [pubmed] PHST- 2022/04/06 06:00 [medline] PHST- 2022/01/12 12:32 [entrez] PHST- 2022/01/12 00:00 [pmc-release] AID - 10.1007/s00264-022-05305-4 [pii] AID - 5305 [pii] AID - 10.1007/s00264-022-05305-4 [doi] PST - ppublish SO - Int Orthop. 2022 Apr;46(4):779-787. doi: 10.1007/s00264-022-05305-4. Epub 2022 Jan 12.