PMID- 35022123
OWN - NLM
STAT- MEDLINE
DCOM- 20220114
LR  - 20220531
IS  - 1751-7125 (Electronic)
IS  - 1540-9740 (Linking)
VI  - 19
IP  - 6
DP  - 2021
TI  - Dupilumab for the Treatment of Actinic Prurigo.
PG  - 471-472
AB  - A 42-year-old Latino man with a medical history of vitiligo presented to our 
      outpatient clinic with a 25-year history of a recurrent, itchy eruption on his 
      face and hands. Physical examination revealed pink, scaly, erythematous, 
      lichenified papules and plaques with overlying crusts, photodistributed on the 
      nose, chin, cheeks, hands, and ears (Figures 1a and 2a). The lips were edematous 
      with hemorrhagic crusting, and conjunctival injection and partial corneal 
      opacities were noted (Figures 1b-1c). Histologic evaluation demonstrated 
      psoriasiform hyperplasia with hyper-granulosis and a superficial perivascular 
      infiltrate composed of lymphocytes, histiocytes, and eosinophils. Human leukocyte 
      antigen (HLA) class II typing was positive for HLA-DRB1*0407, thus confirming the 
      diagnosis of actinic prurigo (AP).
FAU - Perz, Allison M
AU  - Perz AM
AD  - Cooper Medical School of Rowan University, Camden, NJ; perza2@rowan.edu.
FAU - Fawaz, Bilal
AU  - Fawaz B
AD  - Division of Dermatology, Cooper University Hospital, Camden, NJ.
FAU - Pyle, Tia
AU  - Pyle T
AD  - Division of Dermatology, Cooper University Hospital, Camden, NJ.
FAU - Butala, Niraj
AU  - Butala N
AD  - Department of Dermatology, Southern California Permanente Medical Group, 
      Lancaster, CA.
FAU - Green, Justin J
AU  - Green JJ
AD  - Division of Dermatology, Cooper University Hospital, Camden, NJ.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20211201
PL  - United States
TA  - Skinmed
JT  - Skinmed
JID - 101168327
RN  - 0 (Antibodies, Monoclonal, Humanized)
RN  - 420K487FSG (dupilumab)
RN  - Actinic Prurigo
SB  - IM
MH  - Adult
MH  - Antibodies, Monoclonal, Humanized/*therapeutic use
MH  - Humans
MH  - Male
MH  - *Photosensitivity Disorders/drug therapy
MH  - *Skin Diseases, Genetic/drug therapy
EDAT- 2022/01/14 06:00
MHDA- 2022/01/15 06:00
CRDT- 2022/01/13 05:44
PHST- 2022/01/13 05:44 [entrez]
PHST- 2022/01/14 06:00 [pubmed]
PHST- 2022/01/15 06:00 [medline]
PST - epublish
SO  - Skinmed. 2021 Dec 1;19(6):471-472. eCollection 2021.