PMID- 35028843
OWN - NLM
STAT- MEDLINE
DCOM- 20220131
LR  - 20220131
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 29
IP  - 8
DP  - 2022 Feb
TI  - Antibiotics, antibiotic-resistant bacteria, and resistance genes in aquaculture: 
      risks, current concern, and future thinking.
PG  - 11054-11075
LID - 10.1007/s11356-021-17825-4 [doi]
AB  - Aquaculture is remarkably one of the most promising industries among the 
      food-producing industries in the world. Aquaculture production as well as fish 
      consumption per capita have been dramatically increasing over the past two 
      decades. Shifting of culture method from semi-intensive to intensive technique 
      and applying of antibiotics to control the disease outbreak are the major factors 
      for the increasing trend of aquaculture production. Antibiotics are usually 
      present at subtherapeutic levels in the aquaculture environment, which increases 
      the selective pressure to the resistant bacteria and stimulates resistant gene 
      transfer in the aquatic environment. It is now widely documented that antibiotic 
      resistance genes and resistant bacteria are transported from the aquatic 
      environment to the terrestrial environment and may pose adverse effects on human 
      and animal health. However, data related to antibiotic usage and bacterial 
      resistance in aquaculture is very limited or even absent in major 
      aquaculture-producing countries. In particular, residual levels of antibiotics in 
      fish and shellfish are not well documented. Recently, some of the countries have 
      already decided the maximum residue levels (MRLs) of antibiotics in fish muscle 
      or skin; however, many antibiotics are yet not to be decided. Therefore, an 
      urgent universal effort needs to be taken to monitor antibiotic concentration and 
      resistant bacteria particularly multiple antibiotic-resistant bacteria and to 
      assess the associated risks in aquaculture. Finally, we suggest to take an 
      initiative to make a uniform antibiotic registration process, to establish the 
      MRLs for fish/shrimp and to ensure the use of only aquaculture antibiotics in 
      fish and shellfish farming globally.
CI  - (c) 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, 
      part of Springer Nature.
FAU - Hossain, Anwar
AU  - Hossain A
AD  - Department of Fisheries, Faculty of Biological Sciences, University of Dhaka, 
      Dhaka, 1000, Bangladesh. ahossain@du.ac.bd.
FAU - Habibullah-Al-Mamun, Md
AU  - Habibullah-Al-Mamun M
AD  - Department of Fisheries, Faculty of Biological Sciences, University of Dhaka, 
      Dhaka, 1000, Bangladesh.
FAU - Nagano, Ichiro
AU  - Nagano I
AD  - Central Research Laboratory, Tokyo Innovation Center, Nippon Suisan Kaisha Ltd, 
      32-3 Nanakuni 1-Chome, Hacjioji, Tokyo, 192-0991, Japan.
FAU - Masunaga, Shigeki
AU  - Masunaga S
AD  - Faculty of Environment and Information Sciences, Yokohama National University, 
      Yokohama, 240-8501, Japan.
FAU - Kitazawa, Daisuke
AU  - Kitazawa D
AD  - Center for Integrated Underwater Observation Technology, Institute of Industrial 
      Science, The University of Tokyo, Chiba, 277-8574, Japan.
FAU - Matsuda, Hiroyuki
AU  - Matsuda H
AD  - Faculty of Environment and Information Sciences, Yokohama National University, 
      Yokohama, 240-8501, Japan.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20220114
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Animals
MH  - *Anti-Bacterial Agents/pharmacology
MH  - *Aquaculture
MH  - Bacteria
MH  - Drug Resistance, Bacterial/genetics
MH  - Drug Resistance, Microbial/genetics
MH  - Fishes
MH  - Humans
OTO - NOTNLM
OT  - Antibiotics
OT  - Aquaculture
OT  - Ecological risk
OT  - Human health risk
OT  - Regulations
OT  - Resistance risk
EDAT- 2022/01/15 06:00
MHDA- 2022/02/01 06:00
CRDT- 2022/01/14 06:15
PHST- 2021/07/02 00:00 [received]
PHST- 2021/11/24 00:00 [accepted]
PHST- 2022/01/15 06:00 [pubmed]
PHST- 2022/02/01 06:00 [medline]
PHST- 2022/01/14 06:15 [entrez]
AID - 10.1007/s11356-021-17825-4 [pii]
AID - 10.1007/s11356-021-17825-4 [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2022 Feb;29(8):11054-11075. doi: 
      10.1007/s11356-021-17825-4. Epub 2022 Jan 14.