PMID- 35036238 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220119 IS - 2168-8184 (Print) IS - 2168-8184 (Electronic) IS - 2168-8184 (Linking) VI - 14 IP - 1 DP - 2022 Jan TI - Adalimumab-Induced Erythema Multiforme in a Patient With Rheumatoid Arthritis: A Case Report. PG - e21126 LID - 10.7759/cureus.21126 [doi] LID - e21126 AB - Tumor necrosis factor-alpha (TNF-alpha) inhibitors are a group of biological medications that revolutionized the treatment of rheumatoid arthritis (RA) and several other inflammatory autoimmune diseases. The wide use of these drugs has been associated with some adverse reactions. Erythema multiforme (EM) is an immune-mediated cutaneous disorder that represents a hypersensitivity reaction to infections, vaccines, and some medications. We present a female patient with EM with characteristic skin lesions following anti-TNF-alpha medication adalimumab for rheumatoid arthritis. CI - Copyright (c) 2022, Mohammed et al. FAU - Mohammed, Jinan Q AU - Mohammed JQ AD - Dermatology, Basrah Teaching Hospital, Basrah, IRQ. FAU - Mahmmod, Zainab AU - Mahmmod Z AD - Department of Medicine, College of Medicine/ University of Basrah, Basrah, IRQ. FAU - Mathkhor, Abdulsatar J AU - Mathkhor AJ AD - Rheumatology, Basrah Teaching Hospital, Basrah, IRQ. LA - eng PT - Case Reports DEP - 20220111 PL - United States TA - Cureus JT - Cureus JID - 101596737 PMC - PMC8752112 OTO - NOTNLM OT - adalimumab OT - anti-tumor necrosis factor-alpha OT - case report OT - erythema multiforme OT - rheumatoid arthritis COIS- The authors have declared that no competing interests exist. EDAT- 2022/01/18 06:00 MHDA- 2022/01/18 06:01 PMCR- 2022/01/11 CRDT- 2022/01/17 06:02 PHST- 2022/01/11 00:00 [accepted] PHST- 2022/01/17 06:02 [entrez] PHST- 2022/01/18 06:00 [pubmed] PHST- 2022/01/18 06:01 [medline] PHST- 2022/01/11 00:00 [pmc-release] AID - 10.7759/cureus.21126 [doi] PST - epublish SO - Cureus. 2022 Jan 11;14(1):e21126. doi: 10.7759/cureus.21126. eCollection 2022 Jan.