PMID- 35038790
OWN - NLM
STAT- MEDLINE
DCOM- 20220325
LR  - 20220325
IS  - 2055-5822 (Electronic)
IS  - 2055-5822 (Linking)
VI  - 9
IP  - 2
DP  - 2022 Apr
TI  - Assessment of congestion and clinical outcomes in patients with chronic heart 
      failure using shear wave elasticity.
PG  - 1279-1286
LID - 10.1002/ehf2.13809 [doi]
AB  - AIMS: The relief of congestion is essential for the prevention of worsening heart 
      failure (HF) resulting in hospitalizations. Assessment of the degree of organ 
      congestion in the chronic phase of HF is important for determining therapeutic 
      strategies. The aim of this study was to evaluate the efficacy of shear wave (SW) 
      elasticity for assessing congestion and clinical outcomes in patients with 
      chronic HF. METHODS AND RESULTS: We prospectively enrolled 345 consecutive 
      patients with chronic HF who underwent SW elastography at outpatient clinic. 
      Patients were divided into two groups according to the median value of SW 
      elasticity: low group (SW elasticity <6.4 kPa, n = 176) and high group (SW 
      elasticity >/=6.4 kPa, n = 169). The endpoint was cardiovascular death or 
      hospitalization for HF. During the median follow-up period of 19 months (range: 
      7-36 months), cardiovascular death or hospitalization for HF occurred in 4 
      patients of low group and 27 patients of high group. In high group, 8 patients 
      died, and 19 patients were hospitalized for HF. In low group, 3 patients died, 
      and 1 patient was hospitalized. Kaplan-Meier analysis showed that the event-free 
      survival rate was worse in high group than in low group (log-rank test, 
      P = 0.004). After adjusting for variables, high SW elasticity was independently 
      related to cardiac events. In multivariate regression analysis, SW elasticity was 
      correlated with left atrial volume index, early diastolic mitral inflow velocity 
      to mitral annular velocity ratio, and inferior vena cava diameter. CONCLUSIONS: 
      The SW elasticity reflected haemodynamic congestion in patients with chronic HF, 
      which was related to cardiac events.
CI  - (c) 2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on 
      behalf of European Society of Cardiology.
FAU - Nakayama, Rie
AU  - Nakayama R
AUID- ORCID: 0000-0002-7489-5703
AD  - Department of Cardiovascular Medicine, Okayama University Graduate School of 
      Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, 
      Okayama, 700-8558, Japan.
FAU - Takaya, Yoichi
AU  - Takaya Y
AD  - Department of Cardiovascular Medicine, Okayama University Graduate School of 
      Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, 
      Okayama, 700-8558, Japan.
FAU - Nakamura, Kazufumi
AU  - Nakamura K
AD  - Department of Cardiovascular Medicine, Okayama University Graduate School of 
      Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, 
      Okayama, 700-8558, Japan.
FAU - Takemoto, Rika
AU  - Takemoto R
AD  - Division of Medical Support, Okayama University Hospital, Okayama, Japan.
FAU - Toh, Norihisa
AU  - Toh N
AD  - Department of Cardiovascular Medicine, Okayama University Graduate School of 
      Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, 
      Okayama, 700-8558, Japan.
FAU - Ito, Hiroshi
AU  - Ito H
AD  - Department of Cardiovascular Medicine, Okayama University Graduate School of 
      Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, 
      Okayama, 700-8558, Japan.
LA  - eng
PT  - Journal Article
DEP - 20220117
PL  - England
TA  - ESC Heart Fail
JT  - ESC heart failure
JID - 101669191
SB  - IM
MH  - Elasticity
MH  - *Elasticity Imaging Techniques/methods
MH  - *Heart Failure/complications/diagnosis
MH  - Hospitalization
MH  - Humans
MH  - Prognosis
PMC - PMC8934942
OTO - NOTNLM
OT  - Congestion
OT  - Heart failure
OT  - Prognosis
OT  - Shear wave elasticity
COIS- The authors declare that they have no conflict of interest.
EDAT- 2022/01/18 06:00
MHDA- 2022/03/26 06:00
PMCR- 2022/01/17
CRDT- 2022/01/17 20:24
PHST- 2021/12/06 00:00 [revised]
PHST- 2021/09/14 00:00 [received]
PHST- 2022/01/05 00:00 [accepted]
PHST- 2022/01/18 06:00 [pubmed]
PHST- 2022/03/26 06:00 [medline]
PHST- 2022/01/17 20:24 [entrez]
PHST- 2022/01/17 00:00 [pmc-release]
AID - EHF213809 [pii]
AID - 10.1002/ehf2.13809 [doi]
PST - ppublish
SO  - ESC Heart Fail. 2022 Apr;9(2):1279-1286. doi: 10.1002/ehf2.13809. Epub 2022 Jan 
      17.