PMID- 35040695
OWN - NLM
STAT- MEDLINE
DCOM- 20220908
LR  - 20221014
IS  - 1552-6887 (Electronic)
IS  - 0898-2643 (Print)
IS  - 0898-2643 (Linking)
VI  - 34
IP  - 4-5
DP  - 2022 Aug-Sep
TI  - Trajectories of General Health Status and Depressive Symptoms Among Persons With 
      Cognitive Impairment in the United States.
PG  - 720-735
LID - 10.1177/08982643211060948 [doi]
AB  - ObjectivesTo identify and examine heterogeneous trajectories of general health 
      status (GHS) and depressive symptoms (DS) among persons with cognitive impairment 
      (PCIs). Methods: We use group-based trajectory models to study 2361 PCIs for GHS 
      and 1927 PCIs for DS from the National Health and Aging Trends Survey 2011-2018, 
      and apply multinomial logistic regressions to predict identified latent 
      trajectory group memberships using individual characteristics. Results: For both 
      GHS and DS, there were six groups of PCIs with distinct trajectories over a 
      7-year period. More than 40% PCIs experienced sharp declines in GHS, and 35.5% 
      experienced persistently poor GHS. There was greater heterogeneity in DS 
      trajectories with 55% PCIs experiencing improvement, 16.4% experiencing 
      persistently high DS, and 30.5% experiencing deterioration. Discussion: The GHS 
      trajectories illustrate the heavy burden of poor and declining health among PCIs. 
      Further research is needed to understand the factors underlying stable or 
      improving DS despite declining GHS.
FAU - Zang, Emma
AU  - Zang E
AD  - Department of Sociology, 5755Yale University, New Haven, CT, USA.
FAU - Guo, Anna
AU  - Guo A
AD  - Department of Biostatistics, 5755Yale University, New Haven, CT, USA.
FAU - Pao, Christina
AU  - Pao C
AD  - Department of Sociology, 6396University of Oxford, Oxford, UK.
FAU - Lu, Nancy
AU  - Lu N
AUID- ORCID: 0000-0002-5646-0546
AD  - Harvard Medical School, 1811Harvard University, Boston, MA, USA.
FAU - Wu, Bei
AU  - Wu B
AUID- ORCID: 0000-0002-6891-244X
AD  - Rory Meyers College of Nursing, 5894New York University, New York, NY, USA.
FAU - Fried, Terri R
AU  - Fried TR
AUID- ORCID: 0000-0001-8083-8265
AD  - Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.
AD  - Department of Medicine, Yale School of Medicine, New Haven, CT, USA.
LA  - eng
GR  - P30 AG021342/AG/NIA NIH HHS/United States
GR  - R21 AG074238/AG/NIA NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20220118
PL  - United States
TA  - J Aging Health
JT  - Journal of aging and health
JID - 8912686
MH  - Aging/psychology
MH  - *Cognitive Dysfunction/epidemiology
MH  - *Depression/epidemiology/psychology
MH  - Health Status
MH  - Humans
MH  - Logistic Models
MH  - Longitudinal Studies
MH  - United States/epidemiology
PMC - PMC9289075
MID - NIHMS1795011
OTO - NOTNLM
OT  - Alzheimer's disease
OT  - cognitive aging
OT  - depression
OT  - health disparities
EDAT- 2022/01/19 06:00
MHDA- 2022/09/09 06:00
PMCR- 2022/09/08
CRDT- 2022/01/18 12:20
PHST- 2022/01/19 06:00 [pubmed]
PHST- 2022/09/09 06:00 [medline]
PHST- 2022/01/18 12:20 [entrez]
PHST- 2022/09/08 00:00 [pmc-release]
AID - 10.1177/08982643211060948 [doi]
PST - ppublish
SO  - J Aging Health. 2022 Aug-Sep;34(4-5):720-735. doi: 10.1177/08982643211060948. 
      Epub 2022 Jan 18.